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Description
Biochem/physiol Actions
Product #
Atroxin
™
from
Bothrops atrox
venom
BioChemika
11335
α-Bungarotoxin from
Bungarus multicinctus
(Formosan Banded Krait) solid
Neurotoxin which binds irreversibly to motor endplate of acetylcholine receptors; prevents opening of nicotinic receptor-associated ion channels.
T3019
α-
Bungarotoxin−FITC labeled from
Bungarus multicinctus
(Formosan Banded Krait)
Fluorescent label for nicotinic receptors on the motor endplate.
T9641
α-Bungarotoxin-
tetramethylrhodamine from
Bungarus multicinctus
(Formosan Banded Krait)
Useful for detecting the distribution of nicotinic acetylcholine receptors at neuromuscular junctions.
T0195
β-Bungarotoxin from
Bungarus multicinctus
(Formosan Banded Krait)
Phospholipase A
2
neurotoxin
; destroys synaptic vesicles and inhibits acetylcholine release.
T5644
Cardiotoxin from
Naja mossambica mossambica
C9759
Cardiotoxin 1 from
Naja naja atra
(Formosan Cobra)
Cardiotoxin I is the component of the snake venom that is responsible for skeletal muscle necrosis. It also induces increases in capillary permeability that can be prevented by H
1
histamine receptor antagonists, such as dephenhydramine, promethazine and cyproheptadine. This indicates that cardiotoxin may induce histamine release.
C3987
α-Cobratoxin from
Naja naja kaouthia
Long chain post-synaptic neurotoxin that binds nicotinic receptors and blocks cholinergic neurotransmission at the neuromuscular junction; binding is irreversible.
C6903
Cobra venom anti-complementary protein from
Naja naja kaouthia
lyophilized powder
C8406
Crotaline
C2401
α-Dendrotoxin
Blocks slowly inactivating outward K
+
current; blocks voltage-gated K
+
-channels in rat brain synaptosomes; increases acetylcholine release at neuromuscular junction.
D9667
δ-Dendrotoxin ≥98% (SDS-PAGE), lyophilized powder
Antagonizes the binding of p-aminoclonidine to α
2
-adrenoreceptors; blocks outward K
+
current; blocks voltage-gated K
+
-channels in rat brain synaptosomes.
D0439
Echistatin α1 isoform, ≥95% (HPLC)
Disintegrins represent a novel family of integrin β1 and β3 inhibitor proteins isolated from viper venoms. They are low molecular-weight, cysteine-rich peptides containing the Arg-Gly-Asp (RGD) sequence. They are the most potent known inhibitors of integrin function. Disintegrins interfere with cell adhesion to the extracellular matrix, including adhesion of melanoma cells and fibroblasts to fibronectin, and are potent inhibitors of platelet aggregation.
E2138
Echistatin from
Echis carinatus
lyophilized powder, γ-irradiated
Disintegrins represent a novel family of integrin β1 and β3 inhibitor proteins isolated from viper venoms. They are low molecular-weight, cysteine-rich peptides containing the Arg-Gly-Asp (RGD) sequence. They are the most potent known inhibitors of integrin function. Disintegrins interfere with cell adhesion to the extracellular matrix, including adhesion of melanoma cells and fibroblasts to fibronectin, and are potent inhibitors of platelet aggregation.
E1518
Kistrin from
Agkistrodon rhodostoma
(Malayan pit viper) venom lyophilized powder, γ-irradiated
Disintegrins represent a novel family of integrin β1 and β3 inhibitor proteins isolated from viper venoms. They are low molecular-weight, cysteine-rich peptides containing the Arg-Gly-Asp (RGD) sequence. They are the most potent known inhibitors of integrin function. Disintegrins interfere with cell adhesion to the extracellular matrix, including adhesion of melanoma cells and fibroblasts to fibronectin, and are potent inhibitors of platelet aggregation.
K4755
Myotoxin II from
Crotalus viridis concolor
(midget faded rattlesnake)
Components of rattlesnake venom, causing instantaneous paralysis of bitten prey. Some sequence homology with crotamine; presumed to have similar modes of action.
