Amino Acids and Derivatives

Stable Isotope Labeled Amino Acids and Derivatives for Biomolecular NMR

In structural genomics, the use of biomolecular NMR to study protein structure and function relies heavily on the use of stable isotope labeled proteins. In order to incorporate the stable isotope label into these proteins, researchers use labeled amino acids in a variety of methods that include peptide synthesis, cell-free protein synthesis, and microbial growth by media. Labeled amino acids provide the ability to incorporate 13C, 15N, and/or deuterium labels into the protein allowing the user a significant level of flexibility to create uniform, selective, or site-specific labeling patterns throughout the protein structure.

ISOTEC Stable Isotopes offers a full line of protected and unprotected amino acids labeled with 13C, 15N and/or deuterium. Our complete product line includes amino acid mixtures as well as all twenty amino acids with a variety of labeling patterns for all of your research needs. Contact Us for any questions, to request a quote or to place an order.

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722669 N-Acetyl-L-Val-13C5,15N-L-Leu-13C6 98 atom % 15N, 99 atom % 13C, 97% (CP)
489867 L-Alanine-1-13C 99 atom % 13C
485853 L-Alanine-2-13C,15N 98 atom % 15N, 99 atom % 13C
489883 L-Alanine-13C3,15N 98 atom % 15N, 98 atom % 13C
740055 L-Alanine-3-13C, 2-d 97 atom % D, 99 atom % 13C, 98% (CP)
710512 L-Alanine-3-13C,2,3,3-d3 97 atom % D, 98 atom % 13C, 98% (CP)
332127 L-Alanine-15N 98 atom % 15N
426199 Algal amino acid mixture-13C 98 atom % 13C
487910 Algal amino acid mixture-13C,15N 98 atom % 13C, 98 atom % 15N
608947 Algal amino acid mixture-15N 98 atom % 15N
607649 Algal amino acid mixture-13C,15N,d 98 atom % 13C, 97 atom % D, 98 atom % 15N
596906 Algal amino acid mixture-15N,d 97 atom % D, 98 atom % 15N
711187 5-Aminolevulinic acid-13C5, 15N hydrochloride 99 atom % 13C, 98 atom % 15N, 97% (CP)
600113 L-Arginine-15N4 hydrochloride [α]/D, 97% (CP)
608033 L-Arginine-13C6,15N4 hydrochloride 99 atom % 15N, 99 atom % 13C, 95% (CP)
736139 L-Arginine-α-15N hydrochloride 98 atom % 15N, 97% (CP)
485918 L-Asparagine-15N2 monohydrate 98 atom % 15N, 98% (CP)
636673 L-Asparagine-15N2,d8 98 atom % D, 98 atom % 15N, 98% (CP)
570745 L-Asparagine-15N2,d8 monodeuterate 98 atom % 15N, 98 atom % D
608157 L-Asparagine-13C4,15N2 monohydrate 98 atom % 15N, 98 atom % 13C, 95% (CP)
586285 L-Aspartic acid-1-13C,15N 99 atom % 13C, 98 atom % 15N
607703 L-Aspartic acid-2-13C,15N 98 atom % 15N, 99 atom % 13C
572519 L-Aspartic acid-15N,2,3,3-d3 98 atom % 15N, 98 atom % D
607835 L-Aspartic acid-13C4,15N 98 atom % 13C, 98 atom % 15N, 95% (CP)
332135 L-Aspartic acid-15N 98 atom % 15N
486760 Boc-Ala-OH-1-13C 99 atom % 13C
489913 Boc-Ala-OH-15N 98 atom % 15N
605077 Boc-Ala-OH-2-13C 99 atom % 13C
603449 Boc-Ala-OH-2-13C,15N 99 atom % 13C, 98 atom % 15N
492884 Boc-Ala-OH-12C3 99.9 atom % 12C
586749 Boc-Ala-OH-13C3 99 atom % 13C
492892 Boc-Ala-OH-3-13C 99 atom % 13C
485837 Boc-Ala-OH-13C3,15N 98 atom % 15N, 99 atom % 13C
605050 Boc-D-Ala-OH-3-13C 99 atom % 13C
486787 Boc-Ala-OH-3,3,3-d3 99 atom % D
579785 Boc-Asn-OH-(α-amine-15N) 98 atom % 15N
588792 Boc-Asp-OH-15N 98 atom % 15N
586188 Boc-Asp-OH-3-13C 99 atom % 13C
586404 Boc-Asp-OH-4-13C 99 atom % 13C
587702 Boc-Gln-OH-15N2 98 atom % 15N
588407 Boc-Glu-OBzl-13C5,15N 98 atom % 13C, 98 atom % 15N, 97% (CP)
587680 Boc-Glu-OH-1-13C 99 atom % 13C
587699 Boc-Glu-OH-15N 98 atom % 15N
