Benzodioxanes

Benzodioxane derivatives, bicyclic heterocyclic systems consisting of a benzene ring fused to a heterocyclic dioxane ring, represent a series of synthetic and natural compounds of considerable medicinal importance. Compounds containing the dioxane or the 1,4-benzodioxane moiety exhibit various biological activities such as antihepatotoxic (hepatoprotective), α-adrenergic blocking agent activity, anti-inflammatory, antigrastic, spasmolytic, antipsychotic, anxiolytic, and D2 antagonist/5-HT1A partial agonist activity.

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CDS013917 5-bromo-2,2-difluoro-1,3-benzodioxole AldrichCPR C7H3BrF2O2
    • CDS003013 2,2-Difluoro-1,3-benzodioxole-4-carbaldehyde AldrichCPR C7H4F2O2
    • 739383 2,2-Difluoro-1,3-benzodioxole-4-carboxaldehyde 97% C7H4F2O2
    • CDS015940 1,3-benzodioxole-5-sulfonyl chloride AldrichCPR C7H5ClO4S
    • CDS003005 5-Iodo-1,3-benzodioxole AldrichCPR C7H5IO2
    • CBR00760 1,3-Benzodioxol-5-ylhydrazine hydrochloride AldrichCPR C7H9ClN2O2
    • 738913 6-Bromo-1,3-benzodioxole-5-carbonitrile 97% C8H4BrNO2
    • CDS011641 7-chloro-1,3-benzodioxole-5-carbaldehyde AldrichCPR C8H5ClO3
    • 538523 6-Bromo-1,4-benzodioxane 97% C8H7BrO2
    • CDS016454 (6-bromo-1,3-benzodioxol-5-yl)methanol AldrichCPR C8H7BrO3
    • CDS013599 6-iodo-2,3-dihydro-1,4-benzodioxine AldrichCPR C8H7IO2
    • 548790 6-Nitro-1,4-benzodioxane 97% C8H7NO4
    • 179000 Benzo-1,4-dioxane 97% C8H8O2
    • CDS019999 2,3-Dihydro-1,4-benzodioxin-5-ol AldrichCPR C8H8O3
    • 193232 1,4-Benzodioxan-6-amine ≥98% C8H9NO2
    • CDS005018 5-amino-1,4-benzodioxane AldrichCPR C8H9NO2
    • CBR00391 (6-Methoxy-1,3-benzodioxol-5-yl)amine AldrichCPR C8H9NO3
    • CDS020583 2,3-Dihydro-1,4-benzodioxine-6,7-diamine AldrichCPR C8H10N2O2
    • CBR00939 2,3-Dihydro-1,4-benzodioxin-6-ylhydrazine hydrochloride AldrichCPR C8H11ClN2O2
    • CDS014400 6-fluoro-4H-1,3-benzodioxin-8-yl isocyanate AldrichCPR C9H6FNO3
    • CDS008060 7-bromo-2,3-dihydro-1,4-benzodioxine-6-carbaldehyde AldrichCPR C9H7BrO3
    • CDS006548 7-Bromo-2,3-dihydro-1,4-benzodioxine-6-carboxylic acid AldrichCPR C9H7BrO4
    • CDS013957 2,3-dihydro-1,4-benzodioxine-2-carbonyl chloride AldrichCPR C9H7ClO3
    • CDS016028 2,3-dihydro-1,4-benzodioxine-5-carbonyl chloride AldrichCPR C9H7ClO3
    • CDS013024 8-chloro-2,3-dihydro-1,4-benzodioxine-6-carbaldehyde AldrichCPR C9H7ClO3
    • CDS013002 8-chloro-2,3-dihydro-1,4-benzodioxine-6-carboxylic acid AldrichCPR C9H7ClO4
    • CDS017647 6-fluoro-4H-1,3-benzodioxine-8-carbaldehyde AldrichCPR C9H7FO3
    • CDS013659 6-fluoro-4H-1,3-benzodioxine-8-carboxylic acid AldrichCPR C9H7FO4
    • CDS019807 5-(Isocyanatomethyl)-1,3-benzodioxole AldrichCPR C9H7NO3
    • 569186   6-Isocyanato-1,4-benzodioxane 97% C9H7NO3
    • 264598 1,4-Benzodioxan-6-carboxaldehyde 98% C9H8O3
    • CDS016512 2,3-dihydro-1,4-benzodioxine-5-carbaldehyde AldrichCPR C9H8O3
    • CBR00442 6-Methyl-1,3-benzodioxole-5-carbaldehyde AldrichCPR C9H8O3
    • 561371 1,4-Benzodioxan-2-carboxylic acid 97% C9H8O4
    • 563331 1,4-Benzodioxan-5-carboxylic acid 98% C9H8O4
    • 658375 1,4-Benzodioxane-6-carboxylic acid 97% C9H8O4
    • 758108 6-Methoxy-1,3-benzodioxole-5-carbaldehyde 97% C9H8O4
