Ureas

Although urea is commonly used in the denaturation and solubilization of proteins, urea is also a key component in several synthetic organic reactions. For example, urea has been applied as a derivatization reagent for aldehydes and ketones producing crystalline compounds with characteristic melting points. Urea is also employed in the methylation of carboxylic acids, phenols, thiols, β-diketones, amino acids and amines. Other uses include Rh2(esp)2 catalyzed oxidative C–H activation, amination, and oxidative cyclization, condensation with an aldehyde in the Biginelli reaction, and urea-derivatized side chains to serve as metal ligating moieties.

Learn More about Ureas
Rh2(esp)2 Catalyst
Biginelli Reaction
C – H Amination
Task-Specific Ionic Liquids

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Molecular Formula

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U0631 Urea BioXtra, pH 7.5-9.5 (20 °C, 5 M in H2O) CH4N2O
    • U5128 Urea ACS reagent, 99.0-100.5% CH4N2O
    • 84940 Semicarbazide hydrochloride purum p.a., ≥98.0% (AT) CH5N3O · HCl
    • S2201 Semicarbazide hydrochloride ≥99% CH5N3O · HCl
    • 160555 1-Cyanoisourea sodium salt 98% C2H2N3NaO
    • 15270 Biuret C2H5N3O2
    • B54207 Biuret 97% C2H5N3O2
    • M86804 N-Methylurea 97% C2H6N2O
    • M53701 o-Methylisourea bisulfate 99% C2H6N2O · H2SO4
    • 455598 O-Methylisourea hemisulfate salt 99% C2H6N2O · 0.5 H2SO4
    • 273457 N-Guanylurea sulfate salt hydrate 97% C2H6N4O · 0.5H2O4S · xH2O
    • CDS019843 1-Amino-3-methylurea AldrichCPR C2H7N3O
    • CDS000493 N-(2-Chloroethyl)urea AldrichCPR C3H7ClN2O
    • 261394 1,1-Dimethylurea 99% C3H8N2O
    • D6254 N,N′-Dimethylurea ~98% C3H8N2O
    • 15450 N,N′-Dimethylurea (sym.), ≥99% (from N) C3H8N2O
    • 40410 N,N′-Dimethylurea (sym.), ≥95.0% (HPLC), technical C3H8N2O
    • 03970 N-Ethylurea purum, ≥98.0% (N) C3H8N2O
    • E51007 N-Ethylurea 97% C3H8N2O
    • 554693 (2-Hydroxyethyl)urea 95% C3H8N2O2
    • D4879 N,N′-Bis(hydroxymethyl)urea ≥95% C3H8N2O3
    • CDS005374 (2-Amino-ethyl)-urea hydrochloride AldrichCPR C3H10ClN3O
    • 92468 N,N′-Trimethyleneurea ≥98.0% C4H8N2O
    • A36808 N-Allylurea 95% C4H8N2O
    • 259454 1,1-Diethylurea 97% C5H12N2O
    • D101087 1,3-Diethylurea 97% C5H12N2O
    • B103004 N-Butylurea 99% C5H12N2O
    • 19939 N-tert-Butylurea ≥97.0% C5H12N2O
    • 87849 Tetramethylurea ≥99.5% (GC) C5H12N2O
    • T24503 Tetramethylurea 99% C5H12N2O
    • CDS000567 N-(2-Bromo-3-methylbutanoyl)urea AldrichCPR C6H11BrN2O2
    • CDS010709 3-fluorophenylurea AldrichCPR C7H7FN2O
    • P36959 N-Phenylurea 97% C7H8N2O
    • 245909 1-Phenylsemicarbazide 99% C7H9N3O
    • 79150 4-Phenylsemicarbazide puriss., for the detection of aldehydes and ketones, ≥98.5% (N) C7H9N3O
    • P34808 4-Phenylsemicarbazide 97% C7H9N3O
    • 221600 4-Phenylsemicarbazide hydrochloride 99% C7H9N3O · HCl
    • CDS001428 3-(2-Hydroxyethyl)-6-methyluracil AldrichCPR C7H10N2O3
    • 217298 1,3-Diallylurea 98% C7H12N2O
    • 43567 N,N′-Dipropylurea purum, ≥97.0% (C) C7H16N2O
    • 417629 N,N′-Dipropylurea 97% C7H16N2O
    • 226106 1,3-Bis(trimethylsilyl)urea 95% C7H20N2OSi2
    • 15248 N,N′-Bis(trimethylsilyl)urea purum, ≥98.0% (N) C7H20N2OSi2
    • CDS010583 4-(trifluoromethoxy)phenylurea AldrichCPR C8H7F3N2O2
    • CDS000094 2-Formyl-N-phenylhydrazinecarboxamide AldrichCPR C8H9N3O2
    • B1278 Benzyloxyurea C8H10N2O2
    • CDS020277 2-Methyl-2-([(prop-2-en-1-yl)carbamoyl]amino)propanoic acid AldrichCPR C8H14N2O3
    • 66638 N,N′-Diisopropyl-O-methylisourea purum, ≥97.0% (GC) C8H18N2O
    • 226408 o-Methyl-N,N′-diisopropylisourea 97% C8H18N2O
    • CDS016519 N-[3-(trifluoromethyl)benzyl]urea AldrichCPR C9H9F3N2O
    • D2425 Diuron ≥98% C9H10Cl2N2O
    • 332992 3-(4-Chlorophenyl)-1,1-dimethylurea 99% C9H11ClN2O
    • CDS019802 4-(3,3-Dimethyl-ureido)-benzenesulfonyl chloride AldrichCPR C9H11ClN2O3S
    • CDS016000 N-(2-chloroethyl)-N′-[4-(methylthio)phenyl]urea AldrichCPR C10H13ClN2OS
    • CDS020259 2′-o-Methyluridine AldrichCPR C10H14N2O6
    • 427527 Methyl 2-[3-(2-chloroethyl)ureido]benzoate 98% C11H13ClN2O3
    • 713333 1-(2-Dimethylaminoethyl)-3-phenylurea 99% C11H17N3O
    • 105937 3,4,4′-Trichlorocarbanilide 99% C13H9Cl3N2O
    • 390151 1,3-Bis(4-nitrophenyl)urea 97% C13H10N4O5
    • 142158 1,3-Diphenylurea 98% C13H12N2O
    • D80800 N,N′-Dicyclohexylurea 98% C13H24N2O
    • 484377 1,3-Bis[(2,2-dimethyl-1,3-dioxolan-4-yl)methyl]urea C13H24N2O5
    • 372900 3-Methyl-1,1-diphenylurea 99% C14H14N2O
    • CDS016466 N-(3-chlorophenyl)-N′-(2-hydroxy-1-phenylethyl)urea AldrichCPR C15H15ClN2O2
    • CDS001478 1-Benzyl-5-phenylbarbituric acid AldrichCPR C17H14N2O3
    • 372889 1,3-Diethyl-1,3-diphenylurea 99% C17H20N2O
    • CDS000351 N-Octadecylurea AldrichCPR C19H40N2O
    • 328030 1,3-Dioctadecylurea 97% C37H76N2O