Indazoles

Indazole moieties differ from indole only by the presence of an additional ring nitrogen, and thus exhibit excellent potential as bioisosteres of the indole ring system. Various indazoles display significant activity as antifungals, antiinflammatory agents, antiarrhythmic agents, analgesics, and nitric oxide synthase inhibitors. The presence of a halogen allows these reagents to be used as substrates in various coupling reactions, including Suzuki-Miyaura cross-coupling reactions.

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Indoles and Indole Isosteres

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ADE000066 6-Bromo-1H-pyrazolo[4,3-b]pyridin-3-amine AldrichCPR C6H5BrN4
CDS006583 5-Chloro-3-iodo-1H-indazole AldrichCPR C7H4ClIN2
717525 3-Bromoindazole 95% C7H5BrN2
776610 4-Bromo-1H-indazole 95% C7H5BrN2
702293 5-Bromo-1H-indazole 97% C7H5BrN2
702447 6-Bromo-1H-indazole 95% C7H5BrN2
717088 7-Bromo-1H-indazole 97% C7H5BrN2
335207 3-Chloroindazole 97% C7H5ClN2
729922 4-Chloro-1H-indazole 97% C7H5ClN2
CDS006354 4-Chloro-1H-indazole AldrichCPR C7H5ClN2
CDS006550 5-Chloro-1H-indazole AldrichCPR C7H5ClN2
CDS006195 6-Chloro-1H-indazole AldrichCPR C7H5ClN2
CDS005203 7-Chloro-1H-indazole AldrichCPR C7H5ClN2
CDS020243 4-Chloro-1,2-dihydro-3H-indazol-3-one AldrichCPR C7H5ClN2O
701025 5-Fluoro-1H-indazole 97% C7H5FN2
CDS006466 6-Fluoro-1H-indazole AldrichCPR C7H5FN2
729930 4-Iodo-1H-indazole 95% C7H5IN2
CDS015924 4-bromo-1H-indazol-3-amine AldrichCPR C7H6BrN3
CDS005554 5-Bromo-1H-indazol-3-amine AldrichCPR C7H6BrN3
CDS013533 6-Bromo-1H-indazol-3-amine AldrichCPR C7H6BrN3
CDS019462 3-Amino-5-chloro-1H-indazole AldrichCPR C7H6ClN3
CDS012558 4-Fluoro-1H-indazol-3-amine AldrichCPR C7H6FN3
CDS020515 5-Chloro-1H-indazole-3-carbonitrile AldrichCPR C8H4ClN3
708100 3-Bromo-1H-indazole-5-carboxaldehyde 95% C8H5BrN2O
764426 6-Bromo-1H-indazole-4-carboxaldehyde 97% C8H5BrN2O
708097 3-Bromo-1H-indazole-5-carboxylic acid 97% C8H5BrN2O2
CDS015984 5-bromo-1H-indazole-3-carboxylic acid AldrichCPR C8H5BrN2O2
764418 6-Bromo-1H-indazole-4-carboxylic acid 97% C8H5BrN2O2
708119 3-Chloro-1H-indazole-5-carboxaldehyde 95% C8H5ClN2O
CDS006556 5-Chloro-1H-indazole-3-carboxylic acid AldrichCPR C8H5ClN2O2
CDS010312 6-Fluoro-1H-indazole-3-carboxylic acid AldrichCPR C8H5FN2O2
CDS015243 5-(trifluoromethyl)-1H-indazol-3-amine AldrichCPR C8H6F3N3
CDS016724 6-(trifluoromethyl)-1H-indazol-3-amine AldrichCPR C8H6F3N3
717215 3-Bromo-1-methylindazole 97% C8H7BrN2
CDS020030 4-Bromo-1-methyl-1H-indazole AldrichCPR C8H7BrN2
CDS019745 4-Bromo-3-methyl-1H-indazole AldrichCPR C8H7BrN2
CDS019644 5-Bromo-4-methyl-1H-indazole AldrichCPR C8H7BrN2
774979 5-Bromo-6-methyl-1H-indazole 97% C8H7BrN2
700967 5-Bromo-7-methyl-1H-indazole 97% C8H7BrN2
CVT00005 (6-Bromo-1H-indazol-4-yl)methanol AldrichCPR C8H7BrN2O
CDS005818 3-Iodo-4-methyl-1H-indazole AldrichCPR C8H7IN2
764434 4-(Aminomethyl)-6-bromo-1H-indazole 97% C8H8BrN3
CVT00004 Methyl 6-bromo-3-chloro-1H-indazole-4-carboxylate AldrichCPR C9H6BrClN2O2
CVT00003 Methyl 6-bromo-3-iodo-1H-indazole-4-carboxylate AldrichCPR C9H6BrIN2O2
CVT00002 Methyl 6-bromo-3-nitro-1H-indazole-4-carboxylate AldrichCPR C9H6BrN3O4
775142 Methyl 5-bromo-1H-indazole-6-carboxylate 95% C9H7BrN2O2
CVT00001 Methyl 6-bromo-1H-indazole-4-carboxylate AldrichCPR C9H7BrN2O2
CDS005062 1-Acetyl-4-chloro-1H-indazole AldrichCPR C9H7ClN2O
CDS016025 1-methyl-1H-indazole-3-carbonyl chloride AldrichCPR C9H7ClN2O
CDS007689 (5-Fluoro-1H-indazol-3-yl)-acetic acid AldrichCPR C9H7FN2O2
CDS010083 2-(5-Chloro-1H-indazol-3-yl)-acetamide AldrichCPR C9H8ClN3O
CDS020523 4-Bromo-1,5-dimethyl-1H-indazole AldrichCPR C9H9BrN2
CDS020525 5-Bromo-1,6-dimethyl-1H-indazole AldrichCPR C9H9BrN2
CDS020524 6-Bromo-1,5-dimethyl-1H-indazole AldrichCPR C9H9BrN2
CDS017185 3-(chloromethyl)-1-methyl-1H-indazole AldrichCPR C9H9ClN2
CBR01383 4-Chloro-1-ethyl-1H-indazol-3-amine AldrichCPR C9H10ClN3
CDS014314 (3-trifluoromethyl-4,5,6,7-tetrahydro-indazol-1-yl)-acetic acid AldrichCPR C10H11F3N2O2
CBR01202 3-(4,5,6,7-Tetrahydro-2H-indazol-3-yl)propanoic acid hydrochloride AldrichCPR C10H15ClN2O2
ANV00139 3-Iodo-6-nitro-1-[[2-(trimethylsilyl)ethoxy]methyl]-1H-Indazole AldrichCPR C13H18IN3O3Si
CDS015467 1-(3-bromophenyl)-4,5,6,7-tetrahydro-1H-indazole-3-carboxylic acid AldrichCPR C14H13BrN2O2
CDS015440 1-(4-bromophenyl)-4,5,6,7-tetrahydro-1H-indazole-3-carboxylic acid AldrichCPR C14H13BrN2O2