Nucleobase, Nucleoside and Nucleotide Derivatives

Various nucleoside analogs have found use in basic research and as drug and drug candidates such as the antivirals Acyclovir and azidothymidine (AZT). Sigma-Aldrich offers a variety of key building blocks and intermediates for use in the development of nucleoside and nucleotide analogs and oligonucleotide synthesis.

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A26209 Adenosine 5′-triphosphate disodium salt hydrate 99% C10H14N5Na2O13P3 · xH2O
496812 7-Allyl-7,8-dihydro-8-oxoguanosine 95% C13H17N5O6
T341967   9-Allylimuran AldrichCPR C12H11N7O2S
T341819   8-(N-Aminoethanol)-adenine AldrichCPR C7H10N6O
858412 (−)-2-Amino-6-mercaptopurine riboside hydrate 98% C10H13N5O4S · xH2O
586846 N-Benzoyladenosine 97% C17H17N5O5
326151 N4-Benzoylcytidine 99% C16H17N3O6
T341916   8-N-Benzoylpiperazinylhypoxanthine AldrichCPR C16H16N6O2
13155 N6-Benzyladenosine ≥99.0% C17H19N5O4
T342033   8-Benzylaminoinosine AldrichCPR C17H19N5O5
T341983   8-(N-Benzylpiperazinyl)-inosine AldrichCPR C21H26N6O5
T341703   8-Benzylthioadenine AldrichCPR C12H11N5S
858463 8-Bromoadenosine 3′,5′-cyclic monophosphate sodium salt monohydrate 98% C10H10BrN5NaO6P · H2O
T341711   8-Bromo-3-(2′,3′-dioxypropyl)-adenine AldrichCPR C8H10N5O2Br
T341738   8-Bromo-9-(2′,3′-dioxypropyl)-adenine AldrichCPR C8H10N5O2Br
766011 8-Bromoinosine 95% C10H11BrN4O5
850187 5-Bromouridine 98% C9H11BrN2O6
T341924   8-Carboxymethylthiohypoxanthine AldrichCPR C7H6N4O3S
766739 5′-Chloro-2′,3′-isopropylidene adenosine 97% C13H16ClN5O3
713465 6-Chloro-3-methyluracil ≥98% C5H5ClN2O2
T342076   6-Chloro-8-N-morpholino-3-(2′,3′-dioxypropyl)-purine AldrichCPR C12H16N5O3Cl
T342068   6-Chloro-8-N-morpholinopurine AldrichCPR C9H10ClN5O
T341932   9-Cyanoethylhypoxanthine AldrichCPR C8H7N5O
C122106 Cytidine 99% C9H13N3O5
30270 Cytidine ≥99.0% (HPLC) C9H13N3O5
852198 2′-Deoxyadenosine 5′-monophosphate monohydrate 98% C10H14N5O6P · H2O
854980 2′-Deoxycytidine hydrate ≥99% (HPLC) C9H13N3O4 · xH2O
361275 3′-Deoxy-3′-fluorothymidine 97% C10H13FN2O4
854999 2′-Deoxyguanosine hydrate 99% C10H13N5O4 · xH2O
852228 2′-Deoxyguanosine 5′-monophosphate disodium salt hydrate ≥98% C10H12N5Na2O7P · xH2O
766755 2,6-Diaminopurine-9-arabinoside 97% C10H14N6O4
T341835   6-Diethyladenosine AldrichCPR C14H21N5O4
T341851   1-(2,3-Dihydroxypropyl)-5-fluorocytosine AldrichCPR C7H10FN3O3
T341746   3-(2′,3′-Dioxypropyl)-adenine AldrichCPR C8H11N5O2
T341754   9-(2′,3′-Dioxypropyl)-adenine AldrichCPR C8H11N5O2
T341762   3-(2,3-Dioxypropyl)-8-N-methylpiperazinyladenine HCl AldrichCPR C13H21N7O2 · HCl
656402 2-Fluoroadenosine 97% C10H12FN5O4
543020 5-Fluorocytidine 97% C9H12FN3O5
656399 2-Fluoro-2′-deoxyadenosine 96% C10H12FN5O3
T341991   8-(2-Hydoxyethylpiperazinyl)inosine AldrichCPR C16H24N6O6
663115 2-Iodoadenosine 97% C10H12IN5O4
I22404 2′,3′-O-Isopropylideneadenosine 98% C13H17N5O4
T341770   8-Mercapto-3-(2′.3′-dioxypropyl)-adenine AldrichCPR C8H11N5O2S
T342084   6-Mercapto-9-(2-cyanoethyl)-purine AldrichCPR C8H7N5S
T341789   8-Mercapto-9-(2′,3′-dioxypropyl)-adenine AldrichCPR C8H11N5O2S
T342009   8-Mercaptoinosine AldrichCPR C10H12N4O5S
T342092   6-Mercapto-9-(methylpropionate)-purine AldrichCPR C9H10N4O2S
T341908   8-N-(N′-Methylpiperazino)-guanosine HCl AldrichCPR C15H23N7O5 · HCl
T341797   8-Methylthio-3-(2′,3′-dioxypropyl)-adenine AldrichCPR C9H13N5O2S
M8905 5-Methyluridine powder C10H14N2O6
535893 5-Methyluridine 97% C10H14N2O6
T341800   8-Morpholinoadenine AldrichCPR C9H12N6O
T341886   8-N-Morpholinoguanine AldrichCPR C9H12N6O2
T341894   8-Morpholinoguanosine AldrichCPR C14H20N6O6
T341940   8-N-Morpholinohypoxanthine AldrichCPR C9H11N5O2
T342017   8-Morpholinoinosine AldrichCPR C14H19N5O6
T342106   8-N-Morpholino-6-mercaptopurine AldrichCPR C9H11N5OS
T341843   1-Oxoadenosine AldrichCPR C10H13N5O5
T342114   6-Oxo-8-mercapto-9-(2-cyanoethyl)-purine AldrichCPR C8H7N5OS
T342041   8-N-Piperadinylinosine AldrichCPR C15H21N5O5
T341959   8-N-Piperazinylhypoxanthine AldrichCPR C9H12N6O
T342025   8-N-Piperazinylinosine AldrichCPR C14H20N6O5
T341975   9-Propargylimuran AldrichCPR C12H9N7O2S
T341878 1-Propionitrile-5-fluorocytosine AldrichCPR C7H7FN4O
850926 2′,3′,5′-Tri-O-acetylguanosine 98% C16H19N5O8