Buchwald Ligands and Complexes

Aldrich Chemistry is your source for Commercial Buchwald Catalysts and Ligands.

Most competitive pricing on the market

We have repriced the Buchwald family of ligands and catalysts to be the most competitively priced portfolio on the market without sacrificing any of the high quality and product value you′ve come to expect from Aldrich. We are now offering products in the portfolio at reductions of up to 69% from our former prices.

IP Free at any scale

For over a decade, Aldrich Chemistry has provided superior Catalysts and Ligands to customers around the world. In collaboration with the Buchwald lab, we are pleased to offer the entire Buchwald portfolio of products royalty-free at any scale or step in the synthetic process. We′ve taken care of the IP so you don′t have to. Just buy and go!

Additionally, Aldrich manufacturing has expanded its existing capabilities to include commercial-scale to support demand. Visit process development quantities for a list of available products.

For additional information on our Commercial Buchwald product offering and Commercial license management, please contact us at catalysis@sial.com.


Buchwald Precatalyst Activation


Pd-precatalysts



Structural Features of Buchwald Ligands


Buchwald dialkylbiaryl ligands

Buchwald 4th Generation Palladacycles

Product #

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Description

Molecular Formula

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900608 APhos Pd G4 95% C30H43N2O3PPdS
900340 rac-BINAP Pd G4 C58H47NO3P2PdS
804355 BrettPhos Pd G4 C49H68NO5PPdS
900701 P(t-Bu)3 Pd G4 New C26H42NO3PPdS
900533 (t-Bu)PhCPhos Pd G4 95% C40H48N3O3PPdS
900349 cataCXium Pd G4 C38H54NO3PPdS
900471 CPhos Pd G4 95% C42H56N3O3PPdS
900284 CyJohnPhos Pd G4 New C38H46NO3PPdS
900702 DavePhos Pd G4 New C40H51N2O3PPdS
900454 DPPF Pd G4 95% C48H43FeNO3P2PdS
900276 MorDalPhos Pd G4 C44H57N2O4PPdS
900698 Neopentyl(tBu)2P Pd G4 ≥95% New C27H44NO3PPdS
900287 PCy3 Pd G4 C32H48NO3PPdS
804290 RuPhos Pd G4 C44H58NO5PPdS
804282 SPhos Pd G4 C40H50NO5PPdS
900700 (tBu)2PMe Pd G4 New C23H36NO3PPdS
900699 (tBu)2PPh Pd G4 ≥95% New C28H38NO3PPdS
900472 (R)-TolBINAP Pd G4 95% C62H55NO3P2PdS
900329 XantPhos Pd G4 C53H47NO4P2PdS
900455 N-XantPhos Pd G4 95% C50H42N2O4P2PdS
804274 XPhos Pd G4 95% C47H64NO3PPdS

