Medicinal Chemistry

Quadrapure™ Metal Scavengers

Sigma-Aldrich now distributes QuadraPure™ metal scavengers worldwide. This application guide highlights the Macroporous and Microporous product lines.

 

QuadraPure™ Application Guide PDF(607 KB)

QuadraPure™ Metal Scavengers
Product Name Typical Experimental Capacity Metals Removed Effective in acid/base Product # 
Macroporous Scavengers  
QuadraPure™ TU 0.19 mmol/g
(based on Pd(OAc)2 in DCM)
Pd, Pt, Ru, Au, Ag, Cu(l), Hg, Pb, Cd, Ni Y/Y 655422
QuadraPure™ IDA 0.16 mmol/g
(based on Cu(acac)2 in DCM)
Fe(III), Al(III), Ga(III), In(III), Cu, Va, Pb, Ni, Zn, Cd, Fe(II), Be, Mn, Ca, Mg, Sr, Ba Ya/Y 657026
QuadraPure™ AMPA 0.17 mmol/g
(based on Ni(acac)2 in DCM)
Fe, Cu, Ni
Multivalent metal ions, particularly transition metals
Ya/Y 657611
apH <2 gives poorer scavenging
Microporous Scavengers  
The microporous resins demonstrate excellent scavenging properties, particularly for palladium, at different pH values, and in the presence of competing ligands and substrates. Metal loading capacity can be significantly higher for these microporous products.
Product Name Functional Group Loading Metals Removed Effective in acid/base Product # 
QuadraPure™ MPA 1.5 mmol/g Pd, Ru, Rh, Hg, Au, Ag, Cu(l), Hg, Pb, Ir, Pt, and Cd Y/Y 657662
QuadraPure™ AEA 1.3 mmol/g Pd+ many multivalent transition metals N/Y 657646
QuadraPure™ IMDAZ 1.5 mmol/g Pd, Os, Co + many multivalent transition metals N/Y 657654