Benzodioxanes

Benzodioxane derivatives, bicyclic heterocyclic systems consisting of a benzene ring fused to a heterocyclic dioxane ring, represent a series of synthetic and natural compounds of considerable medicinal importance. Compounds containing the dioxane or the 1,4-benzodioxane moiety exhibit various biological activities such as antihepatotoxic (hepatoprotective), α-adrenergic blocking agent activity, anti-inflammatory, antigrastic, spasmolytic, antipsychotic, anxiolytic, and D2 antagonist/5-HT1A partial agonist activity. The presence of a halogen allows these reagents to be used as substrates in various coupling reactions, including Suzuki-Miyaura cross-coupling reactions.

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CDS013917 5-bromo-2,2-difluoro-1,3-benzodioxole AldrichCPR C7H3BrF2O2
    • CDS003013 2,2-Difluoro-1,3-benzodioxole-4-carbaldehyde AldrichCPR C7H4F2O2
    • 739383 2,2-Difluoro-1,3-benzodioxole-4-carboxaldehyde 97% C7H4F2O2
    • CDS015940 1,3-benzodioxole-5-sulfonyl chloride AldrichCPR C7H5ClO4S
    • CDS003005 5-Iodo-1,3-benzodioxole AldrichCPR C7H5IO2
    • CBR00760 1,3-Benzodioxol-5-ylhydrazine hydrochloride AldrichCPR C7H9ClN2O2
    • 738913 6-Bromo-1,3-benzodioxole-5-carbonitrile 97% C8H4BrNO2
    • CDS011641 7-chloro-1,3-benzodioxole-5-carbaldehyde AldrichCPR C8H5ClO3
    • 538523 6-Bromo-1,4-benzodioxane 97% C8H7BrO2
    • CDS016454 (6-bromo-1,3-benzodioxol-5-yl)methanol AldrichCPR C8H7BrO3
    • CDS013599 6-iodo-2,3-dihydro-1,4-benzodioxine AldrichCPR C8H7IO2
    • CBR00939 2,3-Dihydro-1,4-benzodioxin-6-ylhydrazine hydrochloride AldrichCPR C8H11ClN2O2
    • CDS014400 6-fluoro-4H-1,3-benzodioxin-8-yl isocyanate AldrichCPR C9H6FNO3
    • CDS008060 7-bromo-2,3-dihydro-1,4-benzodioxine-6-carbaldehyde AldrichCPR C9H7BrO3
    • CDS006548 7-Bromo-2,3-dihydro-1,4-benzodioxine-6-carboxylic acid AldrichCPR C9H7BrO4
    • CDS013957 2,3-dihydro-1,4-benzodioxine-2-carbonyl chloride AldrichCPR C9H7ClO3
    • CDS016028 2,3-dihydro-1,4-benzodioxine-5-carbonyl chloride AldrichCPR C9H7ClO3
    • CDS013024 8-chloro-2,3-dihydro-1,4-benzodioxine-6-carbaldehyde AldrichCPR C9H7ClO3
    • CDS013002 8-chloro-2,3-dihydro-1,4-benzodioxine-6-carboxylic acid AldrichCPR C9H7ClO4
    • CDS017647 6-fluoro-4H-1,3-benzodioxine-8-carbaldehyde AldrichCPR C9H7FO3
    • CDS013659 6-fluoro-4H-1,3-benzodioxine-8-carboxylic acid AldrichCPR C9H7FO4
    • 632643 2-Bromomethyl-1,4-benzodioxane 97% C9H9BrO2
    • CDS019440 6-(Bromomethyl)-2,3-dihydrobenzo[b][1,4]dioxine AldrichCPR C9H9BrO2
    • CDS013098 (8-chloro-2,3-dihydro-1,4-benzodioxin-6-yl)methylamine AldrichCPR C9H10ClNO2
    • CDS017882 1-(6,7-dichloro-2,3-dihydro-1,4-benzodioxin-5-yl)-1-ethanone AldrichCPR C10H8Cl2O3
    • CDS010773 (7-bromo-2,3-dihydro-1,4-benzodioxin-6-yl)acetic acid AldrichCPR C10H9BrO4
    • 532584 6-Chloroacetyl-1,4-benzodioxane 97% C10H9ClO3
    • CDS017983 7-(Chloromethyl)-3,4-dihydro-2H-1,5-benzodioxepine AldrichCPR C10H11ClO2
    • CDS012625 2-(8-chloro-2,3-dihydro-1,4-benzodioxin-6-yl)ethanamine hydrochloride AldrichCPR C10H13Cl2NO2
    • CDS020423 2-(2,3-Dihydro-1,4-benzodioxin-6-yl)ethanamine hydrochloride AldrichCPR C10H14ClNO2
    • CDS016361 1-(1,3-benzodioxol-5-yl)-4,4,4-trifluorobutane-1,3-dione AldrichCPR C11H7F3O4
    • CDS005649 4-(7-Chloro-2,3-dihydro-1,4-benzodioxin-6-yl)-1,3-thiazol-2-amine AldrichCPR C11H9ClN2O2S
    • CDS020223 Methyl 3-amino-3-(1,3-benzodioxol-5-yl)propanoate hydrochloride AldrichCPR C11H14ClNO4
    • CDS017124 4,7-dimethoxy-5-(2-propanyl)-1,3-benzodioxole AldrichCPR C12H14O4
    • CDS009708 2-bromo-3′,4′-(ethylenedioxy)benzophenone AldrichCPR C15H11BrO3
    • CDS019105 N-(7-Chloro-2,3-dihydro-1,4-benzodioxin-6-yl)-4-fluorobenzamide AldrichCPR C15H11ClFNO3
    • CDS014990 (7-bromo-2,3-dihydro-1,4-benzodioxin-6-yl)(4-methylphenyl)methanone AldrichCPR C16H13BrO3
    • CDS020562 N-[4-(Acetylamino)-3-chlorophenyl]-2-(2,3-dihydro-1,4-benzodioxin-6-ylsulfanyl)acetamide AldrichCPR C18H17ClN2O4S