New Products for Chemical Synthesis

Move Your Research Forward Faster with Aldrich Chemistry

Featured New Products

Chemical Biology

The Baseclick cell proliferation kits are an efficient replacement for the anti-BrdU assay. Baseclick kits use incorporation of the nucleoside EdU into replicating DNA of live cells in a method similar to BrdU incorporation. Instead of antibody recognition with anti-BrdU, the assay uses efficient Cu-induced click chemistry to attach a fluorescent probe to the EdU. The EdU protocol requires fewer steps and is faster, taking ∼1 ½ hr total time (30 min for the click ligation). Assays are available in formats for imaging, flow cytometry, high throughput screening, and in vivo studies. Kits are also available with different fluorescent probes with excitation at 488, 555, 594, and 647 to allow multiplexing with other fluorescent probes.

Click here to view the list of available cell proliferation kits.
Synthetic Reagents

PhenoFluor is an innovative deoxyfluorination reagent, which is unique in both its ability to directly fluorinate phenolic hydroxyls without preactivation and can also regioselectively fluorinate density functionalized late-stage intermediates and other lead candidates in drug discovery. One of the caveats toward this reagent is its high sensitivity to both air and moisture, making it nearly impossible to handle outside of a glovebox without significantly compromising the quality of the material. To solve this problem, Aldrich Chemistry now offers PhenoFluor as a solution in toluene (0.1 M) (795291), which can be readily used outside of a glovebox now that it is packaged in our innovative 25 mL Sure/Seal bottle.

Click on the area of interest below to Add Aldrich and view the complete list of the latest products to hit our shelf. Our list of new products is frequently updated, just one of the ways that Aldrich is moving your research forward faster.