Coumarins

Coumarins are a group of plant-derived polyphenolic compounds. They belong to the benzopyrones family and possess a wide range of pharmaceutical applications including cytoprotective and modulatory functions, which may be translated into therapeutic potential for multiple diseases. Several natural and synthetic coumarins and derivatives, such as coumarin glycosides, possess potent biological activities. Coumarin derivatives are found in antibiotic, antimitotic, immunomodulating, antiviral, anticancer, anti-inflammatory, anticoagulant, antifungal, antioxidant, and cytotoxic agents, as well as some biological assays.

Coumarins have additional industrial applications. The fluorescence of coumarins, such as 7-hydroxycoumarin, is widely used as a research tool in polymer science. Coumarins are used as laser dye-sensitized photoinitiators, for incorporation into polymer chains by co-polymerization, in the estimation of polymer solvent effects, for various structural characterizations, in the monitoring of the releasing properties of poly(methylmethacrylate) nanospheres and for polymeric fluorescent solar collectors.

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Takasago Ligands

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513083 4-Chloro-3-nitrocoumarin 96% C9H4ClNO4
732990 7-Bromo-4-hydroxycoumarin C9H5BrO3
579572 3-Chlorocoumarin 97% C9H5ClO2
417343 6-Chloro-4-hydroxycoumarin 97% C9H5ClO3
438626 4-Hydroxy-3-nitrocoumarin 98% C9H5NO5
642673 3-Hydroxycoumarin C9H6O3
H23805 4-Hydroxycoumarin 98% C9H6O3
642665 6-Hydroxycoumarin 96% C9H6O3
H24003 Umbelliferone 99% C9H6O3
411183 3-Aminocoumarin 97% C9H7NO2
CDS019990 6-Amino-chromen-2-one AldrichCPR C9H7NO2
CDS000898 6-Aminocoumarin hydrochloride AldrichCPR C9H8ClNO2
D104809 Dihydrocoumarin 99% C9H8O2
550361 6-Bromo-4-chloro-3-formylcoumarin 97% C10H4BrClO3
550353 4,6-Dichloro-3-formylcoumarin 97% C10H4Cl2O3
550337 4-Chloro-3-formylcoumarin 97% C10H5ClO3
579696 3-Cyanocoumarin 97% C10H5NO2
C85603 Coumarin-3-carboxylic acid 99% C10H6O4
640611 3-Chloro-7-hydroxy-4-methylcoumarin 97% C10H7ClO3
CDS007255 6-Chloro-7-hydroxy-4-methyl-2H-chromen-2-one AldrichCPR C10H7ClO3
640646   7-Hydroxy-4-methyl-8-nitrocoumarin 96% C10H7NO5
M36203 6-Methylcoumarin ≥99% C10H8O2
220329 7-Methylcoumarin ≥98% C10H8O2
417351 4-Hydroxy-6-methylcoumarin 98% C10H8O3
M1381 4-Methylumbelliferone ≥98% C10H8O3
220337 7-Methoxycoumarin ≥98% C10H8O3
543594 5,7-Dihydroxy-4-methylcoumarin 98% C10H8O4
630748 7,8-Dihydroxy-4-methylcoumarin 97% C10H8O4
550310 6-Bromo-3-cyano-4-methylcoumarin 97% C11H6BrNO2
543713 6-Fluoro-4-methylcoumarin-3-carbonitrile 97% C11H6FNO2
579920 3-(Bromoacetyl)coumarin 97% C11H7BrO3
538590 3-Acetyl-6-bromocoumarin 97% C11H7BrO3
550345 4-Chloro-3-formyl-6-methylcoumarin 97% C11H7ClO3
438618 3-Cyano-4-methylcoumarin 97% C11H7NO2
