Quinuclidines

Quinuclidine, a bicyclic amine, has found numerous applications, most notably as a ligand employed in studies on the OsO4-catalyzed dihydroxylation of olefins. These nitrogen containing heterocycles have also been used to form onium salts for testing of PAC-antagonist activity. 3-Quinuclidinol is a synthon for the preparation of cholinergic receptor ligands and anesthetics as well as a catalyst for condensation of methyl vinyl ketone with aldehydes. The presence of a halogen allows these reagents to be used as substrates in various coupling reactions, including Suzuki-Miyaura cross-coupling reactions.

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125210 3-Chloroquinuclidine hydrochloride 98% C7H12ClN · HCl
CDS010974 N-(4-chlorobenzyl)quinuclidin-3-amine AldrichCPR C14H19ClN2