Thiocyanates/Isothiocyanates

Thiocyanates (-SCN) and isothiocyanates (-NCS) are resonance stabilized such that the sulfur or nitrogen can act as a nucleophile, a metal ligand, and serve as linkage isomers. Isothiocyanate derivatives, such as benzyl isothiocyanate and allyl isothiocyanate, have been shown to serve as cancer chemopreventive agents and exhibit antimicrobial activities, respectively. Sigma-Aldrich offers an extensive variety of alkyl and aryl thiocyanate and isothiocyanate salts and derivatives incorporating sodium, potassium, barium, lead, ammonium, and benzyl/phenyl, as well as halogenated compounds for use in coupling methodologies, such as Suzuki-Miyaura cross-coupling reactions.

Learn More about Thiocyanates and Isothiocyanates
Selectfluor®
Enantiomeric Purities of Pharmaceuticals Using Carbohydrate-based Isothiocyanates
Enantiomeric Purities of Amino Acids Using Carbohydrate-Based Isothiocyanates

Product #

Image

Description

Molecular Formula

Add to Cart

207799 Potassium thiocyanate ACS reagent, ≥99.0% CKNS
467871 Sodium thiocyanate ≥99.99% trace metals basis CNNaS
251410 Sodium thiocyanate ACS reagent, ≥98.0% CNNaS
431354 Ammonium thiocyanate 99.99% trace metals basis CH4N2S
221988 Ammonium thiocyanate ACS reagent, ≥97.5% CH4N2S
A7149 Ammonium thiocyanate powder CH4N2S
339156 Barium thiocyanate hydrate C2BaN2S2 · xH2O
208302 Lead(II) thiocyanate 99.5% trace metals basis C2N2PbS2
105112 Chloromethyl thiocyanate 97% C2H2ClNS
112771 Methyl isothiocyanate 97% C2H3NS
722197 Methyl thiocyanate 97% C2H3NS
E33904 Ethyl isothiocyanate 97% C3H5NS
308951 Ethyl thiocyanate 97% C3H5NS
196126 Ethoxycarbonyl isothiocyanate 98% C4H5NO2S
377430 Allyl isothiocyanate contains BHT as stabilizer, 95% C4H5NS
709352 Cyclopropyl isothiocyanate 97% C4H5NS
709123 2-Methoxyethyl isothiocyanate 95% C4H7NOS
476013 Isopropyl isothiocyanate 97% C4H7NS
253944 Propyl isothiocyanate 98% C4H7NS
230766 (Trimethylsilyl)isothiocyanate 99% C4H9NSSi
279692 Ethyl isothiocyanatoacetate 97% C5H7NO2S
CDS000106 4-Isothiocyanato-1-butene AldrichCPR C5H7NS
571105 Methallyl isothiocyanate technical C5H7NS
CDS000456 2-Isothiocyanatobutane AldrichCPR C5H9NS
253790 Butyl isothiocyanate 99% C5H9NS
CDS001467 Isobutyl isothiocyanate AldrichCPR C5H9NS
251852 tert-Butyl isothiocyanate 99% C5H9NS
708909 1,4-Butane diisothiocyanate 97% C6H8N2S2
CDS000100 5-Isothiocyanato-1-pentene AldrichCPR C6H9NS
CDS000716 Cyclopentyl isothiocyanate AldrichCPR C6H9NS
630004 2,4,5-Trichlorophenyl isothiocyanate 97% C7H2Cl3NS
476005 2,3-Dichlorophenyl isothiocyanate 98% C7H3Cl2NS
414875 2,4-Dichlorophenyl isothiocyanate 95% C7H3Cl2NS
474932 2,5-Dichlorophenyl isothiocyanate 98% C7H3Cl2NS
475890 2,6-Dichlorophenyl isothiocyanate 97% C7H3Cl2NS
474835 2,4-Difluorophenyl isothiocyanate 98% C7H3F2NS
474843 2,5-Difluorophenyl isothiocyanate 97% C7H3F2NS
511781 2,6-Difluorophenyl isothiocyanate 98% C7H3F2NS
253154 2-Bromophenyl isothiocyanate 98% C7H4BrNS
253162 3-Bromophenyl isothiocyanate 97% C7H4BrNS
270202 4-Bromophenyl isothiocyanate 97% C7H4BrNS
253766 3-Chlorophenyl isothiocyanate 98% C7H4ClNS
26001 4-Chlorophenyl isothiocyanate purum, ≥98.0% (AT) C7H4ClNS
253782 4-Chlorophenyl isothiocyanate 99% C7H4ClNS
253693 2-Fluorophenyl isothiocyanate 98% C7H4FNS
F14351 3-Fluorophenyl isothiocyanate 99% C7H4FNS
