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Morpholines/Thiomorpholines

Morpholines are six-membered heterocycles featuring both amine and ether functional groups. Substituted morpholine derivatives are the core of various natural products and biologically active compounds. This class of compounds has found important applications in pharmaceuticals and agriculture. Chiral morpholine derivatives have found numerous applications in asymmetric synthesis as chiral auxiliaries as well as chiral ligands. Morpholine derivatives from synthesis and natural products have exhibited activity as antidepressants, appetite suppressants, antitumor agents, antioxidants, antibiotics, selective α1-agonists in the treatment of dementia and other central nervous system (CNS) disorders characterized by symptoms of noradrenergic insufficiency, as well as potent long acting human neurokinin-1 (hNK-1) receptor antagonists. Morpholines have several industrial applications, such as corrosion inhibitors, optical bleaching agents, and in textile dying, and fruit preservation. The presence of a halogen allows these reagents to be used as substrates in various coupling reactions, including Suzuki-Miyaura cross-coupling reactions.

Product #

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Description

Molecular Formula

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CDS019109 2,2,6,6-Tetrafluoromorpholine AldrichCPR C4H5F4NO
730556 N-Iodomorpholine hydriodide 97% C4H9I2NO
CDS019871 1-Oxide thiomorpholine hydrochloride AldrichCPR C4H10ClNOS
CDS019709 4-Chloromethanesulfonyl-morpholine AldrichCPR C5H10ClNO3S
CDS001440 4-Morpholinylformamidine hydrobromide AldrichCPR C5H12BrN3O
CDS001609 Homomorpholine hydrochloride AldrichCPR C5H12ClNO
CDS019178 4-(Bromoacetyl)morpholine AldrichCPR C6H10BrNO2
C42203 4-(2-Chloroethyl)morpholine hydrochloride 99% C6H12ClNO · HCl
23051 4-(2-Chloroethyl)morpholine hydrochloride purum, ≥97.0% (AT) C6H12ClNO · HCl
CDS020100 2-(Hydroxymethyl)homomorpholine hydrochloride AldrichCPR C6H14ClNO2
CBR01836 1-(4-Methyl-2-morpholinyl)methanamine hydrochloride AldrichCPR C6H15ClN2O
CBR00925 1-[4-(Methylsulfonyl)-2-morpholinyl]methanamine hydrochloride AldrichCPR C6H15ClN2O3S
CDS004316 4-(4-Bromo-1,3-thiazol-2-yl)morpholine AldrichCPR C7H9BrN2OS
CDS005996 4-(5-bromothiazol-2-yl)morpholine AldrichCPR C7H9BrN2OS
CBR00946 2-Morpholin-4-ylpropanoic acid hydrochloride AldrichCPR C7H14ClNO3
CBR00660 2-Morpholin-4-ylpropanohydrazide dihydrochloride AldrichCPR C7H17Cl2N3O2
728446 4-(4-Chlorobutyl)morpholine hydrochloride 97.0-103.0% (T) C8H16ClNO · HCl
CBR00867 3-Isobutylmorpholine hydrochloride AldrichCPR C8H18ClNO
CBR00675 trans-4-(4-Morpholinyl)-3-pyrrolidinol dihydrochloride AldrichCPR C8H18Cl2N2O2
CDS014941 4-(5-bromo-2-furoyl)morpholine AldrichCPR C9H10BrNO3
ADE000245 4-(3-Iodo-pyridin-2-yl)-morpholine AldrichCPR C9H11IN2O
ADE001299 4-(5-Iodo-pyridin-2-yl)-morpholine AldrichCPR C9H11IN2O
ADE000685 5-Bromo-2-morpholinopyridin-3-amine AldrichCPR C9H12BrN3O
CBR00624 4-Piperidin-4-ylthiomorpholine dihydrochloride AldrichCPR C9H20Cl2N2S
CBR00637 (5-Morpholin-4-ylpentyl)amine dihydrochloride AldrichCPR C9H22Cl2N2O
CDS016002 6-(4-chlorophenyl)-3-morpholinone AldrichCPR C10H10ClNO2
CDS019248 2-(2,4-Dichloro-5-fluorophenyl)morpholine AldrichCPR C10H10Cl2FNO
CDS019251 2-(3-Chloro-4-fluorophenyl)morpholine AldrichCPR C10H11ClFNO
CDS001294 4-[(2-Chloropyridin-3-yl)carbonyl]morpholine AldrichCPR C10H11ClN2O2
