Polyamines

Polyamines, organic compounds having two or more primary amino groups, are ubiquitous compounds thought to be synthesized by and required for all life. Polyamines are essential for multiple cell functions including cell proliferation and differentiation. They play multiple roles in cell growth, survival and proliferation. Changes in polyamine levels have been associated with aging and diseases. Polyamines play a role in plant development and physiology, cancer therapy, autoimmune diseases, and are a possible target for vascular diseases and antibiotics. Polyamines have also been involved in stress resistance. On the other hand, polyamines are increased in cancer cells and are a target for potential chemotherapeutic agents. Polyamines consist of positively charged ions that can interact with negatively charged molecules such as DNA, RNA and proteins. Polyamines as polycations can interact with negatively charged phosphate groups and have shown to aid in the crystallization of proteins for structure determination. Polyamines are commonly reacted with polyfunctional epoxides to give cross-linked polymers.

Learn More about Polyamines
Crosslinking Agents and Additives for Epoxides
Preparation of Chiral Diamines by the Diaza-Cope Rearrangement (DCR)

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E1521 Ethylenediamine BioXtra C2H8N2
391085 Ethylenediamine purified by redistillation, ≥99.5% C2H8N2
15068 Ethylenediamine solution technical, 75-80% C2H8N2
117498 1,2-Diaminopropane 99% C3H10N2
D23602 1,3-Diaminopropane ≥99% C3H10N2
127019 N-Methylethylenediamine 95% C3H10N2
32790 1,4-Diaminobutane puriss., ≥99.0% (GC) C4H12N2
32791 1,4-Diaminobutane purum, ≥98.0% (GC) C4H12N2
D13208 1,4-Diaminobutane 99% C4H12N2
65690 3-(Methylamino)propylamine technical, ≥97.0% (GC) C4H12N2
D157805 N,N′-Dimethylethylenediamine 99% C4H12N2
270032 N,N′-Dimethylethylenediamine 85% C4H12N2
39030 N,N-Dimethylethylenediamine ≥98.0% (GC) C4H12N2
D158003 N,N-Dimethylethylenediamine 95% C4H12N2
127000 N-Ethylethylenediamine 98% C4H12N2
127027 N-Methyl-1,3-diaminopropane 98% C4H12N2
588180 1-Dimethylamino-2-propylamine 98% C5H14N2
39370 1-Dimethylamino-2-propylamine purum, ≥97.0% (GC) C5H14N2
39380 3-(Dimethylamino)-1-propylamine purum, ≥98.0% (GC) C5H14N2
D145009 3-(Dimethylamino)-1-propylamine 99% C5H14N2
33211 Cadaverine purum, ≥97.0% (GC) C5H14N2
D22606 Cadaverine 95% C5H14N2
14790 N,N,N′,N′-Tetramethyldiaminomethane purum, ≥97.0% (GC) C5H14N2
T21407 N,N,N′,N′-Tetramethyldiaminomethane 99% C5H14N2
127124 N,N,N′-Trimethylethylenediamine 97% C5H14N2
I22102 N-Isopropylethylenediamine 98% C5H14N2
308145 N-Propylethylenediamine ≥97% C5H14N2
690023 2-(Aminomethyl)-2-methyl-1,3-propanediamine trihydrochloride ≥95.0% (NT) C5H15N3 · 3HCl
127159 N-(2-Aminoethyl)-1,3-propanediamine 97% C5H15N3
14792 Bis(dimethylamino)methylsilane ≥95.0% (GC) C5H16N2Si
777552 1,2-Diamino-5-bromo-3-chlorobenzene 97% C6H6BrClN2
714410 3,5-Dichloro-1,2-diaminobenzene 97% C6H6Cl2N2
