Triazoles

Triazoles exhibit biological activity, notably as antifungals, antimicrobials, and enzymatic inhibitors. The azide-alkyne Huisgen cycloaddition is a mild and selective reaction that gives 1,2,3-triazoles as products. The reaction has been widely used in bioorthogonal chemistry and in organic synthesis. Triazole rings are relatively stable functional groups, and triazole linkages can be used in a variety of applications, such as replacement of the phosphate backbone of DNA. The presence of a halogen allows these reagents to be used as substrates in various coupling reactions, including Suzuki-Miyaura cross-coupling reactions.

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Hydroazidation Catalyst
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N-Acylbenzotriazoles

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CBR01726 5-Bromo-3-chloro-1H-1,2,4-triazole AldrichCPR C2HBrClN3
CDS019801 4H-1,2,4-Triazole-3-sulfonyl chloride AldrichCPR C2H2ClN3O2S
CBR00318 3-Bromo-5-(trifluoromethyl)-1H-1,2,4-triazole AldrichCPR C3HBrF3N3
CBR01399 3-Chloro-5-(trifluoromethyl)-1H-1,2,4-triazole AldrichCPR C3HClF3N3
CDS002200 5-Chloro-1H-1,2,3-triazole-4-carbonitrile AldrichCPR C3HClN4
CBR00168 3-(Trifluoromethyl)-1H-1,2,4-triazole AldrichCPR C3H2F3N3
CBR01814 3-Bromo-1-methyl-1H-1,2,4-triazole AldrichCPR C3H4BrN3
CBR01745 5-Bromo-1-methyl-1H-1,2,4-triazole AldrichCPR C3H4BrN3
CBR01778 3-Bromo-5-methoxy-1H-1,2,4-triazole AldrichCPR C3H4BrN3O
CBR01692 3-Chloro-1-methyl-1H-1,2,4-triazol-5-amine hydrochloride AldrichCPR C3H6Cl2N4
CBR00751 1-Methyl-1H-1,2,4-triazol-3-amine hydrochloride AldrichCPR C3H7ClN4
CBR01567 5-(Aminomethyl)-1H-1,2,4-triazol-3-amine dihydrochloride AldrichCPR C3H9Cl2N5
CBR01809 3-Bromo-1-methyl-1H-1,2,4-triazole-5-carbonitrile AldrichCPR C4H3BrN4
CBR01587 3-Bromo-N-methyl-1H-1,2,4-triazole-5-carboxamide AldrichCPR C4H5BrN4O
CBR01775 5-Bromo-1-ethyl-1H-1,2,4-triazole AldrichCPR C4H6BrN3
CBR01617 3-Bromo-5-methoxy-1-methyl-1H-1,2,4-triazole AldrichCPR C4H6BrN3O
CBR01576 5-Bromo-3-(methoxymethyl)-1H-1,2,4-triazole AldrichCPR C4H6BrN3O
CBR01765 3-Chloro-5-methoxy-1-methyl-1H-1,2,4-triazole AldrichCPR C4H6ClN3O
CDS020231 Methyl 5-amino-1H-1,2,4-triazole-3-carboxylate hydrochloride AldrichCPR C4H7ClN4O2
CBR00782 1-Ethyl-1H-1,2,4-triazol-5-amine hydrochloride AldrichCPR C4H9ClN4
CBR01009 2-(1H-1,2,3-Triazol-5-ylthio)ethanamine hydrochloride AldrichCPR C4H9ClN4S
CBR00641 2-(1H-1,2,4-Triazol-5-ylthio)ethanamine dihydrochloride AldrichCPR C4H10Cl2N4S
CBR01590 Methyl (3-chloro-1H-1,2,4-triazol-1-yl)acetate AldrichCPR C5H6ClN3O2
CBR01651 5-Bromo-1-isopropyl-1H-1,2,4-triazole AldrichCPR C5H8BrN3
CBR01816 5-Bromo-1-propyl-1H-1,2,4-triazole AldrichCPR C5H8BrN3
CBR01476 3-Chloro-1-ethyl-5-methoxy-1H-1,2,4-triazole AldrichCPR C5H8ClN3O
CDS019461 5,6,7,8-Tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride AldrichCPR C5H9ClN4
CBR01697 2-Isopropyl-2H-1,2,3-triazol-4-amine hydrochloride AldrichCPR C5H11ClN4
CBR00974 (1S)-1-(5-Methyl-4H-1,2,4-triazol-3-yl)ethanamine dihydrochloride AldrichCPR C5H12Cl2N4
