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Drug Discovery

ADMET / DMPK

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Target ID/
Validation
Assay
Development
HT
Screening
Lead ID/
Optimization   
ADMET/
DMPK
 Preclinical/
Clinical

Sigma-Aldrich offers a wide range of resources, reagents and kits for metabolomic analysis including a large collection of amino acid metabolites and carbohydrate metabolites. We also offer a range of stable isotopically-labeled products that can provide accurate and non-radioactive in vivo studies of both nutrition and metabolism. Compounds labeled with stable isotopes like Carbon-13, Nitrogen-15, Deuterium and others can be identified and measured using techniques such as MRI and MRS. We provide highly purified stable isotope labeled metabolic precursors and compounds for the study of energy utilization in vivo, brain metabolism, protein and glucose metabolism, metabolomics, fatty acid metabolism and others.

  • Metabolomics
  • Stable Isotopes - ISOTEC
  • Hematology and Histology
  • Biochemical
  • Analytical/Chromatography
  • PreClinical Development


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