D71607 4,5-Dichloro-o-phenylenediamine 97% C6H6Cl2N2
36214 4,5-Dichloro-o-phenylenediamine technical, ≥95.0% (AT) C6H6Cl2N2
640441 4-Bromo-1,2-diaminobenzene 97% C6H7BrN2
125172 4-Chloro-1,3-diaminobenzene 97% C6H7ClN2
541532 4-Fluoro-1,3-diaminobenzene 95% C6H7FN2
N21200 2-Nitro-1,4-phenylenediamine 95% C6H7N3O2
73620 2-Nitro-1,4-phenylenediamine technical, ≥95.0% (NT) C6H7N3O2
N21308 3-Nitro-1,2-phenylenediamine 98% C6H7N3O2
108898 4-Nitro-o-phenylenediamine 98% C6H7N3O2
78420 m-Phenylenediamine purum, ≥99.0% (T) C6H8N2
P23954 m-Phenylenediamine flakes, ≥99% C6H8N2
78422 m-Phenylenediamine technical, ≥98.0% (NT) C6H8N2
P23938 o-Phenylenediamine flaked, 99.5% C6H8N2
78429 p-Phenylenediamine ≥99.0% (GC/NT) C6H8N2
78430 p-Phenylenediamine technical, ≥97.0% (GC/NT) C6H8N2
695106 p-Phenylenediamine sublimed, ≥99% C6H8N2
726184 trans-4-Cyclohexene-1,2-diamine dihydrochloride ≥98.0% C6H12N2 · 2HCl
398160 Hexamethylenetetramine ACS reagent, ≥99.0% C6H12N4
H11300 Hexamethylenetetramine ReagentPlus®, 99% C6H12N4
270016 (±)-trans-1,2-Diaminocyclohexane 99% C6H14N2
132551 1,2-Diaminocyclohexane, mixture of cis and trans 99% C6H14N2
307467 cis-1,2-Diaminocyclohexane 97% C6H14N2
32851 trans-1,4-Diaminocyclohexane ≥98.0% (GC) C6H14N2
H11696 Hexamethylenediamine 98% C6H16N2
422002 Hexamethylenediamine technical grade, 70% C6H16N2
126942 N,N′-Diethylethylenediamine 95% C6H16N2
411019 N,N,N′,N′-Tetramethylethylenediamine ≥99.5%, purified by redistillation C6H16N2
332550 N,N,N′-Trimethyl-1,3-propanediamine 96% C6H16N2
112720 N,N-Diethylethylenediamine 99% C6H16N2
126985 N,N-Dimethyl-N′-ethylethylenediamine 98% C6H16N2
480592 N-Butylethylenediamine 97% C6H16N2
305545 N-Isopropyl-1,3-propanediamine 95% C6H16N2
308153 N-Propyl-1,3-propanediamine 99% C6H16N2
I7006 Bis(3-aminopropyl)amine C6H17N3
14520 Bis(3-aminopropyl)amine purum, ≥97.0% (GC) C6H17N3
I1006 Bis(3-aminopropyl)amine 98% C6H17N3
570141 Tris(dimethylamino)chlorosilane ≥99% C6H18ClN3Si
90460 Triethylenetetramine ≥97.0% (T) C6H18N4
132098 Triethylenetetramine technical grade, 60% C6H18N4
259535 Triethylenetetramine hydrate 98% C6H18N4 · xH2O
656003 3-Bromo-4,5-diaminobenzotrifluoride 97% C7H6BrF3N2
540439 2-(Trifluoromethyl)-1,4-phenylenediamine 97% C7H7F3N2
196975 5-(Trifluoromethyl)-1,3-phenylenediamine 98% C7H7F3N2
272361 2,3-Diaminotoluene 97% C7H10N2
348015 2-Aminobenzylamine 98% C7H10N2
339938 3,4-Diaminotoluene 99%, purified by sublimation C7H10N2
D26024 3,4-Diaminotoluene 97% C7H10N2
368466 4-Aminobenzylamine 99% C7H10N2
33360 4-Methyl-m-phenylenediamine technical, ≥98.0% (NT) C7H10N2
33380 4-Methyl-o-phenylenediamine purum, ≥98.0% (NT) C7H10N2
398985 N-Methyl-1,2-phenylenediamine 97% C7H10N2
D17408 1,7-Diaminoheptane 98% C7H18N2
549975 3-(Diethylamino)propylamine ≥99% C7H18N2
138428 N,N′-Diethyl-1,3-propanediamine 97% C7H18N2
227412 N,N,2,2-Tetramethyl-1,3-propanediamine 97% C7H18N2
549983 N,N,N′,N′-Tetramethyl-1,3-propanediamine ≥99% C7H18N2
