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Drug Discovery

Lead ID and Optimization

Click on each step of the Drug Discovery Workflow below to view associated products and services.

Target ID/
Validation
Assay
Development
HT
Screening
Lead ID/
Optimization   
ADMET/
DMPK
 Preclinical/
Clinical

Sigma-Aldrich provides the industry leader in the provision of the most extensive range of building blocks and reactive intermediates to aid the generation and optimization of lead compounds.  From complex bifunctional heterocycles to amines, alcohols, carboxylic acids and sulfonyl chlorides, these building blocks are useful in all phases of parallel, organic, and medicinal chemistry applications.  Our AldrichCPR service is also available to provide building blocks and reactive intermediates in ready-to-use format. This unique service is completely customizable allowing the customer to dictate the vial, amount of material and label data.


  • Analytical Chromatography
  • Lead Discovery and Optimization .
  • Chemical Synthesis
  • Quadrapure™ Metal Scavengers
  • AldrichCPR
  • Medicinal Chemistry
  • Peptides
  • Resin Explorer


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