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Inositol Phosphates

Inositol phosphates are important intracellular second messengers in eukaryotic cells. Inositol, a cyclic molecule with six hydroxyl groups, forms the hydrophobic head group of membrane inositol phospholipids. The actions of lipid kinases and phosphatases on the inositol ring of inositol phospholipids generate a variety of phosphoinositol phospholipids. As a result of upstream signaling events, specific phospholipases are activated, cleave phosphoinositol phospholipids, and release intracellular inositol phosphate second messenger molecules.
The most studied inositol phosphate second messenger is inositol 1,4,5-trisphosphate (IP₃). IP₃ is released from phosphatidylinositol 4,5-bisphosphate (PIP₂) by the action of phospholipase C-β and is responsible for the release of calcium ions from intracellular stores in the endoplasmic reticulum.

Reset Table

Product #	Description
P4240	1,2-Dipalmitoylphosphatidylinositol 3,4,5-trisphosphate >98%
P6990	1,2-Dipalmitoylphosphatidylinositol 3,4-diphosphate ≥98%, solid
P7115	1,2-Dipalmitoylphosphatidylinositol 4,5-diphosphate ≥98%, solid
P1652	D-α-Phosphatidylcholine, dipalmitoyl ≥99%
I8636	D-myo-Inositol 1,3,4,5-tetrakis(phosphate) ammonium salt ~95%
I0143	D-myo-Inositol 1,3,4,5-tetrakis(phosphate) potassium salt
I9766	D-myo-Inositol 1,4,5-tris-phosphate hexasodium salt
I0510	D-myo-Inositol 1,4-bisphosphate potassium salt from bovine brain, ~98% (TLC)
I0146	D-myo-Inositol 2,4,5-tris-phosphate ammonium sodium salt
I3264	D-myo-Inositol 4,5-bisphosphate ammonium salt
P9953	L-α-Phosphatidyl-D-myo-inositol 3,4,5-triphosphate, dioctanoyl
P4725	L-α-Phosphatidyl-D-myo-inositol 3,4-diphosphate, dioctanoyl
P5713	L-α-Phosphatidyl-D-myo-inositol 3,5-diphosphate, dipalmitoyl
P5578	L-α-Phosphatidyl-D-myo-inositol 3-monophosphate, dioctanoyl
P3953	L-α-Phosphatidyl-D-myo-inositol 3-monophosphate, dipalmitoyl
P3584	L-α-Phosphatidyl-D-myo-inositol 4,5-diphosphate, dioctanoyl
P7686	L-α-Phosphatidyl-D-myo-inositol 4-monophosphate, dipalmitoyl
P1168	L-α-Phosphatidyl-D-myo-inositol 5-monophosphate, dipalmitoyl
P9763	L-α-Phosphatidylinositol 4,5-diphosphate sodium salt from bovine brain >98% (TLC)
P1368	L-α-Phosphatidylinositol dipalmitoyl ammonium salt >98% (TLC)
I7012	D-myo-Inositol 1,4,5-trisphosphate potassium salt synthetic
L9908	LY-294,002 hydrochloride solid, ≥98% (HPLC)
P8615	Phosphoinositide 3-kinase p110γ human >95% (SDS-PAGE), recombinant, expressed in insect cells, buffered aqueous glycerol solution
P6023	Phosphoinositides sodium salt from bovine brain
Q0125	Quercetin dihydrate ≥98% (HPLC), powder
W1628	Wortmannin from Penicillium funiculosum, ≥98% (HPLC and TLC), powder
I9261	myo-Inositol 1,3,4,5,6-pentakisphosphate ≥95%
I5125	myo-Inositol ≥99%
I7508	myo-Inositol cell culture tested, insect cell culture tested
I8132	scyllo-Inositol ≥98%

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