31930 N,N-Diethyl-1,3-propanediamine purum, ≥98.0% (GC) C7H18N2
308099 N,N-Diethyl-N′-methylethylenediamine 97% C7H18N2
188441 3,3′-Diamino-N-methyldipropylamine 96% C7H19N3
422355 N1-Isopropyldiethylenetriamine technical grade, 75% C7H19N3
221058 Tris(dimethylamino)methane 97% C7H19N3
333131 N,N′-Bis(2-aminoethyl)-1,3-propanediamine 97% C7H20N4
705985 Methyl 3,4-diaminobenzoate 97% C8H10N2O2
741493 1,2-Diamino-3,5-dimethylbenzene 96% C8H12N2
D176605 4,5-Dimethyl-1,2-phenylenediamine 98% C8H12N2
123056 4-(2-Aminoethyl)aniline 97% C8H12N2
33421 m-Xylylenediamine purum, ≥98.0% (NT) C8H12N2
X1202 m-Xylylenediamine 99% C8H12N2
193992 N,N-Dimethyl-p-phenylenediamine 97% C8H12N2
07760 N,N-Dimethyl-p-phenylenediamine technical, ≥95.0% (GC) C8H12N2
P24152 N-Phenylethylenediamine 98% C8H12N2
690015 o-Xylylenediamine 95% C8H12N2
711462 o-Xylylenediamine dihydrochloride ≥98% C8H12N2 · 2HCl
633089 trans-N,N′-Dimethylcyclohexane-1,2-diamine 97% C8H18N2
518840 trans-N,N,N′,N′-Tetramethyl-2-butene-1,4-diamine 98% C8H18N2
D22401 1,8-Diaminooctane 98% C8H20N2
D161101 N,N′-Dimethyl-1,6-hexanediamine 98% C8H20N2
14740 N,N,N′,N′-Tetramethyl-1,3-butanediamine ≥99.0% C8H20N2
127116 N,N,N′-Triethylethylenediamine 98% C8H20N2
480606 N-Hexylethylenediamine 97% C8H20N2
667609 Bis[2-(N,N-dimethylamino)ethyl] ether 97% C8H20N2O
518832 N,N-Diethyldiethylenetriamine 98% C8H21N3
550019 N,N-Dimethyldipropylenetriamine 99% C8H21N3
239399 1,2-Bis(3-aminopropylamino)ethane technical grade, 94% C8H22N4
T11509 Tetraethylenepentamine technical grade C8H23N5
92715 2,4,6-Trimethyl-m-phenylenediamine purum, ≥97.0% (GC/NT) C9H14N2
462292 N-Benzylethylenediamine 97% C9H14N2
693855 N-Tosylethylenediamine 97% C9H14N2O2S
C108057 N-Cyclohexyl-1,3-propanediamine 99% C9H20N2
CDS009225 tert-Butyl 2-aminoethyl(ethyl)carbamate hydrochloride AldrichCPR C9H21ClN2O2
722650 2,2,4(2,4,4)-Trimethyl-1,6-hexanediamine 99% C9H22N2
A48806 2-Amino-5-diethylaminopentane 97% C9H22N2
127175 N,N,N′,N′-Tetraethylmethanediamine 97% C9H22N2
384216 tert-Butoxy bis(dimethylamino)methane C9H22N2O
20425 tert-Butoxy bis(dimethylamino)methane technical C9H22N2O
690228 N,N-Bis[3-(methylamino)propyl]methylamine 98% C9H23N3
404810 N,N′-Bis(3-aminopropyl)-1,3-propanediamine technical grade, 90% C9H24N4
463531 Tris[2-(methylamino)ethyl]amine 97% C9H24N4
667617 1,4-Diaminonaphthalene 97% C10H10N2
D21200 1,5-Diaminonaphthalene 97% C10H10N2
D21405 1,8-Diaminonaphthalene 99% C10H10N2
33180 1,8-Diaminonaphthalene technical, ≥95.0% (HPLC) C10H10N2
32975 2,3,5,6-Tetramethyl-p-phenylenediamine purum, ≥99.0% (NT) C10H16N2
T7394 N,N,N′,N′-Tetramethyl-p-phenylenediamine 99%, powder C10H16N2
261513 N,N-Diethyl-p-phenylenediamine 97% C10H16N2
D19605 1,8-Diamino-p-menthane, mixture of cis and trans isomers technical grade, 85% C10H22N2
469564 cis-1,8-Diamino-p-menthane 98% C10H22N2
32880 1,10-Diaminodecane purum, ≥98.0% (GC) C10H24N2
D14204 1,10-Diaminodecane 97% C10H24N2