CBR01570 2-(1-Methyl-1H-1,2,4-triazol-5-yl)ethanamine dihydrochloride AldrichCPR C5H12Cl2N4
CBR01711 3-(1H-1,2,3-Triazol-1-yl)-1-propanamine dihydrochloride AldrichCPR C5H12Cl2N4
CBR00626 3-(1H-1,2,4-Triazol-1-yl)propan-1-amine dihydrochloride AldrichCPR C5H12Cl2N4
CBR00987 2-[(3-Methyl-1H-1,2,4-triazol-5-yl)thio]ethanamine dihydrochloride hydrate AldrichCPR C5H14Cl2N4OS
CDS007659 5-Bromo-1H-benzotriazole AldrichCPR C6H4BrN3
SYX00001 1-Chlorobenzotriazole AldrichCPR C6H4ClN3
CDS008439 5-Fluoro-1H-benzotriazole AldrichCPR C6H4FN3
CBR01413 5,6,7,8-Tetrahydro[1,2,4]triazolo[4,3-a]pyridine hydrochloride AldrichCPR C6H10ClN3
CBR00744 4-(1H-1,2,4-Triazol-1-yl)butanoic acid hydrochloride AldrichCPR C6H10ClN3O2
CBR00648 1-(4-Ethyl-4H-1,2,4-triazol-3-yl)-N-methylmethanamine dihydrochloride AldrichCPR C6H14Cl2N4
CBR00643 1-(4-Propyl-4H-1,2,4-triazol-3-yl)methanamine dihydrochloride AldrichCPR C6H14Cl2N4
CBR00644 1-[4-(2-Methoxyethyl)-4H-1,2,4-triazol-3-yl]methanamine dihydrochloride AldrichCPR C6H14Cl2N4O
CBR01131 2-(4-Ethyl-4H-1,2,4-triazol-3-yl)ethanamine dihydrochloride hydrate AldrichCPR C6H16Cl2N4O
CDS006549 5-(Trifluoromethyl)-1H-1,2,3-benzotriazole AldrichCPR C7H4F3N3
CDS001394 1-(6-Chloro-2-pyridinyl)-1H-1,2,4-triazol-3-ol AldrichCPR C7H5ClN4O
CBR01520 ([1,2,4]Triazolo[4,3-a]pyridin-3-ylmethyl)amine dihydrochloride AldrichCPR C7H10Cl2N4
CBR01533 2-Methyl-1-(1-methyl-1H-1,2,4-triazol-5-yl)-1-propanamine hydrochloride AldrichCPR C7H15ClN4
CBR01029 2-[4-(2-Methoxyethyl)-4H-1,2,4-triazol-3-yl]ethanamine hydrochloride AldrichCPR C7H15ClN4O
CBR01215 1-(4-Isopropyl-4H-1,2,4-triazol-3-yl)-N-methylmethanamine dihydrochloride AldrichCPR C7H16Cl2N4
CBR00651 1-(4-Isopropyl-4H-1,2,4-triazol-3-yl)ethanamine dihydrochloride AldrichCPR C7H16Cl2N4
CBR00650 1-(4-Propyl-4H-1,2,4-triazol-3-yl)ethanamine dihydrochloride AldrichCPR C7H16Cl2N4
CBR00649 N-Methyl-1-(4-propyl-4H-1,2,4-triazol-3-yl)methanamine dihydrochloride AldrichCPR C7H16Cl2N4
CBR00652 1-[4-(2-Methoxyethyl)-4H-1,2,4-triazol-3-yl]-N-methylmethanamine dihydrochloride AldrichCPR C7H16Cl2N4O
CBR00653 1-[4-(2-Methoxyethyl)-4H-1,2,4-triazol-3-yl]ethanamine dihydrochloride AldrichCPR C7H16Cl2N4O
CBR01217 1-[4-(3-Methoxypropyl)-4H-1,2,4-triazol-3-yl]methanamine dihydrochloride AldrichCPR C7H16Cl2N4O
712566 4-Bromo-5-phenyl-1H-1,2,3-triazole ≥97.0% C8H6BrN3
CDS012878 3-chloromethyl-3H-benzo[d][1,2,3]triazin-4-one AldrichCPR C8H6ClN3O
573760 5-(4-Chlorophenyl)-2,4-dihydro-[1,2,4]-triazole-3-thione 97% C8H6ClN3S
CDS018777 1-(4-fluorophenyl)-1H-1,2,4-triazol-3-ol AldrichCPR C8H6FN3O
CDS013079 5-(3-bromophenyl)-4H-1,2,4-triazol-3-amine AldrichCPR C8H7BrN4
CDS013797 5-(4-bromophenyl)-4H-1,2,4-triazol-3-amine AldrichCPR C8H7BrN4
CBR00446 5-Chloro-2-(1H-1,2,4-triazol-1-yl)aniline AldrichCPR C8H7ClN4
CDS020581 3-(4-Fluorophenyl)-1H-1,2,4-triazol-5-amine AldrichCPR C8H7FN4
CDS006206 5-(2-Fluorophenyl)-4H-1,2,4-triazol-3-amine AldrichCPR C8H7FN4
CDS005583 5-(4-Fluorophenyl)-4H-1,2,4-triazol-3-amine AldrichCPR C8H7FN4
CBR01078 1-[2-(1H-1,2,4-Triazol-1-yl)ethyl]piperazine trihydrochloride hydrate AldrichCPR C8H20Cl3N5O
CDS012890 4-(4-Bromophenyl)-1H-1,2,3-triazole-5-carbonitrile AldrichCPR C9H5BrN4
