Rieke Organozinc Solutions

Organozinc reagents react with a variety of electrophiles and have been employed in numerous organic transformations such as cross-coupling reactions,¹ conjugate additions,² and electrophilic amination reactions.³ Much of their utility stems from their compatibility with a broad spectrum of functional groups. Interestingly, the choice of a preparative route to organozinc products does play an important role in their subsequent reactivity and stability. Sigma-Aldrich offers a comprehensive line of Rieke^® Organozincs that are stable as solutions in tetrahydrofuran. The list below contains our latest additions to this line of useful reagents. If you do not see the reagent you need, “please bother us” at mredlich@sial.com.

Click here to view our organozincs Chemfile. Vol. 2 No. 5

Product Name	Product #
4-(Ethoxycarbonyl)phenylzinc bromide, 0.5M solution in tetrahydrofuran	520284
5-Ethoxycarbonyl-2-thienylzinc bromide,0.5M solution in tetrahydrofuran	533548
4-Iodobenzylzinc bromide, 0.5M solution in tetrahydrofuran	533289
3-Iodobenzylzinc bromide, 0.5M solution in tetrahydrofuran	533297
2-Iodobenzylzinc bromide 0.5M in tetrahydrofuran	635650
2-Acetoxyphenyl zinc iodide, 0.5M solution in tetrahydrofuran	630357
4-Acetoxyphenyl zinc iodide, 0.5M solution in tetrahydrofuran	630365
3-Acetoxyphenyl zinc iodide, 0.5M solution in tetrahydrofuran	630373
5-Acetoxypentyl zinc bromide, 0.5M solution in tetrahydrofuran	630381
4-Acetoxybutyl zinc bromide, 0.5M solution in tetrahydrofuran	630403
2-Biphenylzinc iodide, 0.5M solution in tetrahydrofuran	630411
5-Ethoxycarbonyl-2-furylzinc bromide, 0.5M solution in tetrahydrofuran	641812

References:
(1) (a)Akritopoulou-Zanze, l. et al. Bioorg. Med. Chem. Lett. 2004, 14, 2079. (b) Fillon, H. et al. Tetrahedron 2003, 59, 8199.
(2)  Gomes, P. et al. Synlett 2002, 1673.
(3)  Velarde-Ortiz, R. et al. Tetrahedron Lett. 1998, 39, 9157