447005 N,N′-Di-tert-butylethylenediamine 98% C10H24N2
493775 N,N′-Dimethyl-1,8-octanediamine 98% C10H24N2
127078 N,N,N′,N′-Tetraethylethylenediamine 98% C10H24N2
92892 4,7,10-Trioxa-1,13-tridecanediamine purum, ≥98.0% (NT) C10H24N2O3
348554 3,3′-Iminobis(N,N-dimethylpropylamine) 97% C10H25N3
292753 Pentaethylenehexamine technical grade C10H28N6
127191 N′-Benzyl-N,N-dimethylethylenediamine 95% C11H18N2
565954 4-tert-Butyl-2,6-diaminoanisole 97% C11H18N2O
701688 1-(Boc-amino)-1-aminomethyl cyclopentane 95% C11H22N2O2
CDS007803 1-N-Boc-1,2-cis-cyclohexyldiamine AldrichCPR C11H22N2O2
D45606 3-(Dibutylamino)propylamine 98% C11H26N2
327522 N-(4-Chlorophenyl)-1,2-phenylenediamine 97% C12H11ClN2
727601 2,2′-Biphenyldiamine ≥96.5% (GC) C12H12N2
07900 N-Phenyl-o-phenylenediamine purum, ≥98.0% (NT) C12H12N2
P28352 N-Phenyl-o-phenylenediamine 98% C12H12N2
241393 N-Phenyl-p-phenylenediamine 98% C12H12N2
470716 2,2′-Oxydianiline 98% C12H12N2O
32925 4,4′-Oxydianiline puriss., zone refined, ≥99.0% (GC) C12H12N2O
247278 4,4′-Oxydianiline zone-refined, purified by sublimation, ≥99% C12H12N2O
248398 4,4′-Oxydianiline purified by sublimation, 99% C12H12N2O
516805 4,4′-Oxydianiline 97% C12H12N2O
32741 3,3′-Diaminobenzidine purum, ≥98.0% (CHN) C12H14N4
D12384 3,3′-Diaminobenzidine 99% C12H14N4
709700 2-(Boc-amino)benzylamine C12H18N2O2
D16401 1,12-Diaminododecane 98% C12H28N2
421960 Bis(hexamethylene)triamine high purity C12H29N3
421987 Bis(hexamethylene)triamine technical grade, 40% C12H29N3
424072 N,N,N′,N′-Tetraethyldiethylenetriamine technical grade, 90% C12H29N3
366404 1,1,4,7,10,10-Hexamethyltriethylenetetramine 97% C12H30N4
D17106 2,7-Diaminofluorene >97% C13H12N2
655449 3,4′-Diaminodiphenylmethane 95% C13H14N2
32950 4,4′-Diaminodiphenylmethane ≥97.0% (GC) C13H14N2
709662 α-(Boc-amino)phenethylamine C13H20N2O2
D22908 9,10-Diaminophenanthrene 97% C14H12N2
32784 4,4′-Ethylenedianiline technical, ≥95% (NT) C14H16N2
458511 meso-1,2-Diphenylethylenediamine 98% C14H16N2
D27004 N,N′-Diphenylethylenediamine 98% C14H16N2
422827 N-Methyl-4,4′-methylenedianiline 97% C14H16N2
89583 o-Tolidine technical, ≥97.0% (calc. based on dry substance, NT) C14H16N2
14795 N,N,N′,N′-Tetramethyl-1,8-naphthalenediamine purum, ≥99.0% (NT) C14H18N2
158496 Proton-sponge® 99% C14H18N2
463434 2-Amino-N-cyclohexyl-N-methylbenzylamine 98% C14H22N2
689920 2,4,6-Triethyl-1,3,5-benzenetrimethanamine trihydrochloride 98% C15H27N3 · 3HCl
369500 4,4′-Methylenebis(2-methylcyclohexylamine), mixture of isomers 99% C15H30N2
431702 N,N′,N′′-Trimethylbis(hexamethylene)triamine 97% C15H35N3
645095 Tris[2-(isopropylamino)ethyl]amine 90% C15H36N4
D35201 N,N′-Dibenzylethylenediamine 97% C16H20N2
233544 4-Dodecylaniline 97% C18H31N
631698 1,1′-Binaphthyl-2,2′-diamine 96% C20H16N2
521981 N,N′,N′′-Trihexyldiethylenetriamine 99.99% C22H49N3
437913 4,4′-(9-Fluorenylidene)dianiline 99% C25H20N2
693960 N,N′-Bis(2,6-diisopropylphenyl)ethylenediamine 95% C26H40N2
64875 Bis(dimethylamino)methoxymethane technical