Buchwald 3rd Generation Palladacycles

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Description

Molecular Formula

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776106 AdBrettPhos Pd G3 C56H74NO5PPdS
764183 APhos Pd G3 97% C29H41N2O3PPdS
761605 BrettPhos Pd G3 95% C48H66NO5PPdS
RNI00188 (t-Bu)2PhP Pd G3 C27H36NO3PPdS
RNI00185 (t-Bu)2PMe-Pd-G3 C22H34NO3PPdS
762229 tBuXPhos Pd G3 95% (dried basis) C42H58NO3PPdS
761435 cataCXium® A Pd G3 95% C37H52NO3PPdS
763004 CPhos Pd G3 95% C41H54N3O3PPdS
900621 CyJohnPhos Pd G3 95% C37H44NO3PPdS
RNI00192 CyJohnPhos Pd G3 AldrichCPR C37H44NO3PPdS
764175 P(Cy3) Pd G3 97% C31H46NO3PPdS
807850 DTBPF-Pd-G3 GT capsule C39H57FeNO3P2PdS
762830 JackiePhos Pd G3 95% C52H50F12NO5PPdS
747130 Josiphos SL-J009-1 Pd G3 C45H65FeNO3P2PdS
804851 Mesyl[(tri-t-butylphosphine)-2-(2-aminobiphenyl)]palladium(II) C25H40NO3PPdS
792357 MorDalphos Pd G3 C43H55N2O4PPdS
794201 Neopentyl(t-Bu)2P Pd G3 95% C26H42NO3PPdS
773905 RockPhos Pd G3 C44H62NO4PPdS
763403 RuPhos Pd G3 95% C43H56NO5PPdS
776246 SPhos Pd G3 97% C39H48NO5PPdS
745979 tBuBrettPhos Pd G3 96% C44H62NO5PPdS
762822 [(1,3,5,7-Tetramethyl-6-phenyl-2,4,6-trioxa-6-phosphaadamantane)-2-(2′-amino-1,1′-biphenyl)]palladium(II) methanesulfonate C29H34NO6PPdS
804835 P(o-tol)3 Pd G3 C34H34NO3PPdS
796530 TrixiePhos Pd G3 C41H44NO3PPdS
763039 XantPhos Pd G3 95% C52H45NO4P2PdS
794228 N-XantPhos Pd G3 95% C49H40N2O4P2PdS
763381 XPhos Pd G3 95% C46H62NO3PPdS

Buchwald 2nd Generation Palladacycles

Product #

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Description

Molecular Formula

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764299 APhos Pd G2 C28H38ClN2PPd
RNI00183 (t-Bu)2 MeP Pd G2 AldrichCPR C21H31ClNPPd
761311 cataCXium® A Pd G2 C36H49ClNPPd
763012 CPhos Pd G2 95% C40H51ClN3PPd
747807 CyJohnPhos Pd G2 C36H41ClNPPd
792349 MorDalphos Pd G2 C42H52ClN2OPPd
794198 Neopentyl-tBu2P Pd G2 C25H39ClNPPd
753246 RuPhos Pd G2 C42H53ClNO2PPd
753009 SPhos Pd G2 C38H45ClNO2PPd
763314 sSPhos Pd G2 95% C38H44ClNNaO5PPdS
763047 XantPhos-Pd-G2 C51H42ClNOP2Pd
741825 XPhos Pd G2 C45H59ClNPPd
805637 XPhos-Pd-G2 GT capsule C45H59ClNPPd

Buchwald 1st Generation Palladacycles

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Description

Molecular Formula

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718750 BrettPhos Pd G1, Methyl t-Butyl Ether Adduct may contain up to 1 mole equivalent of MTBE, 97% C43H63ClNO2PPd
741868   Buchwald Palladacycle Precatalyst Kit  
708739 tBuXPhos Pd G1 C37H55ClNPPd
707589 RuPhos Pd G1 Methyl -Butyl Ether Adduct 95% C38H53ClNO2PPd · CH3OC4H9
704946 SPhos Pd G1, Methyl t-Butyl Ether Adduct C39H57ClNO3PPd
704954 XPhos Pd G1 C41H59ClNPPd

Related Palladacycles

Product #

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Description

Molecular Formula

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677264 APhos 95% C16H28NP
481084 rac-BINAP 97% C44H32P2
756482 P(t-Bu)3 Pd G2 C24H37ClNPPd
671479 cataCXium® A 95% C24H39P
759171 CPhos 98% C28H41N2P
642629 Di-tert-butylmethylphosphine 97% C9H21P
676187 Di-tert-butylneopentylphosphine 95% C13H29P
682411 Di-tert-butylphenylphosphine 95% C14H23P
88733 (R)-1-[(SP)-2-(Dicyclohexylphosphino)ferrocenyl]ethyldi-tert-butylphosphine ≥97% C32H52FeP2
177261 DPPF 97% Green Alternative C34H28FeP2
695149 DTBPF C26H44FeP2
731013 JackiePhos 95% C39H37F12O2P
RNI00044 Josiphos SL-J009-2-G3-palladacycle AldrichCPR C45H64FeNO3P2PdS
751618 MorDalphos 97% C30H42NOP
756741 PCy3 Pd G2 95% C30H43ClNPPd
791016 RockPhos 97% C31H49OP
804282 SPhos Pd G4 C40H50NO5PPdS
695459 1,3,5,7-Tetramethyl-6-phenyl-2,4,8-trioxa-6-phosphaadamantane 97% C16H21O3P
693049 (R)-Tol-BINAP C48H40P2
807869 P(o-Tolyl)3-Pd-G2 GT capsule C33H31ClNPPd
570958 Tri-tert-butylphosphine 98% C12H27P
261971 Tricyclohexylphosphine C18H33P
710342 TrixiePhos 97% C28H31P
526460 Xantphos 97% C39H32OP2
666564 N-XantPhos 97% C36H27NOP2

