Copper

Sigma-Aldrich offers high quality copper catalysts for milder reactions with excellent yields for when chemical reactions are slow and require high temperatures. Among transition-metal mediated reactions to form carbon-carbon bonds and carbon-heteroatom bonds, copper catalysis is utilized in Ullmann reactions, Diels-Alder reactions, ring expansions, Castro-Stevens coupling, the Kharasch-Sosnovsky reaction, and a notable variant of the Huisgen 1,3-dipolar cycloaddition utilizing a Cu(I) catalyst developed independently by Meldal and Sharpless. This so-called Copper(I)-catalyzed Azide-Alkyne Cycloaddition (CuAAC) gives rise to a triazole from a terminal alkyne and an azide.

The catalysis of carbon-carbon bond and carbon-heteroatom bonds is central to synthetic chemistry and the synthesis of pharmacological, material, and biological compounds. Organic solvents and ligands as additives for copper-catalyzed cross-coupling reactions can improve reaction yields and utilize milder conditions. Sigma-Aldrich provides efficient copper catalysts and precatalysts as well as copper-containing Metal Organic Framework (MOF) components.

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00634 Ammonium tetrachlorocuprate(II) dihydrate puriss., ≥99.0% (AT) H8Cl4CuN2 · 2H2O
12801 Ammonium tetrachlorocuprate(II) dihydrate purum, ≥98% H8Cl4CuN2 · 2H2O
688614 Basolite® C 300 produced by BASF Green Alternative C18H6Cu3O12
696250 Bis(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)copper(I) tetrafluoroborate C54H72BCuF4N4
442305 Bis(ethylenediamine)copper(II) hydroxide solution 1.0 M in H2O C4H18CuN4O2
724491 (R,R)-(−)-N,N′-Bis(3-hydroxylsalicylidene)-1,2-cyclohexanediaminocopper(II)samarium isopropoxide C23H25CuN2O5Sm
762504 Bis[(tetrabutylammonium iodide)copper(I) iodide] 95% C32H72Cu2I4N2
437093 [Bis(trimethylsilyl)acetylene](hexafluoroacetylacetonato)copper(I) C13H19CuF6O2Si2
572144 Bromotris(triphenylphosphine)copper(I) 98% C54H45BrP3Cu
689815   BTS-Catalyst for gas purification  
766402 5-Chlorobenzo[b]phosphindole C12H8ClP
696307 Chloro[1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper(I) C27H36ClCuN2
715425 Chloro[1,3-Bis(2,4,6-trimethylphenyl)imidazol-2-ylidene]copper(I) 95% C21H24ClCuN2
763357 Chloro(1,5-cyclooctadiene)copper(I) dimer 95% C16H24Cl2Cu2
31284 Copper electrolytic, Analytical Reagent, Reag. Ph. Eur., ≥99.9% (complexometric), wire Cu
12816 Copper foil, ≥99.8% (complexometric) Cu
266086 Copper powder, <425 μm, 99.5% trace metals basis Cu
223409 Copper shot, −3-+14 mesh, 99% Cu
349216 Copper wire, diam. 1.0 mm, ≥99.9% Cu
326410 Copper wire, diam. 0.64 mm, 99.995% trace metals basis Cu
61139 Copper turnings, purum p.a., ≥99.0% Cu
61141 Copper purum p.a., ≥99.0%, powder Cu
311405 Copper ACS reagent, granular, 10-40 mesh, ≥99.90% Cu
709107 Copper in charcoal 3 wt. %  
403342 Copper(I) acetate 97% C2H3CuO2
25038 Copper(II) acetate monohydrate ≥99% (iodometric) C4H6CuO4 · H2O
217557 Copper(II) acetate monohydrate ACS reagent, ≥98% Green Alternative C4H6CuO4 · H2O
733245 Copper(II) acetate 1,2-bis(diphenylphosphino)ethane C30H30CuO4P2
C87851 Copper(II) acetylacetonate 97% C10H14CuO4
254185 Copper(I) bromide 99.999% trace metals basis BrCu
212865 Copper(I) bromide 98% BrCu
61163 Copper(I) bromide purum p.a., ≥98.0% (RT) BrCu
61165 Copper(II) bromide purum, ≥99.0% (RT) Br2Cu
221775 Copper(II) bromide 99% Br2Cu
230502 Copper(I) bromide dimethyl sulfide complex 99% C2H6BrCuS
731722 Copper(II) tert-butylacetoacetate 97% C16H26CuO6
12830 Copper(II) carbonate basic puriss., 54-57% Cu basis, green CH2Cu2O5
651745 Copper(I) chloride anhydrous, beads, ≥99.99% trace metals basis ClCu
229628 Copper(I) chloride ≥99.995% trace metals basis ClCu
256528 Copper(I) chloride ACS reagent, ≥90% ClCu