CDS019735 6-Chloro-[1,2,4]triazolo[3,4-a]phthalazine AldrichCPR C9H5ClN4
CDS017777 1-(4-chlorophenyl)-1H-1,2,3-triazole-4-carbaldehyde AldrichCPR C9H6ClN3O
CDS016407 2-chloro-4-[1,2,4]triazol-4-yl-benzoic acid AldrichCPR C9H6ClN3O2
CDS016648 2-chloro-4-(1H-1,2,4-triazol-1-yl)benzenecarboxylic acid AldrichCPR C9H6ClN3O2
CDS018344 2-chloro-5-[1,2,4]triazol-4-yl-benzoic acid AldrichCPR C9H6ClN3O2
CDS020456 1-[4-(Bromomethyl)phenyl]-1H-1,2,4-triazole AldrichCPR C9H8BrN3
CDS016529 4-(chloromethyl)-1-phenyl-1H-1,2,3-triazole AldrichCPR C9H8ClN3
SYX00018 1-Benzotriazol-1-yl-3-chloropropan-2-one AldrichCPR C9H8ClN3O
CDS014789 1-(3,4-dichloro-benzyl)-1H-[1,2,4]triazol-3-ylamine AldrichCPR C9H8Cl2N4
CDS012580 3-[(2,6-Dichlorobenzyl)sulfanyl]-1H-1,2,4-triazol-5-amine AldrichCPR C9H8Cl2N4S
CDS014790 1-(2-chloro-benzyl)-1H-[1,2,4]triazol-3-ylamine AldrichCPR C9H9ClN4
CDS014788 1-(3-chloro-benzyl)-1H-[1,2,4]triazol-3-ylamine AldrichCPR C9H9ClN4
CDS016024 3-[(4-chlorobenzyl)sulfanyl]-1H-1,2,4-triazol-5-ylamine AldrichCPR C9H9ClN4S
CDS014722 1-(2-fluoro-benzyl)-1H-[1,2,4]triazol-3-ylamine AldrichCPR C9H9FN4
CDS014786 1-(3-fluoro-benzyl)-1H-[1,2,4]triazol-3-ylamine AldrichCPR C9H9FN4
CDS019307 5-(2-Methylphenyl)-4H-1,2,4-triazol-3-ylamine hydrochloride AldrichCPR C9H11ClN4
CBR01716 1-(5-Phenyl-4H-1,2,4-triazol-3-yl)methanamine dihydrochloride AldrichCPR C9H12Cl2N4
CBR01274 2-(3-Pyridin-3-yl-1H-1,2,4-triazol-5-yl)ethanamine dihydrochloride hydrate AldrichCPR C9H15Cl2N5O
CBR01522 5-Chloro-1H-1,2,4-triazole-3-carboxylic acid AldrichCPR C9H17ClN4O2
CBR01216 1-(4-Cyclohexyl-4H-1,2,4-triazol-3-yl)methanamine dihydrochloride AldrichCPR C9H18Cl2N4
CDS002168 1-(2-Chloro-6-fluorobenzyl)-1H-1,2,3-triazole-4-carboxylic acid AldrichCPR C10H7ClFN3O2
CDS017325 5-Methyl-2-phenyl-2H-1,2,3-triazole-4-carbonyl chloride AldrichCPR C10H8ClN3O
CDS012139 1-(4-Iodophenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid AldrichCPR C10H8IN3O2
CDS014494 4-(Bromomethyl)-5-methyl-2-phenyl-2H-1,2,3-triazole AldrichCPR C10H10BrN3
CDS017430 1-[2-(chloromethyl)benzyl]-1H-1,2,4-triazole AldrichCPR C10H10ClN3
CDS016569 [1-(3-fluorobenzyl)-1H-1,2,3-triazol-4-yl]methanol AldrichCPR C10H10FN3O
CDS020322 Methyl 2-(5-amino-1H-1,2,4-triazol-3-yl)benzoate hydrochloride AldrichCPR C10H11ClN4O2
CBR00793 1-[4-(1H-1,2,4-Triazol-1-yl)phenyl]ethanamine hydrochloride AldrichCPR C10H13ClN4
CBR00697 4-[(5-Methyl-4H-1,2,4-triazol-3-yl)methyl]aniline dihydrochloride AldrichCPR C10H14Cl2N4
CDS014922 1-[1-(3,5-dichlorophenyl)-5-methyl-1H-1,2,3-triazol-4-yl]ethan-1-one AldrichCPR C11H9Cl2N3O
CDS016010 1-(4-fluorobenzyl)-5-methyl-1,2,3-triazole-4-carboxylic acid AldrichCPR C11H10FN3O2
CDS010799 ([5-(2-Fluorophenyl)-4-methyl-4H-1,2,4-triazol-3-yl]thio)acetic acid AldrichCPR C11H10FN3O2S
CDS015910 1-(3-bromo-4-methoxyphenyl)-2-[(5-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]ethanone AldrichCPR C12H12BrN3O2S
CDS017367 1-[1-(4-fluoro-phenyl)-propyl]-1H-[1,2,3]triazole-4-carboxylic acid AldrichCPR C12H12FN3O2
CDS016394 7-(4-Fluorostyryl)[1,2,4]triazolo[1,5-a]pyrimidin-2-amine AldrichCPR C13H10FN5