438596 3-Cyano-7-hydroxy-4-methylcoumarin 97% C11H7NO3
214671 3-Acetylcoumarin 96% C11H8O3
630756 8-Acetyl-7-hydroxycoumarin 97% C11H8O4
335665 7-Hydroxycoumarinyl-4-acetic acid 97% C11H8O5
235202 4-Bromomethyl-7-methoxycoumarin 97% C11H9BrO3
CDS003706 2-(7-Hydroxy-2-oxo-2H-chromen-4-yl)acetamide AldrichCPR C11H9NO4
544256 4-Ethoxycoumarin 97% C11H10O3
CDS009714 5-Hydroxy-4,7-dimethyl-2H-chromen-2-one AldrichCPR C11H10O3
116238 5,7-Dimethoxycoumarin 98% C11H10O4
254886 6,7-Dimethoxycoumarin 98% C11H10O4
CDS008891 7,8-dimethoxycoumarin AldrichCPR C11H10O4
CDS006945 7-hydroxy-4-methoxymethylcoumarin AldrichCPR C11H10O4
417327 4-Hydroxy-6,7-dimethylcoumarin 98% C11H12O4
550302 3-Cyano-4,6-dimethylcoumarin 97% C12H9NO2
CDS009937 7-ethylamino-4-trifluoromethylcoumarin AldrichCPR C12H10F3NO2
CBR01149 (7-Methyl-2-oxo-2H-chromen-4-yl)acetic acid AldrichCPR C12H10O4
390801 Ethyl 3-coumarincarboxylate 99% C12H10O4
298557 7-(Carboxymethoxy)-4-methylcoumarin 97% C12H10O5
235199 7-Methoxycoumarin-4-acetic acid 97% C12H10O5
301450 4-Bromomethyl-6,7-dimethoxycoumarin 96% C12H11BrO4
CDS004168 4-Ethyl-7-hydroxy-8-methyl-2H-chromen-2-one AldrichCPR C12H12O3
CDS004268 6-ethoxy-4-methylcoumarin AldrichCPR C12H12O3
CDS011665 6-Ethyl-7-hydroxy-4-methyl-2H-chromen-2-one AldrichCPR C12H12O3
293512 7-Hydroxy-3,4,8-trimethylcoumarin 97% C12H12O3
578339 5,7-Dihydroxy-4-propylcoumarin 98% C12H12O4
316407 6,7-Dimethoxy-4-methylcoumarin 97% C12H12O4
130184 7-Nitro-3,4-benzocoumarin 98% C13H7NO4
300233 6-Amino-3,4-benzocoumarin 99% C13H9NO2
CDS019350 7-Allyloxy-2-oxo-2H-chromene-4-carboxylic acid AldrichCPR C13H10O5
CDS005754 3-Allyl-7-hydroxy-4-methyl-2H-chromen-2-one AldrichCPR C13H12O3
CDS008908 6-Acetyl-7-hydroxy-4,8-dimethyl-2H-chromen-2-one AldrichCPR C13H12O4
CDS007378 6,7-dimethoxy-4-ethylcoumarin AldrichCPR C13H14O4
CDS010061 6-acetyl-7-hydroxy-3,4,8-trimethyl-chromen-2-one AldrichCPR C14H14O4
CDS009067 3-(7-Methoxy-4-methyl-2-oxo-2H-chromen-6-yl)propanoic acid AldrichCPR C14H14O5
CDS007419 (6,7-Dimethoxy-4-methyl-2-oxo-2H-chromen-3-yl)-acetic acid AldrichCPR C14H14O6
576468 7-Hydroxy-4-phenylcoumarin 97% C15H10O3
578320 5,7-Dihydroxy-4-phenylcoumarin C15H10O4
576441 7,8-Dihydroxy-4-phenylcoumarin C15H10O4
576425 4,5,7-Trihydroxy-3-phenylcoumarin 97% C15H10O5
576417 7-Hydroxy-3-methyl-4-phenylcoumarin 98% C16H12O3
578312 7-Hydroxy-4-methyl-3-phenylcoumarin 97% C16H12O3
576433 4-Hydroxy-7-methoxy-3-phenylcoumarin 97% C16H12O4
173584 7-Acetoxy-6-(2,3-dibromopropyl)-4,8-dimethylcoumarin 97% C16H16Br2O4
CDS007318 7,8-diallyloxy-4-methylcoumarin AldrichCPR C16H16O4
188611 3-[2-(Diethylamino)ethyl]-7-hydroxy-4-methylcoumarin hydrochloride C16H21NO3 · HCl
CDS009574 (2-Oxo-4-phenyl-2H-chromen-7-yloxy)-acetic acid AldrichCPR C17H12O5
189219 Coumachlor 98% C19H15ClO4
A4571 3-(α-Acetonylbenzyl)-4-hydroxycoumarin sodium salt ≥98% C19H15NaO4