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An alternative to Tetrahydrofuran and Dichloromethane
2-Methyltetrahydrofuran
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2-Methyltetrahydrofuran (2-MeTHF) is a versatile, more environmentally friendly solvent derived from a variety of agricultural byproducts.
Features & Benefits
- Quickly produces clean water phase splits (density of 0.86 g/mL at 25°C) without forming emulsions unlike THF or DCM
- More easily dried than THF or DCM
- Very stable even in highly acidic environments
- Non-reactive, aprotic polar solvent
- Forms an effective azeotrope with water
- Higher boiling point (78-80°C)
Lower solvent loss during reflux
Allows rapid formation of Grignard reactants
- Suitable replacement in most organometallic reactions where THF is used including Suzuki Coupling reactions
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Boiling Point |
Density g/mL
at 25°C |
Flash Point |
Viscosity
at 25°C |
Dielectric Constant
at 25°C |
| 2-Methyltetrahydrofuran |
78-80°C |
0.860 |
-12.0 |
0.600 |
6.97 |
| Tetrahydrofuran |
65-67°C |
0.889 |
-17.2 |
0.456 |
7.52 |
| Dichloromethane |
39.8-40°C |
1.325 |
none |
0.413 |
8.93 |
| Products |
| Product # |
Product Name |
Add to Cart |
| 414247 |
anhydrous, ≥99.0%, contains 250ppm BHT as stabilizer |
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| 673277 |
anhydrous, ≥99%, Inhibitor-free |
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| 155810 |
ReagentPlus®, ≥98.5%, contains 150-400ppm BHT as stabilizer |
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