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Pyrazines

Pyrazines (paradiazines) are heterocyclic six-membered aromatic compounds containing para nitrogen atoms. Pyrazine derivatives are known for antitumor, antibiotic, anticonvulsant, antituberculosis and diuretic activities, as well as kinase, enzymatic, and potent tubulin and FtsZ polymerization inhibition. Pyrazines are volatile compounds that are also of interest to the cosmetic, food, flavor, and fragrance industries. The presence of a halogen allows these reagents to be used as substrates in various coupling reactions, including Suzuki-Miyaura cross-coupling reactions.

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Description

Molecular Formula

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CDS006372 5,6-dichloro-(1,2,5)oxadiazolo(3,4-b)pyrazine AldrichCPR C4Cl2N4O
709670 3,5-Dibromo-2-hydroxypyrazine 97% C4H2Br2N2O
465208 2,3-Dichloropyrazine 95% C4H2Cl2N2
132497 2,6-Dichloropyrazine 98% C4H2Cl2N2
SYX00011 2,6-Diiodopyrazine AldrichCPR C4H2I2N2
709735 2-Bromo-5-hydroxypyrazine 95% C4H3BrN2O
494364 2-Amino-3,5-dibromopyrazine 97% C4H3Br2N3
132489 2-Chloropyrazine 97% C4H3ClN2
CBR01733 6-Chloro-2-pyrazinol AldrichCPR C4H3ClN2O
513164 Iodopyrazine 97% C4H3IN2
636320 2-Amino-5-bromopyrazine 97% C4H4BrN3
720364 2-Amino-3-chloropyrazine 97% C4H4ClN3
685763 2,3-Diamino-5-bromopyrazine 97% C4H5BrN4
632619 3-Chloro-6-hydrazinopyridazine 97% C4H5ClN4
CDS018642 2-pyrazinecarbonyl chloride AldrichCPR C5H3ClN2O
759899 6-Chloro-1,2,4-triazolo[4,3-a]pyrazine 95% C5H3ClN4
CDS020025 3-Amino-6-bromopyrazine-2-carboxylic acid AldrichCPR C5H4BrN3O2
CDS013631 2-Chloro-6-methylpyrazine AldrichCPR C5H5ClN2
ANV00028 2-Chloro-6-methylpyrazine AldrichCPR C5H5ClN2
759228 2-Iodo-6-methoxypyrazine 95% C5H5IN2O
732125 2-Amino-5-bromo-3-methoxypyrazine 95% C5H6BrN3O
696110 2-Amino-5-bromo-3-(methylamino)pyrazine 97% C5H7BrN4
685798 3-Bromoimidazo[1,2-a]pyrazine 96% C6H4BrN3
688584 Methyl 5-chloro-2-pyrazinecarboxylate ≥98.0% (HPLC) C6H5ClN2O2
221139 3-Amino-6-(chloromethyl)-2-pyrazinecarbonitrile 4-oxide 97% C6H5ClN4O
737232 2-Methyl-5-(trifluoromethyl)pyrazine 96% C6H5F3N2
C38400 3-Chloro-2,5-dimethylpyrazine 98% C6H7ClN2
596833 Methyl 3,5-diamino-6-chloropyrazine-2-carboxylate 98% C6H7ClN4O2
737224 2-Chloro-3-nitrobenzotrifluoride 97% C7H3ClF3NO2
CDS010085 8-bromo-pyrido[3,4-b]pyrazine AldrichCPR C7H4BrN3
CBR01041 1-Methyl-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine hydrochloride AldrichCPR C8H13ClN2
CDS014017 4-methyl-2-(2-pyrazinyl)-1,3-thiazole-5-carbonyl chloride AldrichCPR C9H6ClN3OS
CBR00757 1-Ethyl-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine hydrochloride AldrichCPR C9H15ClN2
CBR01444 1-(2-Pyrazinyl)-3-piperidinamine dihydrochloride AldrichCPR C9H16Cl2N4
CDS004394 1-(4-Fluorophenyl)-1H-pyrazole-4-carbaldehyde AldrichCPR C10H7FN2O
CDS009268 tert-Butyl 3-bromo-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-carboxylate AldrichCPR C10H15BrN4O2
CDS009768 4-Chloro-1-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine AldrichCPR C11H6ClFN4
CDS011616 2-(2-chloro-benzyl)-5-methyl-2,4-dihydro-pyrazol-3-one AldrichCPR C11H11ClN2O
CDS017330 2-[3-(chloromethyl)piperidino]-6-methylpyrazine AldrichCPR C11H16ClN3
CDS017875 4-Chloro-1-(4-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine AldrichCPR C12H9ClN4O
CDS016135 2-(4-bromophenyl)-4-(2-hydroxyethyl)-5-methyl-1,2-dihydro-3H-pyrazol-3-one AldrichCPR C12H13BrN2O2
CDS011728 1-(4-Chlorophenyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine AldrichCPR C13H13ClN2
CDS018451 1-(4-Fluorophenyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine AldrichCPR C13H13FN2
ADE001245 1-(7-bromo-4-methyl-3,4-dihydropyrido[2,3-b]pyrazin-1(2H)-yl)-2,2-dimethylpropan-1-one AldrichCPR C13H18BrN3O