CBR00221 4-[(6-Chloro-3-pyridinyl)carbonyl]morpholine AldrichCPR C10H11ClN2O2
CDS014518 6-morpholinonicotinoyl chloride AldrichCPR C10H11ClN2O2
CDS019252 2-(3,4-Dichlorophenyl)morpholine AldrichCPR C10H11Cl2NO
CDS019250 2-(3,4-Difluorophenyl)morpholine AldrichCPR C10H11F2NO
CDS003639 1-bromo-3-(4-morpholino)benzene AldrichCPR C10H12BrNO
591777 4-(4-Bromophenyl)morpholine 97% C10H12BrNO
CDS019803 2-(4-Chlorophenyl)morpholine AldrichCPR C10H12ClNO
CDS019494 3-(2-Chlorophenyl)thiomorpholine AldrichCPR C10H12ClNS
CDS009573 3-(3-chlorophenyl)thiomorpholine AldrichCPR C10H12ClNS
CDS020431 3-(4-Chlorophenyl)thiomorpholine AldrichCPR C10H12ClNS
CDS019202 2-(2-Fluorophenyl)morpholine AldrichCPR C10H12FNO
CDS019249 2-(3-Fluorophenyl)morpholine AldrichCPR C10H12FNO
CDS020371 2-(4-Fluorophenyl)morpholine AldrichCPR C10H12FNO
736406 4-(4-Iodophenyl)morpholine 97% C10H12INO
CDS010500 3-(4-fluorophenyl) morpholine hydrochloride AldrichCPR C10H13ClFNO
CDS020186 2-Chloro-5-(4-morpholinyl)aniline AldrichCPR C10H13ClN2O
CDS005707 3-chloro-2-morpholin-4-yl-phenylamine AldrichCPR C10H13ClN2O
CDS002267 3-Chloro-4-(4-morpholinyl)aniline AldrichCPR C10H13ClN2O
CDS018224 3-(2-chlorophenyl) morpholine hydrochloride AldrichCPR C10H13Cl2NO
CDS017953 3-(4-chlorophenyl)morpholine hydrochloride AldrichCPR C10H13Cl2NO
CDS019190 3-Phenylmorpholine hydrochloride AldrichCPR C10H14ClNO
CBR00388 4-(4-Chloro-6-ethylpyrimidin-2-yl)morpholine AldrichCPR C10H14ClN3O
CBR00614 4-(Piperidin-3-ylmethyl)morpholine dihydrochloride hydrate AldrichCPR C10H24Cl2N2O2
ANV00034 (4-Bromophenyl)(morpholino)methanone AldrichCPR C11H12BrNO2
CDS020491 4-Bromo-2-(N-morpholino)-benzaldehyde AldrichCPR C11H12BrNO2
CDS009955 2-chloro-4-morpholin-4-yl-benzaldehyde AldrichCPR C11H12ClNO2
CDS016817 2-chloro-4-morpholinobenzenecarboxylic acid AldrichCPR C11H12ClNO3
CDS020130 3-Chloro-4-morpholinobenzoic acid AldrichCPR C11H12ClNO3
CDS013525 2-fluoro-4-(N-morpholino)-benzaldehyde AldrichCPR C11H12FNO2
CDS020326 3-Fluoro-2-(N-morpholino)-benzaldehyde AldrichCPR C11H12FNO2
CDS020121 2-Fluoro-4-morpholinobenzoic acid AldrichCPR C11H12FNO3
CDS020122 3-Fluoro-4-morpholinobenzoic acid AldrichCPR C11H12FNO3
CDS019200 4-Morpholin-4-yl-3-trifluoromethyl-phenylamine AldrichCPR C11H13F3N2O
CDS001330 2-(4-Chlorophenyl)-2-methylmorpholine AldrichCPR C11H14ClNO
CBR00622 4-(1-Piperidin-4-ylethyl)morpholine dihydrochloride AldrichCPR C11H24Cl2N2O
CDS013899 6-bromo-4-(4-morpholinyl)quinazoline AldrichCPR C12H12BrN3O
CDS020535 2-(3,5-Dichlorophenyl) morpholine oxalate AldrichCPR C12H13Cl2NO5
CDS008120 1-bromo-2-(1-morpholinocarbonylmethyl)benzene AldrichCPR C12H14BrNO2
CDS014726 4-benzyl-2-morpholinecarbonyl chloride hydrochloride AldrichCPR C12H15Cl2NO2
CDS016187 4-[2-(2-bromophenoxy)ethyl]morpholine AldrichCPR C12H16BrNO2
CDS003373 4-Benzyl-2-(chloromethyl)morpholine AldrichCPR C12H16ClNO
CDS007212 2-(2-chlorophenyl)-2-morpholin-4-ylethylamine AldrichCPR C12H17ClN2O
CDS002673 2-(4-Chloro-phenyl)-2-morpholin-4-yl-ethylamine AldrichCPR C12H17ClN2O
CBR00740 [2-(Morpholin-4-ylmethyl)phenyl]methanol hydrochloride AldrichCPR C12H18ClNO2
CDS020542 2-[4-(Trifluoromethyl)phenyl]morpholine oxalate AldrichCPR C13H14F3NO5
CDS017805 5-chloro-7-(morpholin-4-ylmethyl)quinolin-8-ol AldrichCPR C14H15ClN2O2
ADE000259 4-(3-Trimethylsilanylethynyl-pyridin-2-yl)-morpholine AldrichCPR C14H20N2OSi
CDS019445 3-Fluoro-4-[(4-morpholin-4-yl)piperidin-1-yl]phenylamine AldrichCPR C15H22FN3O