Lactams

Lactams are cyclic amides of varying ring sizes, such as alpha, beta, and gamma lactams. β-lactams are notable antibiotics; however, lactam ring derivatives exhibit additional pharmacological effects. β-Lactam compounds demonstrated biological activity as inhibitors of a wide range of enzymes, including HFAAH inhibitors, HDAC inhibitors, anti-inflammatory drugs (tryptase inhibitors), Cathepsin K inhibitors, and vasopressin inhibitors, as well as anticancer and antitubercular activities.

Learn More about Lactams
Chiral Dirhodium Carboxamidates: Catalysts for Highly Enantioselective Syntheses of Lactones and Lactams
New Methods in the Formation of Macrocyclic Lactams and Lactones of Biological Interest
Exploiting Grubbs Catalysts with Novel Reactivity
Cinchona Alkaloids

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328464 2-Azetidinone 98% C3H5NO
272159 4-Acetoxy-2-azetidinone 98% C5H7NO3
V209 δ-Valerolactam 98% C5H9NO
331910 2-Azabicyclo[2.2.1]hept-5-en-3-one 98% C6H7NO
C2204 ε-Caprolactam 99% C6H11NO
41336 DL-α-Amino-ε-caprolactam hydrochloride ≥99.0% C6H12N2O · HCl
CBR01818 (1R*,5S*)-3,6-Diazabicyclo[3.2.2]nonan-7-one AldrichCPR C7H12N2O
A94638 1-Aza-2-cyclooctanone 98% C7H13NO
224766 N-Methylcaprolactam 99% C7H13NO
CBR00416 2-Azaspiro[4.4]nonan-3-one AldrichCPR C8H13NO
283010 N-Acetylcaprolactam 99% C8H13NO2
123277 2-Azacyclononanone 98% C8H15NO
ADE000851 6-Methyl-3,4-dihydro-1,8-naphthyridin-2(1H)-one AldrichCPR C9H10N2O
ADE000843 5-Methoxy-3,4-dihydro-1,7-naphthyridin-2(1H)-one AldrichCPR C9H10N2O2
ADE000841 5-Methoxy-3,4-dihydro-1,8-naphthyridin-2(1H)-one AldrichCPR C9H10N2O2
CBR01714 2,9-Diazaspiro[5.5]undecan-3-one dihydrochloride AldrichCPR C9H18Cl2N2O
CDS020594 7-Hydroxy-2,3,4,5-tetrahydro-benzo[c]azepin-1-one AldrichCPR C10H11NO2
403164 4-Azatricyclo[4.3.1.13,8]undecan-5-one 98% C10H15NO
CBR00301 2-Azaspiro[4.6]undecan-3-one AldrichCPR C10H17NO
CDS004715 6-fluoro-4-chromanone hydantoin AldrichCPR C11H9FN2O3
562386 1-Benzyl-3-trifluoromethyl-2-azetidinone C11H10F3NO
719706 N-Boc-ε-caprolactam 97% C11H19NO3
A94654 12-Aminododecanolactam 98% C12H23NO
61600 Laurolactam puriss., ≥99.0% (N) C12H23NO
CDS019845 4-Phenyl-2,7-diazaspiro[4.5]decan-1-one hydrochloride AldrichCPR C14H19ClN2O