M9172
Neurotoxin II from
Naja naja oxiana
lyophilized powder
Postsynaptic neurotoxin.
T3768
Sarafotoxin S6a1 ≥97% (HPLC)
S1522
Sarafotoxin S6c ≥97% (HPLC)
ET
B
agonist; toxin with strong vasoconstrictor activity
S6545
Snake venom from
Agkistrodon acutus
(Formosan hundred-pace snake) venom
V3625
Snake venom from
Agkistrodon bilineatus
(Tropical Moccasin)
V7876
Snake venom from
Agkistrodon contortrix contortrix
V3875
Snake venom from
Agkistrodon contortrix laticinctus
V4000
Snake venom from
Agkistrodon contortrix mokason
(Northern Copperhead)
V4125
Snake venom from
Agkistrodon piscivorus leukostoma
V4375
Snake venom from
Agkistrodon piscivorus piscivorus
V4500
Snake venom from
Bitis arietans
V4750
Snake venom from
Bitis caudalis
V8627
Snake venom from
Bitis gabonica
(Gaboon Viper)
V4875
Snake venom from
Bothrops alternata
V5250
Snake venom from
Bothrops jararaca
not lyophilized
Contains botrocetin (venom coagglutinin) which causes aggregation of blood platelets in the presence of the von Willebrand component of the factor VIII macromolecular complex over a wider range than ristocetin.
V5625
Snake venom from
Bungarus caeruleus
(Indian Krait)
V6250
Snake venom from
Bungarus fasciatus
(Banded Krait)
V6500
Snake venom from
Bungarus multicinctus
(Formosan Banded Krait)
Source of α- and β-bungarotoxin; has high anticholinesterase activity
V6625
Snake venom from
Causus rhombeatus
V6750
Snake venom from
Crotalus atrox
(Western Diamondback Rattlesnake)
V7000
Snake venom from
Crotalus basiliscus
V0877
Snake venom from
Crotalus viridis viridis
V7625
Snake venom from
Dendroaspis polylepis polylepis
(Black mamba)
V8000
Snake venom from
Dispholidus typus
V8125
Snake venom from
Echis carinatus
V8250
Snake venom from
Lachesis muta
V7376
Snake venom from
Laticauda semifasciata
(Sea Snake)
V6751
Snake venom from
Micrurus carinacauda demerilii
V3376
Snake venom from
Micrurus frontalis
V3503
Snake venom from
Micrurus fulvius
V8750
Snake venom from
Micrurus surinamensis
V8127
Snake venom from
Naja melanoleuca
(Black Cobra)
Has high acetylcholinesterase activity
V9000
Snake venom from
Naja naja
V4378
Snake venom from
Naja naja atra
(Formosan Cobra)
V9250
Snake venom from
Naja naja kaouthia
V9125
Snake venom from
Naja naja sputatrix
V2252
Snake venom from
Naja nivea
V9625
Snake venom from
Notechis scutatus scutatus
V0251
Snake venom from
Ophiophagus hannah
(
Naja hannah
, King Cobra)
V0376
Snake venom from
Oxyuranus scutellatus
V3129
Snake venom from
Pseudechis australis
V0751
Snake venom from
Pseudechis colletti guttatus
V0876
Snake venom from
Pseudechis porphyriacus
V1251
Snake venom from
Sepedon (Hemachatus) hemachatus
(Ringhals Cobra)
has acetylcholinesterase activity
V5750
Snake venom from
Trimeresurus elegans
(Sakishima habu snake)
V6377
Snake venom from
Trimeresurus flavoviridis
(Habu Snake)
V1751
Snake venom from
Trimeresurus okinavensis
V2001
Snake venom from
Trimeresurus popeorum
V7251
Snake venom from
Trimeresurus stejnegeri
V7002
Snake venom from
Vipera ammodytes
(Long-nosed viper)
V2251
Snake venom from
Vipera lebetina
V7378
Snake venom from
Vipera russelli
(Russell's Viper)
V2501
TaiCatoxin from
Oxyuranus s. scutellatus
(Taipan snake) venom >97%, lyophilized powder
Selective and reversible blocker of voltage-dependent L-type Ca
2+
channels in excitable membranes.
T183
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