128406 4-Fluorophenyl isothiocyanate 98% C7H4FNS
475939 3-Iodophenyl isothiocyanate 97% C7H4INS
857823 4-Sulfophenyl isothiocyanate sodium salt monohydrate technical grade C7H4NNaO3S2 · H2O
487376 3-Nitrophenyl isothiocyanate 98% C7H4N2O2S
283541 4-Nitrophenyl isothiocyanate 98% C7H4N2O2S
78780 Phenyl isothiocyanate for HPLC derivatization, the detection of alcohols and amines, ≥99.0% C7H5NS
317861 Phenyl isothiocyanate 99%, for protein sequencing C7H5NS
550647 2-Nitro-4-thiocyanatoaniline 95% C7H5N3O2S
C105406 Cyclohexyl isothiocyanate 98% C7H11NS
475912 Hexyl isothiocyanate 95% C7H13NS
CDS004007 Hexyl thiocyanate AldrichCPR C7H13NS
CDS003562 4-bromo-2-(trifluoromethoxy)phenyl isothiocyanate AldrichCPR C8H3BrF3NOS
474886 2-Chloro-5-(trifluoromethyl)phenyl isothiocyanate 98% C8H3ClF3NS
525421 4-Fluoro-3-(trifluoromethyl)phenyl isothiocyanate 98% C8H3F4NS
525359 4-(Trifluoromethoxy)phenyl isothiocyanate 97% C8H4F3NOS
476099 4-(Trifluoromethyl)phenyl isothiocyanate 97% C8H4F3NS
525375 3-(Trifluoromethylthio)phenyl isothiocyanate 97% C8H4F3NS2
496642 3-Cyanophenyl isothiocyanate 98% C8H4N2S
484660 4-Cyanophenyl isothiocyanate 98% C8H4N2S
568937 1,3-Phenylene diisothiocyanate 97% C8H4N2S2
261653 Benzoyl isothiocyanate 98% C8H5NOS
68357 4-(Bromomethyl)phenyl isothiocyanate ≥98.0% C8H6BrNS
474983 2-Methoxy-4-nitrophenyl isothiocyanate 95% C8H6N2O3S
253707 2-Methoxyphenyl isothiocyanate 98% C8H7NOS
475955 3-Methoxyphenyl isothiocyanate 98% C8H7NOS
CDS016664 4-hydroxy-3-methylphenyl thiocyanate AldrichCPR C8H7NOS
247189 4-Methoxyphenyl isothiocyanate 98% C8H7NOS
252492 Benzyl isothiocyanate 98% C8H7NS
13929 Benzyl thiocyanate ≥95.0% (GC) C8H7NS
318264 m-Tolyl isothiocyanate 97% C8H7NS
253715 p-Tolyl isothiocyanate 97% C8H7NS
468509 4-(Methylthio)phenyl isothiocyanate 98% C8H7NS2
530859 exo-2-Norbornylisothiocyanate 96% C8H11NS
591262 Cyclohexylmethyl isothiocyanate 97% C8H13NS
15524 N-Boc-2-isothiocyanatoethylamine ≥98.0% (GC) C8H14N2O2S
560510 3-(Diethylamino)propyl isothiocyanate 97% C8H16N2S
468517 3,5-Bis(trifluoromethyl)phenyl isothiocyanate 98% C9H3F6NS
559768 4-Methyl-3-(trifluoromethyl)phenyl isothiocyanate 98% C9H6F3NS
568929 Tolylene-2,4-diisothiocyanate 97% C9H6N2S2
591378 2-(4-Chlorophenethyl)isothiocyanate 97% C9H8ClNS
474967 2-Methoxy-5-methylphenyl isothiocyanate 98% C9H9NOS
476439 2,6-Dimethylphenyl isothiocyanate 98% C9H9NS
475971 4-Ethylphenyl isothiocyanate 98% C9H9NS
253731 Phenethyl isothiocyanate 99% C9H9NS
15530 N-Boc-3-isothiocyanatopropylamine ≥97.0% (GC) C9H16N2O2S
CDS003580 5-indanyl isothiocyanate AldrichCPR C10H9NS
511854 3,4,5-Trimethoxyphenyl isothiocyanate 98% C10H11NO3S
15523 N-Boc-4-isothiocyanatobutylamine ≥97.0% C10H18N2O2S
N4525 1-Naphthyl isothiocyanate 95% C11H7NS
CDS006959 4-tert-Butylphenyl isothiocyanate AldrichCPR C11H13NS
143367 1-Adamantyl isothiocyanate 99% C11H15NS
59814 tert-Butyl 3-isothiocyanatobenzoate ≥97.0% (HPLC) C12H13NO2S
59816 tert-Butyl 4-isothiocyanatobenzoate ≥97.0% (HPLC) C12H13NO2S
15521 N-Boc-4-isothiocyanatoaniline ≥98.0% (HPLC) C12H14N2O2S
CDS004931 3-biphenyl isothiocyanate AldrichCPR C13H9NS
591696 Benzhydryl isothiocyanate 97% C14H11NS
569127   4,4′-Methylenebis(phenyl isothiocyanate) C15H10N2S2
02977 2-(4-Isothiocyanatophenoxy)ethyl tosylate ≥98.0% (TLC) C16H15NO4S2
591904 Trityl isothiocyanate 95% C20H15NS