    • 632643 2-Bromomethyl-1,4-benzodioxane 97% C9H9BrO2
    • CDS019440 6-(Bromomethyl)-2,3-dihydrobenzo[b][1,4]dioxine AldrichCPR C9H9BrO2
    • CDS018020 2,3-dihydro-1,4-benzodioxine-6-carbothioamide AldrichCPR C9H9NO2S
    • CDS013098 (8-chloro-2,3-dihydro-1,4-benzodioxin-6-yl)methylamine AldrichCPR C9H10ClNO2
    • CDS017552 N′-hydroxy-2,3-dihydro-1,4-benzodioxine-2-carboximidamide AldrichCPR C9H10N2O3
    • CDS014756 2,3-dihydro-1,4-benzodioxin-5-ylmethanol AldrichCPR C9H10O3
    • CDS015301 2,3-dihydro-1,4-benzodioxin-6-ylmethanol AldrichCPR C9H10O3
    • H38403 2-Hydroxymethyl-1,4-benzodioxan 97% C9H10O3
    • CDS014900 benzodioxan-2-carboxamidine hydrochloride AldrichCPR C9H11ClN2O2
    • CDS014411 2,3-dihydro-1,4-benzodioxin-6-ylmethylamine AldrichCPR C9H11NO2
    • CDS013915 2,3-dihydro-1,4-benzodioxin-5-ylmethylamine hydrochloride AldrichCPR C9H12ClNO2
    • CDS017882 1-(6,7-dichloro-2,3-dihydro-1,4-benzodioxin-5-yl)-1-ethanone AldrichCPR C10H8Cl2O3
    • CDS010773 (7-bromo-2,3-dihydro-1,4-benzodioxin-6-yl)acetic acid AldrichCPR C10H9BrO4
    • 532584 6-Chloroacetyl-1,4-benzodioxane 97% C10H9ClO3
    • CDS019717 3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1H-1,2,4-triazol-5-amine AldrichCPR C10H10N4O2
    • 179027 1,4-Benzodioxan-6-yl methyl ketone 98% C10H10O3
    • CBR01242 1-(2,3-Dihydro-1,4-benzodioxin-2-yl)ethanone AldrichCPR C10H10O3
    • 731927 1,4-Benzodioxane-6-acetic acid 97% C10H10O4
    • CDS018707 7-methoxy-2,3-dihydro-1,4-benzodioxin-6-carbaldehyde AldrichCPR C10H10O4
    • CDS009523 8-methoxy-2,3-dihydro-benzo[1,4]dioxine-6-carbaldehyde AldrichCPR C10H10O4
    • CDS012338 8-methoxy-2,3-dihydro-1,4-benzodioxine-6-carboxylic acid AldrichCPR C10H10O5
    • CDS017983 7-(Chloromethyl)-3,4-dihydro-2H-1,5-benzodioxepine AldrichCPR C10H11ClO2
    • CBR01255 2-(2,3-Dihydro-1,4-benzodioxin-2-yl)ethanol AldrichCPR C10H12O3
    • CDS012625 2-(8-chloro-2,3-dihydro-1,4-benzodioxin-6-yl)ethanamine hydrochloride AldrichCPR C10H13Cl2NO2
    • CBR01103   1-(2,3-Dihydro-1,4-benzodioxin-2-yl)ethanamine AldrichCPR C10H13NO2
    • CDS010777 1-(2,3-dihydro-1,4-benzodioxin-6-yl)ethanamine AldrichCPR C10H13NO2
    • CDS010225 2-amino-1-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-ethanol AldrichCPR C10H13NO3
    • CDS001742 1-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-ethylamine hydrochloride AldrichCPR C10H14ClNO2
    • CDS020423 2-(2,3-Dihydro-1,4-benzodioxin-6-yl)ethanamine hydrochloride AldrichCPR C10H14ClNO2
    • CDS016361 1-(1,3-benzodioxol-5-yl)-4,4,4-trifluorobutane-1,3-dione AldrichCPR C11H7F3O4
    • CDS019882 3-(1,3-Benzodioxol-5-yl)dihydro-2,5-furandione AldrichCPR C11H8O5
    • CDS005649 4-(7-Chloro-2,3-dihydro-1,4-benzodioxin-6-yl)-1,3-thiazol-2-amine AldrichCPR C11H9ClN2O2S
    • CDS016732 [(2,3-dihydro-benzo[1,4]dioxine-2-carbonyl)-amino]-acetic acid AldrichCPR C11H11NO5
    • CDS013015 5-(2,3-dihydro-1,4-benzodioxin-6-yl)-6h-1,3,4-thiadiazin-2-amine AldrichCPR C11H11N3O2S
    • 662259 Ethyl 1,4-benzodioxan-2-carboxylate 97% C11H12O4
    • CDS016959 3-(2,3-dihydro-benzo[1,4]dioxin-6-yloxy)-propionic acid AldrichCPR C11H12O5
    • CDS020223 Methyl 3-amino-3-(1,3-benzodioxol-5-yl)propanoate hydrochloride AldrichCPR C11H14ClNO4
