Fast Deprotection 2′O-TBDMS RNA Phosphoramidites

Key features of Standard RNA Amidites
  • Industry standard 2′-TBDMS protective group
  • Lot-to-lot consistent purity and performance
  • Compatible with deprotection methods based on methylamine or AMA
  • Standard RNA Amidites provide excellent coupling results when used together with ETT or BTT as activator; best results are obtained with Activator 42®
  • Capping with standard acetic anhydride cappingreagent rather than with Fast Deprotection Cap A
  • Manufactured under a certified ISO 9001 quality system
  • Proligo Reagents offers RNA phosphoramidite monomers with Fast Deprotection Chemistry (tert-butylphenoxyacetyl (TAC) group).
  • Advantages of synthesis with TAC-protected RNA phosphoramidites
  • Increased synthesis yield and reduced purification efforts
  • Dramatically reduced deprotection times
  • Minimized exposure to alkaline deprotection medium
  • Minimized chain degradation during deprotection

DMT-2′O-TBDMS-rA(tac) Phosphoramidite

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A21208-HH DMT-2′O-TBDMS-rA(tac) Phosphoramidite C58H76N7O9PSi configured for PerkinElmer 8900
configured for Polygen
pkg of 1 × 0.5 g (A212081-01)
A212030 DMT-2′O-TBDMS-rA(tac) Phosphoramidite C58H76N7O9PSi configured for ABI
 
A212080 DMT-2′O-TBDMS-rA(tac) Phosphoramidite C58H76N7O9PSi configured for PerkinElmer
configured for Polygen
 
A212000 DMT-2′O-TBDMS-rA(tac) Phosphoramidite C58H76N7O9PSi    
A212050 DMT-2′O-TBDMS-rA(tac) Phosphoramidite C58H76N7O9PSi configured for MerMade
 

DMT-2′O-TBDMS-rC(tac) Phosphoramidite

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C21208-HH DMT-2′O-TBDMS-rC(tac) Phosphoramidite C57H76N5O10PSi configured for PerkinElmer 8900
configured for Polygen
pkg of 1 × 0.5 g (C212081-01)
C212030 DMT-2′O-TBDMS-rC(tac) Phosphoramidite C57H76N5O10PSi configured for ABI
 
C212080 DMT-2′O-TBDMS-rC(tac) Phosphoramidite C57H76N5O10PSi configured for PerkinElmer
configured for Polygen
 
C212050 DMT-2′O-TBDMS-rC(tac) Phosphoramidite C57H76N5O10PSi configured for (ÄKTA® and OligoPilot®)
 

DMT-2′O-TBDMS-rG(tac) Phosphoramidite

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G21208-HH DMT-2′O-TBDMS-rG(tac) Phosphoramidite C58H76N7O10PSi configured for PerkinElmer 8900
configured for Polygen
pkg of 1 × 0.5 g (G212081-01)
G2120MM-HH DMT-2′O-TBDMS-rG(tac) Phosphoramidite C58H76N7O10PSi configured for MerMade
pkg of 6 × 10 g (G212028-06)
G212000 DMT-2′O-TBDMS-rG(tac) Phosphoramidite C58H76N7O10PSi    
G212030 DMT-2′O-TBDMS-rG(tac) Phosphoramidite C58H76N7O10PSi configured for ABI
 
G212080 DMT-2′O-TBDMS-rG(tac) Phosphoramidite C58H76N7O10PSi configured for PerkinElmer
configured for Polygen
 
G212050 DMT-2′O-TBDMS-rG(tac) Phosphoramidite C58H76N7O10PSi configured for ABI
 

DMT-2′O-TBDMS-rU Phosphoramidite

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U21108-HH DMT-2′O-TBDMS-rU Phosphoramidite C45H61N4O9PSi configured for PerkinElmer 8900
configured for Polygen
pkg of 1 × 0.5 g (U211081-01)
U2110MM-HH DMT-2′O-TBDMS-rU Phosphoramidite C45H61N4O9PSi configured for MerMade
pkg of 1 × 0.5 g (U211041-01)
pkg of 1 × 1 g (U211043-01)
pkg of 6 × 10 g (U211028-06)
U211000 DMT-2′O-TBDMS-rU Phosphoramidite C45H61N4O9PSi    
U211030 DMT-2′O-TBDMS-rU Phosphoramidite C45H61N4O9PSi configured for ABI
 
U211080 DMT-2′O-TBDMS-rU Phosphoramidite C45H61N4O9PSi configured for PerkinElmer
configured for Polygen
 
U211040 DMT-2′O-TBDMS-rU Phosphoramidite C45H61N4O9PSi configured for MerMade
 
U211050 DMT-2′O-TBDMS-rU Phosphoramidite C45H61N4O9PSi configured for ÄKTA® and OligoPilot®