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Enzyme Inhibitors
> Acetylcholinesterase
Acetylcholinesterase
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Description
Biochem/physiol Actions
Product #
9-Amino-1,2,3,4-
tetrahydroacridine hydrochloride hydrate ≥99%
A3773
1,5-Bis(4-
allyldimethylammoniumphenyl)pentan-3-one dibromide
Selective acetylcholinesterase inhibitor.
A9013
Deoxypeganine hydrochloride dihydrate ≥99% (HPLC), solid
Inhibits cholinesterases reversibly.
D7314
Diisopropylfluorophosphate
Potent inhibitor of serine proteases such as trypsin and chymotrypsin, and of acetylcholinesterase; also inhibits cathepsin G, cholinesterase, coagulation factor Xa, leucocyte elastase, pancreatic elastase, tissue kallikrein, plasmin, subtilisin, and thrombin. Inhibition of acetylcholinesterase makes this compound especially toxic. Inhibits apoptosis induced by ricin and bacterial toxins.
D0879
Edrophonium chloride
Acetycholinesterase inhibitor
E3256
Eserine
Acetylcholinesterase inhibitor that crosses the blood-brain barrier and forms a carbamylated enzyme complex with acetyl cholinesterase that degrades slowly.
E8375
Eserine purum, ≥98.0% (N)
Acetylcholinesterase inhibitor that crosses the blood-brain barrier and forms a carbamylated enzyme complex with acetyl cholinesterase that degrades slowly.
45710
Eserine hemisulfate salt
Acetylcholinesterase inhibitor that crosses the blood-brain barrier and forms a carbamylated enzyme complex with acetyl cholinesterase that degrades slowly.
E8625
Fasciculin 2 from
Dendroaspis angusticeps
(eastern green mamba)
Acetylcholinesterase inhibitor. Fasciculin 2 acts by binding to the gorge entrance of acetylcholinesterase, sterically blocking ligand access and causing other conformational changes in the enzyme. Also inhibits butylcholinesterase.
F4293
Galanthamine hydrobromide from
Lycoris
sp. ≥94% (TLC)
Cholinesterase inhibitor; reverses scopolamine-induced amnesia; antimyasthenic.
G1660
(−)-Huperzine A
Acetylcholinesterase inhibitor; active enantiomer.
H5902
(±)-Huperzine A from synthetic, ≥98% (TLC)
Acetylcholinesterase inhibitor.
H5777
Neostigmine bromide ≥98% (TLC and titration), powder
Reversible inhibitor of acetylcholinesterase that is similar to eserine, but does not cross the blood-brain barrier.
N2001
Neostigmine methyl sulfate
Reversible inhibitor of acetylcholinesterase that is similar to eserine, but does not cross the blood-brain barrier.
N2126
Peganole 95%, solid
Acetylcholinestearase inhibitor; psychotomimetic agent in dogs and cats.
P3240
Pyridostigmine bromide
Acetylcholinesterase inhibitor.
P9797
W-84 dibromide ≥98% (HPLC), solid
Potent allosteric modulator of M
2
muscarinic acetylcholine receptors.
W0641
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