Imidazolines/Imidazolidines

Imidazolines and are important heterocycles found in many biologically active compounds. Imidazolines are biologically active pharmacophores and synthetic intermediates in medicinal chemistry. Imidazolines are also used as chiral catalysts, chiral auxiliaries, and ligands for asymmetric catalysis. Imidazolines exhibit a range of biological activities including antihyperglycemic, anti-inflammatory, antihypertensive, anticancer, and antihypercholesterolemic agents, as well as antiulcer, antiviral, antifungal, antibacterial, antitubercular, antiasthmatic, anti-diabetic and antiprotozoal activities.

Imidazolines, such as fatty acid imidazolines, have industrial applications as corrosion inhibitors. The presence of a halogen allows these reagents to be used as substrates in various coupling reactions, including Suzuki-Miyaura cross-coupling reactions.

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N-Heterocyclic Carbene (NHC) Ligands
N-Heterocyclic Carbene (NHC) Ligands

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232807 1,3-Dichloro-5,5-dimethylhydantoin available chlorine 68 % C5H6Cl2N2O2
711624 1,3-Diiodo-5,5-dimethylhydantoin ≥96% C5H6I2N2O2
561312 3-Chlorocarbonyl-1-methanesulfonyl-2-imidazolidinone 97% C5H7ClN2O4S
CDS015162 [1-(4-chloro-phenyl)-2,5-dioxo-imidazolidin-4-yl]-acetic acid AldrichCPR C11H9ClN2O4
CDS013072 6′-Fluoro-2′,3′-dihydro-2H,5H-spiro[imidazolidine-4,4′-thiochromene]-2,5-dione 1′,1′-dioxide AldrichCPR C11H9FN2O4S
CDS004862 {2-Chloro-4-[(E)-(2,5-dioxo-4-imidazolidinylidene)methyl]phenoxy}acetic acid AldrichCPR C12H9ClN2O5
CDS019434 (5E)-5-[(2-Chlorophenyl)methylidene]-3-phenyl-2-sulfanylideneimidazolidin-4-one AldrichCPR C16H11ClN2OS