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Synthetic Reagents

Alcohol oxidation is one of the most frequently performed oxidation reactions in organic chemistry. In collaboration with Professor Shannon Stahl, Aldrich offers the Stahl Aerobic Oxidation Solutions: 796549 and coming soon, 796557. Both solutions contain 1-methylimidazole (NMI), 2,2?-bipyridyl (bpy), and either TEMPO or ABNO; just add the copper catalyst and your substrate.

View Details for Aldrich Product No. 796549 Stahl Aerobic Oxidation TEMPO solution, 0.2 M in acetonitrile
Synthetic Reagents

PhenoFluor is an innovative deoxyfluorination reagent, which is unique in both its ability to directly fluorinate phenolic hydroxyls without preactivation and can also regioselectively fluorinate density functionalized late-stage intermediates and other lead candidates in drug discovery. One of the caveats toward this reagent is its high sensitivity to both air and moisture, making it nearly impossible to handle outside of a glovebox without significantly compromising the quality of the material. To solve this problem, Aldrich Chemistry now offers PhenoFluor as a solution in toluene (0.1 M) (795291), which can be readily used outside of a glovebox now that it is packaged in our innovative 25 mL Sure/Seal bottle.

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