Technology Spotlights

New! Buchwald Portfolio – Precatalysts and Ligands

By Application Area

Cross-Coupling

• Application Guide for Palladium Catalyzed Cross -Coupling Reactions (2011)
• DalPhos Ligands (2011)
• 2^nd Generation Buchwald Precatalysts (2011)
• TPGS–750–M: Second Generation Amphiphile for Organometallic Chemistry in Water @ RT (2011)
• Potassium Organotrifluoroborates (2011)
• New MIDA Boronates  (2011)
• Bis-Hydroxamic Acid (BHA) Ligands – New Chiral Ligands for Asymmetric Oxidation (2009) 
• BRIDP from Takasago - New Ligands for Cross-Coupling Catalysis (2008)
• MIDA Boronates (2008)
• Symphos Ligands for Efficient Suzuki Cross-Coupling (2008)
• cataCXium®—Ligands and Complexes for Efficient Cross-Coupling Reactions (2008)
• A-Phos Palladium Complexes for Efficient Suzuki Coupling (2008)
• Buchwald Ligands For C–C, C–N, And C–O Bond Formation (2007)
• New Cyclopropane Reagent: Potassium Cyclopropyltrifluoroborate (2007)
• Organosilanols: Powerful Nucleophiles for Pd-Catalyzed Cross-Coupling (2007)
• Organotrifluoroborates: Potent Boronic Acid Surrogates (2006)
• PEPPSI™ Catalysts (2006)
• Reaxa Technology: Easier, Faster, and Cleaner Reactions (2007)

Organocatalysis

• (S)-(–)-5-(2-Pyrrolidinyl)-1H-tetrazole – L-Proline’s Isosteric Companion in Organocatalysis (2009)
• Chiral Phase-Transfer Catalysts—Maruoka Catalysts (2008)
• Chiral Phosphoric Acids: New Organocatalysts for Reductive Amination (2008)
• Jacobsen Thioureas: New Versatile Organocatalysts (2007)
• Jørgensen’s Organocatalysts (2007)
• MacMillan Imidazolidine OrganoCatalysts™ (2006)

Asymmetric Synthesis

• EZ-CrotylMix Reagents  (2011)
• Leighton's Strained Silacycles: Powerful Enantioselective Allylation Reagents (2010)
• Solvias MeOBIPHEP Ligands (2008)
• ChiroSolv® Resolving Kits: Facile and Rapid Chiral Separation (2008)
• Trost Ligands for Asymmetric Allylic Alkylation (AAA) (2007)
• Umicore Precatalysts for Asymmetric Reactions (2007)
• (R)-(+)- and (S)-(–)-Stericol®: New, Effective Chiral Auxiliaries (2007)
• catASium®—Essential Elements for Asymmetric Hydrogenations (2008)
• Takasago Ligands and Complexes for Asymmetric Reactions (2008)
• Diazaphospholane Ligands for Catalytic Asymmetric Transformations (2007)
• Soderquist Reagents: For allyl-, allenyl-, propargylboration (2007)
• QuinoxP*: Air-Stable and Highly Efficient Chiral Ligands (2006)
• Shvo's Catalyst: Efficient Catalyst for Enzyme Mediated Dynamic Kinetic Resolution (DKR)  (2006)
• New Chiral Auxiliaries (2006)
• Carreira Dolefin Ligands (2006)
• DuPhos and BPE Ligands: Highly Efficient Privileged Ligands (2006)
• DSM MonoPhos™ Family (2006)
• Gleason Chiral Auxiliary (2006)
• Efficient and Selective Catalysts for Asymmetric Synthesis (2006)
• Ellman's Sulfinamides (2-methyl-2-propanesulfinamide) (2005)
• Chiral Quest Phosphine Ligands for Asymmetric Hydrogenation (2005)
• CBS Catalysts (2005)

Synthetic Reagents

• New Diazoacetate Formulations (2011)
• Potassium Carbobenzyloxycyanamide: An Efficient Reagent for Amine Guanylation (2011)
• New Arene Trifluoromethylation Reagent: (Phen)Cu-CF₃ (2011)
• Stable Fluorinating Reagents (2010)
• New Reagents for Selective Metalation, Deprotonation, and Additions (2009)
• COMU – Safer and More Efficient Peptide Coupling Reagent (2009)
• Super Silyl Protecting Groups – Unique Reactivity in C–C Bond Forming Reactions (2009)
• DIH - Highly Efficient and Economical Reagent for Iodination (2009)
• Dudley Reagents: Benzyl and p-Methoxy Benzyl Protections Using Benzyloxypyridinium Triflate and 2-(4-Methoxybenzyloxy)-4-methylquinoline (2008)
• IPNBSH: A Reagent for the Simple Reduction of Alcohols (2007)
• DABAL-Me3: An Air Stable "Methyl Anion" (2007)
• Phosgene Generation Kit (2007)
• New Benzotriazole Reagents (2006)
• Benzoylation Reagents: Simple tools for α-oxygenation of aldehydes (2006)
• Diazald®: The Preferred Method For Diazomethane Generation (2006)
• Stabilized 2-Iodoxybenzoic Acid (SIBX) (2005)
• Iodotoluene Difluoride - A New, Mild Oxidation and Fluorination Reagents (2005)
• Lithium Aminoborohydride (LAB) Reagents (2005)
• Extremely Strong, Non-ionic Phosphazene Bases (2005)
• N-Acylbenzotriazoles from Aldrich: Neutral Acylating Reagents (2005)
• New, Safer, NIMBA-Stabilized BH3 THF Solutions (2005)

Green Chemistry

• Alkali Metal Silica Gels from SiGNa (2009)
• PTS: Amphiphile for Organic Synthesis in Water (2008)

C-H Reactions

• White Catalyst: A Catalyst for Allylic C–H Oxidation and Amination (2007)
• Rh2(esp)2: An Exceptionally Efficient and Selective Catalyst for C-H Amination (2005)

High-Throughput Synthesis

• ChemDose®: Convenient Dosing of Catalysts and Reagents (2007)
• Microreactor Explorer (MRE) Kit (2007)

Catalysis

• Metathesis: Ruthenium-Based Metathesis Catalysts (2007)
• Gold Catalysts — 21st Century 'Gold Rush' (2007)
• New Hydroazidation Catalyst for Facile Preparation of Organoazides (2006)
• Hydrosilyation Catalysts (2006)
• Catalysis Screening Kits (2006)
• N-Heterocyclic Carbene (NHC) Ligands (2005)

Chemical Ligation

• The Staudinger Ligation: A High-Yield, Chemoselective, and Mild Synthetic Method (2007)
• Click Chemistry: A "Click" Away from Drug Discovery (2006)

Ionic Liquids

• CBILS®: A Revolutionary Tool for ionic liquid synthesis (2007)
• Ionic Liquids for Catalysis (2005)
• Basionic™ Ionic Liquids (2005)