KitAlysis

Product #

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Description

Molecular Formula

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Z742064 KitAlysis Benchtop Inertion Box  
KITALYSIS-CN KitAlysis High-Throughput Buchwald-Hartwig Amination Reaction Screening Kit-Pack of 4  
KITALYSIS-RCM KitAlysis High-Throughput Medium (5, 6, 7) Ring Closing Metathesis Reaction Screening Kit - Pack of 2  
KITALYSIS-24PD KitAlysis High-Throughput 24 Pd Precatalyst Reaction Screening Kit-Pack of 2 New  
KITALYSIS-SM KitAlysis High-Throughput Suzuki-Miyaura Cross-Coupling Reaction Screening Kit - Pack of 4  
Z742108 KitAlysis 24-well Reaction Block and Inertion Box Combination Starter Set  
Z742107 KitAlysis 24-well Reaction Block and Screwdriver Set  

Buchwald Ligands

Product #

Image

Description

Molecular Formula

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ALD01834 3-Acetylamino-2-hydroxy-5-(trifluoromethyl)pyridine 95% C8H7F3N2O2
768154 AdBrettPhos 95% C43H61O2P
799718 AlPhos C52H67F4OP
767689 (2-Biphenyl)di-1-adamantylphosphine 97% C32H39P
900268 Bis(3,5-bis(trifluoromethyl)phenyl)(2′,6′-bis(isopropoxy)-3,6-dimethoxybiphenyl-2-yl)phosphine ≥95% C36H31F12O4P
718742 BrettPhos 96% C35H53O2P
659932 Buchwald Ligands Kit I  
687243 Buchwald Ligands Kit II  
698903 Buchwald Ligands Kit III  
695874 t-BuDavePhos 97% C22H32NP
638080 tBuXPhos 97% C29H45P
638099 CyJohnPhos 97% C24H31P
638021 DavePhos 97% C26H36NP
707430 2′-Dicyclohexylphosphino-2,4,6-trimethoxybiphenyl 97% C27H37O3P
638439 JohnPhos 97% C20H27P
792470 Me3(OMe)tBuXPhos 96% (HPLC) C33H53OP
695262 MePhos 97% C25H33P
675938 Me4tButylXphos 96% C33H53P
694088 Palladium(II) acetate-S-Phos(Pd:P 1:2), ChemDose tablets Loading 1μmol Pd(OAc)2 per magnesium aluminometasilicate tablet  
695882 PhDave-Phos 97% C26H24NP
638072 SPhos 97% C26H35O2P
638064 XPhos 97% Green Alternative C33H49P
685585 S-Phos, ChemDose tablets Loading: 2μmol per tablet C26H35O2P
685151 X-Phos, ChemDose tablets Loading: 2μmol per tablet C33H49P
663131 RuPhos 95% C30H43O2P
677280 sSPhos C26H34NaO5PS · xH2O
730998 tBuBrettPhos 97% C31H49O2P
695211 tBuMePhos 97% C21H29P
694053 Tris[dibenzylideneacetone]dipalladium(0)-S-Phos (Pd:P 1:2), ChemDose tablets Loading 0.5μmol Pd2(dba)3 per magnesium aluminometasilicate tablet (1μmol Pd per tablet)  
900331 VPhos 95% C33H49OP