Coenzyme A plays an important role in lipid biosynthesis, catabolic/oxidation processes and enzyme regulation. Coenzyme A is a key cofactor that aids in transferring acyl groups during enzymatic reactions. Researchers use isotopic tracer methods to study the kinetics of acyl coenzyme A activity. For example, a recent paper demonstrates a sensitive, accurate and precise method for the quantification of long chain acyl coenzyme A concentrations and enrichment using  ¹³C₁₆-palmitoyl coenzyme A as a tracer.⁽¹⁾ Radiolabeled acyl coenzyme A is also used in developing assays to quantify or measure enzymatic activity. An article describes an efficient purification method for coenzyme A using radiolabeled ¹⁴C-acyl coenzyme A.⁽²⁾ On the other hand, another paper illustrates the use of ¹³C-malonyl coenzyme A to measure the activity of malonyl coenzyme decarboxylase ⁽³⁾ in an effort to offer a safer, nonradioactive and sensitive method.

Until now, researchers had to rely on synthesizing their desired ¹³C-labeled acyl coenzyme A or use radiolabeled ¹⁴C-coenzyme A to perform their experiments. With increased interest in isotopically labeled coenzyme A tracers, we now offer a range of short-, medium- and long chain ¹³C-acyl coenzyme A products for your convenience. As a leader in the stable isotope industry, we are the first to provide this unique range of ¹³C-acyl coenzyme A products with the highest isotopic enrichment and purity to our customers. 

Acetyl-1, 2-¹³C₂ coenzyme A, lithium salt

99 atom % ¹³C

Malonyl coenzyme A, lithium salt

Malonyl-¹³C₃ coenzyme A, lithium salt, 95 % CP

99 atom % ¹³C

Octanoyl-2,4,6,8 -¹³C₄  coenzyme A, lithium salt, 95 % CP

99 atom % ¹³C

Oleoyl-¹³C₁₈ coenzyme A, lithium salt, 95 % CP

99 atom % ¹³C

Palmitoyl-1-¹³C coenzyme A, lithium salt, 95 % CP

99 atom % ¹³C

Palmitoyl-¹³C₁₆ coenzyme A, lithium salt, 95 % CP

99 atom % ¹³C

Stearoyl-¹³C₁₈ coenzyme A, lithium salt, 95 % CP

99 atom % ¹³C