    • CDS015359 N-(2,3-dihydro-1,4-benzodioxin-2-ylmethyl)-N-ethylamine AldrichCPR C11H15NO2
    • CDS015265 N-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)-N-ethylamine AldrichCPR C11H15NO2
    • CDS012089 2-((2,3-dihydro-1,4-benzodioxin-6-ylmethyl)amino)ethanol AldrichCPR C11H15NO3
    • CDS002282 3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1H-pyrazole-5-carboxylic acid AldrichCPR C12H10N2O4
    • CDS006842 ethyl 3,4-ethylenedioxybenzoylformate AldrichCPR C12H12O5
    • CDS017124 4,7-dimethoxy-5-(2-propanyl)-1,3-benzodioxole AldrichCPR C12H14O4
    • CDS013893 4-(2,3-dihydro-1,4-benzodioxin-6-yl)butanoic acid AldrichCPR C12H14O4
    • CDS007141 2-(2,3-Dihydro-1,4-benzodioxin-6-yl)pyrrolidine AldrichCPR C12H15NO2
    • CDS012104 N-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)prop-2-en-1-amine AldrichCPR C12H15NO2
    • CDS014603 N-2,3-dihydro-1,4-benzodioxin-6-yl-2-(ethylamino)acetamide AldrichCPR C12H16N2O3
    • CDS011785 n-2,3-dihydro-1,4-benzodioxin-6-yl-2-(ethylamino)acetamide hydrochloride AldrichCPR C12H17ClN2O3
    • CDS014553 N-(2,3-dihydro-1,4-benzodioxin-2-ylmethyl)-N-isopropyl amine AldrichCPR C12H17NO2
    • CDS015368 N-(2,3-dihydro-1,4-benzodioxin-2-ylmethyl)-N-propylamine AldrichCPR C12H17NO2
    • CDS019426 3-(1,3-Benzodioxol-5-yl)-N-(2-propynyl)acrylamide AldrichCPR C13H11NO3
    • CDS019222 N-(7-Amino-2,3-dihydro-1,4-benzodioxin-6-yl)thiophene-2-carboxamide AldrichCPR C13H12N2O3S
    • CDS005300 4-[(2,3-Dihydro-1,4-benzodioxin-2-ylmethyl)amino]-4-oxobutanoic acid AldrichCPR C13H15NO5
    • CDS007188 (R)-1,4-benzodioxan-2-carboxypiperazine AldrichCPR C13H16N2O3
    • CDS005337 N-[(1,4-benzodioxaN-2-yl)carbonyl]piperazine hydrochloride AldrichCPR C13H16N2O3
    • CDS014835 1-(2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride AldrichCPR C13H17ClN2O3
    • CDS012786 1-(2,3-dihydro-1,4-benzodioxin-6-yl)cyclopentanecarboxylic acid AldrichCPR C14H16O4
    • CDS012764 [1-(2,3-dihydro-1,4-benzodioxin-6-yl)cyclopentyl]methylamine AldrichCPR C14H19NO2
    • CDS009708 2-bromo-3′,4′-(ethylenedioxy)benzophenone AldrichCPR C15H11BrO3
    • CDS019628 2-Amino-N-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-benzamide AldrichCPR C15H14N2O3
    • CDS019599 4-Amino-N-(2,3-dihydro-1,4-benzodioxin-6-yl)benzamide AldrichCPR C15H14N2O3
    • CDS002067 1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde AldrichCPR C15H15NO3
    • CDS010807 2-(2,3-dihydro-benzo[1,4]dioxine-6-carbonyl)-benzoic acid AldrichCPR C16H12O5
    • CDS014990 (7-bromo-2,3-dihydro-1,4-benzodioxin-6-yl)(4-methylphenyl)methanone AldrichCPR C16H13BrO3
    • CDS005972 4-[(2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl)amino]benzenecarboxylic acid AldrichCPR C16H13NO5
    • CDS011601 1-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-2-phenyl-ethylamine AldrichCPR C16H17NO2
    • CDS019908 2-{[5-(2,3-Dihydro-1,4-benzodioxin-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(1H-pyrrol-2-yl)ethanone AldrichCPR C17H16N4O3S
    • CDS020562 N-[4-(Acetylamino)-3-chlorophenyl]-2-(2,3-dihydro-1,4-benzodioxin-6-ylsulfanyl)acetamide AldrichCPR C18H17ClN2O4S
    • CDS020529 (R)-(+)-[(5,6),(5′,6′)-Bis(ethylenedioxy)biphenyl-2,2′-diyl](diphenylphosphine) AldrichCPR C40H32O4P2