Chemical Biology

New Products from Aldrich Chemistry

Featured Chemical Biology Products

The Baseclick cell proliferation kits are an efficient replacement for the anti-BrdU assay. Baseclick kits use incorporation of the nucleoside EdU into replicating DNA of live cells in a method similar to BrdU incorporation. Instead of antibody recognition with anti-BrdU, the assay uses efficient Cu-induced click chemistry to attach a fluorescent probe to the EdU. The EdU protocol requires fewer steps and is faster, taking ∼1 ½ hr total time (30 min for the click ligation). Assays are available in formats for imaging, flow cytometry, high throughput screening, and in vivo studies. Kits are also available with different fluorescent probes with excitation at 488, 555, 594, and 647 to allow multiplexing with other fluorescent probes.

Click here to view the list of available cell proliferation kits.

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900603 (4-(2-(2-Aminoethoxy)ethoxy)phenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone ≥95% New C20H21NO4
900683 2-(3-(But-3-yn-1-yl)-3H-diazirin-3-yl)ethan-1-amine 95% New C7H11N3
900615 (4-Hydroxyphenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone ≥95% New C16H12O3
900555 (N-Isocyanoimino)triphenylphosphorane 95% New C19H16N2P
900619 4-(4-(Prop-2-yn-1-yloxy)benzoyl)benzaldehyde ≥95% New C17H12O3