224332 Copper(I) chloride ReagentPlus®, purified, ≥99% ClCu
212946 Copper(I) chloride reagent grade, 97% ClCu
61168 Copper(I) chloride puriss. p.a., ACS reagent, ≥97.0% (RT) ClCu
61169 Copper(I) chloride purum, ≥97.0% (RT) ClCu
203149 Copper(II) chloride 99.999% trace metals basis Cl2Cu
222011 Copper(II) chloride 97% Cl2Cu
467847 Copper(II) chloride dihydrate ≥99.99% trace metals basis Cl2Cu · 2H2O
307483 Copper(II) chloride dihydrate ACS reagent, ≥99.0% Cl2Cu · 2H2O
701742 Copper(I) chloride - bis(lithium chloride) complex 1 M in THF Cl3CuLi2
697257 Copper(I) cyanide di(lithium chloride) complex solution in anhydrous tetrahydrofuran CCl2CuLi2N
341649 Copper(II) 3,5-diisopropylsalicylate hydrate C26H34CuO6 · xH2O
SYX00007 Copper (I) diphenylphosphinate AldrichCPR C12H10CuO2P
731714 copper(II) ethylacetoacetate 97% C12H18CuO6
337323 Copper(II) 2-ethylhexanoate C16H30CuO4
CDS013540 copper formate AldrichCPR C2H2CuO4
706515 Copper hydride (CuH) solution in toluene HCu
03140 Copper(I) iodide purum, ≥99.5% CuI
205540 Copper(I) iodide 98% CuI
715182 Copper iodide dimethyl sulfide complex 97% C6H18Cu4I4S3
61196 Copper(I) iodide trimethylphosphite complex ≥99.0% (RT) C3H9CuIO3P
715174 Copper(I) 3-methylsalicylate C8H7CuO3
223395 Copper(II) nitrate hemi(pentahydrate) ACS reagent, 98% CuN2O6 · 2.5H2O
678945 Copper(I) oxide nanospheres, dispersion, <350 nm particle size, 1.5 % (w/v) in ethanol Cu2O
12841 Copper(I) oxide ≥86% Cu basis, red Cu2O
241741 Copper(II) oxide ACS reagent, ≥99.0% CuO
310433 Copper(II) oxide needles, mixture of CuO and Cu2O, ACS reagent CuO
417971 Copper(II) oxide on alumina 14-20 mesh, extent of labeling: 13 wt. % loading CuO
CDS007432 copper oxychloride AldrichCPR H6Cl2Cu4O6
469130 Copper(II) sulfate pentahydrate 99.995% trace metals basis CuO4S · 5H2O
209198 Copper(II) sulfate pentahydrate ACS reagent, ≥98.0% CuO4S · 5H2O
C2284 Copper(II) sulfate solution 4 % (w/v) (prepared from copper (II) sulfate pentahydrate)  
61243 Copper(II) tartrate hydrate ≥95.0% (calc. on dry substance, RT) C4H4CuO6 · xH2O
CDS003249 copper(II) tetrafluoroborate, approx 45% in water AldrichCPR B2CuF8
682500 Copper(I) thiophene-2-carboxylate C5H3CuO2S
89025 Copper(I) thiophenolate ≥98.0% (RT) C6H5CuS
593192 Cu-TMEDA catalyst C12H34Cl2Cu2N4O2
283673 Copper(II) trifluoromethanesulfonate 98% C2CuF6O6S2
407240 Copper(I) trifluoromethanesulfonate benzene complex technical grade, 90% C2Cu2F6S2O6 · C6H6
513512 Copper(I) trifluoromethanesulfonate toluene complex 99.9% trace metals basis Green Alternative C9H8Cu2F6O6S2
747688 Copper(II) trifluoromethanesulfonimide hydrate C4CuF12N2O8S4 · xH2O
747629 Cu(dap)2 chloride C52H40ClCuN4O4
CDS003337 cupric carbonate AldrichCPR CCuO3
709581 {Cuprous 2-[(2-diphenylphosphino)benzylideneamino]-3,3-dimethylbutyrate,triflatesodium triflate} complex, dimer 98% C54H50Cu4F12N2Na2O16P2S4
703141 DABCO®-CuCl complex 97% C6H12ClCuN2
362204 Dichloro(1,10-phenanthroline)copper(II) 98% C12H8Cl2CuN2
224308 Dilithium tetrachlorocuprate(II) solution 0.1 M in THF Cl4CuLi2
762458 (R)-(DTBM-SEGPHOS®)CuH solution 0.001 M in toluene C74H101CuO8P2
512494 (Ethylcyclopentadienyl)(triphenylphosphine)copper(I) C25H24CuP
706000 Fluorotris(triphenylphosphine)copper(I) 95% (by HMR) C54H45CuFP3
735116 Iodo(triethyl phosphite)copper(I) 97% C6H16CuIO3P
736627 Mesitylcopper(I) C9H11Cu
707007 (1,10-Phenanthroline)bis(triphenylphosphine)copper(I) nitrate dichloromethane adduct 95%  
CDS000384 Phthalocyanine green AldrichCPR C32Cl16CuN8
346276 Tetrakis(acetonitrile)copper(I) hexafluorophosphate 97% C8H12CuF6N4P
677892 Tetrakis(acetonitrile)copper(I) tetrafluoroborate 97% Green Alternative C8H12BCuF4N4
685038 Tetrakisacetonitrile copper(I) triflate C9H12CuF3N4O3S
734527 Tetrakis(pyridine)copper(II) triflate 95% C22H20CuF6N4O6S2