PEG Azides

PEG polymers contain numerous inherent favorable biological characteristics including high water solubility and a lack of toxicity and immunogenicity. Thus, the chemical modification of biologically active compounds, such as peptides, antibody fragments, enzymes, or small molecules with polyethylene glycol chains, referred to as “PEGylation”, often leads to improved pharmacokinetics and biological function in many applications. PEG azides are ideal starting materials for the synthesis of PEG derivatives via azide-alkyne cycloaddition or Staudinger ligation.

Learn More about PEG Azides
Polyethylene Glycol Building Blocks for PEGylation
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76318 O-(2-Aminoethyl)-O′-(2-azidoethyl)heptaethylene glycol ≥90% (oligomer purity) C18H38N4O8
77787 O-(2-Aminoethyl)-O′-(2-azidoethyl)nonaethylene glycol ≥90% (oligomer purity) C22H46N4O10
76172 O-(2-Aminoethyl)-O′-(2-azidoethyl)pentaethylene glycol ≥90% (oligomer purity) C14H30N4O6
727423 2-[2-(2-Azidoethoxy)ethoxy]ethanol solution ~0.5 M in tert-butyl methyl ether C6H13N3O3
71613 O-(2-Azidoethyl)-O-[2-(diglycolyl-amino)ethyl]heptaethylene glycol ≥90% (oligomer purity) C22H42N4O12
689440 O-(2-Azidoethyl)heptaethylene glycol ≥95% (oligomer purity) C16H33N3O8
712590 O-(2-Azidoethyl)-O′-methyl-triethylene glycol ≥90% (NMR) C9H19N3O4
712604 O-(2-Azidoethyl)-O′-methyl-undecaethylene glycol ≥90% (NMR) C25H51N3O12
804665 Azido-PEG4-phenyloxadiazole methylsulfone ≥95% C17H23N5O7S
744751 14-Azido-3,6,9,12-tetraoxatetradecanoic acid solution ~0.5 M in tert-butyl methyl ether, ≥90% (HPLC) C10H19N3O6
17758 11-Azido-3,6,9-trioxaundecan-1-amine technical, ≥90% (GC) C8H18N4O3
765953 1,11-Diazido-3,6,9-trioxaundecane C8H16N6O3
689807 Methoxypolyethylene glycol azide PEG average Mn 2,000  
689475 Methoxypolyethylene glycol azide  
689696 Polyoxyethylene bis(azide) 2000  
689580 Polyoxyethylene bis(azide) 5000