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Metabotropic Antagonists

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Image	Description	Biochem/physiol Actions	CAS Number	Product #
	(±)-α-Methyl-(4-carboxyphenyl)glycine	Competitive antagonist at Group 1 (mGluR₁ and mGluR₅) and Group 2 (mGluR₂ and mGluR₃) metabotropic glutamate receptors.	146669-29-6	M4796
	(±)-α-Methyl-(4-sulfonophenyl)glycine	Antagonist at Group III metabotropic glutamate receptors.	169209-64-7	M5046
	(+)-α-Methyl-4-carboxyphenylglycine solid	Competitive metabotropic glutamate receptor antagonist.	150145-89-4	M196
	(S)-2-Amino-2-methyl-4-phosphonobutyric acid hydrochloride synthetic, solid	Selective mGluR_4,6,7 metabotropic glutamate receptor antagonist.		M5560
	6-Methyl-2-(phenylethynyl)pyridine solid	Highly selective, non-competitive mGluR₅ metabotropic glutamate receptor antagonist.	219911-35-0	M5435
	DL-2-Amino-3-phosphonopropionic acid	Potent metabotropic glutamate receptor antagonist.	20263-06-3	A4910
	L-(+)-2-Amino-3-phosphonopropionic acid	Potent antagonist at metabotropic glutamic acid receptors.	23052-80-4	A154
	AIDA solid	Selective mGluR₁metabotropic glutamate receptor antagonist.	168560-79-0	A254
	CPCCOEt >98% (HPLC), solid	Potent, selective non-competitive mGluR₁ metabotropic glutamate receptor antagonist.	179067-99-3	C9611
	NPS 2390 ≥99% (HPLC), solid	Type I metabotropic glutamate receptor antagonist	226878-01-9	N4786
	SIB 1757 ≥99% (HPLC), crystalline	Highly selective mGlu₅ metabotropic glutamate receptor antagonist.		S9186
	SIB 1893 >99%, solid	Selective and noncompetitive mGlu₅ metabotropic glutamate receptor antagonist.	7370-21-0	S9311

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