486698 Boc-Gly-OH-1-13C 99 atom % 13C
587729 Boc-Gly-OH-1-13C,15N 99 atom % 13C, 98 atom % 15N
486701 Boc-Gly-OH-15N 98 atom % 15N, 99% (CP)
604992 Boc-Gly-OH-13C2 99 atom % 13C
485780 Boc-Gly-OH-2-13C 99 atom % 13C
587737 Boc-Gly-OH-13C2,15N 99 atom % 13C, 98 atom % 15N
489557 Boc-Gly-OH-2-13C,15N 98 atom % 15N, 99 atom % 13C
587710 Boc-Gly-OH-2,2-d2 98 atom % D
492930 Boc-Leu-OH-15N monohydrate 98 atom % 15N
615900 Boc-Leu-OH-5,5,5-d3 monohydrate 99 atom % D
609161 Boc-Lys(Z)-OH-α-15N 98 atom % 15N
589845 Boc-Met-OH-1-13C 99 atom % 13C
589853 Boc-Met-OH-(methyl-13C) 99 atom % 13C
486833 Boc-Phe-OH-15N 98 atom % 15N
605204 Boc-Phe-OH-2-13C 99 atom % 13C
676993 Boc-Pro-OH-15N 99 atom % 15N, 97% (CP)
737348 Boc-Pro-OH-13C5 98 atom % 13C, 97% (CP)
672866 Boc-Thr(Bzl)-OH-13C4,15N 98 atom % 15N, 99 atom % 13C, 97% (CP)
591092 Boc-Tyr-OH-15N 98 atom % 15N
604976 Boc-Val-OH-1-13C 99 atom % 13C
486019 Boc-Val-OH-15N 98 atom % 15N
616222 Boc-Val-OH-d8 98 atom % D
658057 L-Cysteine-13C3,15N 98 atom % 15N, 98 atom % 13C, 95% (CP)
609129 L-Cysteine-15N 98 atom % 15N, 95% (CP)
724041 NG,NG-Dimethyl-d6-L-arginine dihydrochloride 98 atom % D, 95% (CP)
486752 Fmoc-Ala-OH-1-13C 99 atom % 13C
489905 Fmoc-Ala-OH-15N 98 atom % 15N
605158 Fmoc-Ala-OH-2-13C 99 atom % 13C
605131 Fmoc-Ala-OH-13C3 99 atom % 13C, 99% (CP)
489956 Fmoc-Ala-OH-3-13C 99 atom % 13C
667064 Fmoc-Ala-OH, 13C3,15N 99 atom % 13C, 98 atom % 15N
485888 Fmoc-Ala-OH-3,3,3-d3 99 atom % D
653659 Fmoc-Arg(Pbf)-OH-13C6,15N4 98 atom % 15N, 98 atom % 13C, 97% (CP)
579890 Fmoc-Asn-OH-15N2 98 atom % 15N
687359 Fmoc-Asn-OH-13C4,15N2 99 atom % 13C, 98 atom % 15N, 95% (CP)
609137 Fmoc-Asn-OH-amine-15N 98 atom % 15N
668745 Fmoc-Asn(Trt)-OH-15N2 98 atom % 15N, 95% (CP)
668753 Fmoc-Asn(Trt)-OH-13C4, 15N2 98 atom % 15N, 99 atom % 13C, 95% (CP)
588628 Fmoc-Asp-OH-1-13C 99 atom % 13C
492906 Fmoc-Asp-OH-15N 98 atom % 15N, 99% (CP)
594695 Fmoc-Asp-OH-2-13C 99 atom % 13C
605263 Fmoc-Asp-OH-4-13C 98 atom % 13C, 99% (CP)
594075 Fmoc-Asp(OtBu)-OH-15N 98 atom % 15N
683639 Fmoc-Asp(OtBu)-OH-13C4,15N 98 atom % 13C, 98 atom % 15N, 97% (CP)
676608 Fmoc-Cys(Trt)-OH-15N 98 atom % 15N, 97% (CP)
703109 Fmoc-Gln-(Trt)-OH-15N2 98 atom % 15N, 97% (CP)
663956 Fmoc-Gln-(Trt)-OH-13C5,15N2 98 atom % 13C, 98 atom % 15N, 97% (CP)
685496 Fmoc-Gln(Trt)-OH-(amine-15N) 98 atom % 15N, 97% (CP)
490008 Fmoc-Glu-OH-15N 98 atom % 15N
729701 Fmoc-Glu-OH-5-13C 99 atom % 13C, 97% (CP)
609153 Fmoc-Glu(OtBu)-OH-15N 98 atom % 15N, 99% (CP)
666009 Fmoc-Glu(OtBu)-OH-13C5, 15N 98 atom % 15N, 99 atom % 13C, 95% (CP)
605182 Fmoc-Gly-OH-1-13C 99 atom % 13C
485756 Fmoc-Gly-OH-15N 98 atom % 15N
587745 Fmoc-Gly-OH-13C2 99 atom % 13C
489549 Fmoc-Gly-OH-2-13C 99 atom % 13C
489530 Fmoc-Gly-OH-13C2,15N 99 atom % 13C, 98 atom % 15N
603457 Fmoc-Gly-OH-2-13C,15N 99 atom % 13C, 98 atom % 15N
485772 Fmoc-Gly-OH-2,2-d2 98 atom % D
676969 Fmoc-His(Trt)-OH-15N3 98 atom % 15N, 97% (CP)
707295 Fmoc-His(Trt)-OH-13C6, 15N3 97 atom % 13C, 95 atom % 15N, 95% (CP)
578622 Fmoc-Ile-OH-15N 98 atom % 15N, 99% (CP)
597228 Fmoc-Ile-OH-13C6,15N 98 atom % 15N, 98 atom % 13C, 98% (CP)
485934 Fmoc-Leu-OH-1-13C 99 atom % 13C
485950 Fmoc-Leu-OH-15N 98 atom % 15N, 98% (CP)
615943 Fmoc-Leu-OH-5,5,5-d3 99 atom % D
577960 Fmoc-Lys(Boc)-OH-15N2 98 atom % 15N
653632 Fmoc-Lys(Boc)-OH-13C6,15N2 98 atom % 13C, 98 atom % 15N, 97% (CP)
605115 Fmoc-Met-OH-1-13C 99 atom % 13C, 99% (CP)
609196 Fmoc-Met-OH-15N 98 atom % 15N
653640 Fmoc-Met-OH-13C5,15N 98 atom % 13C, 98 atom % 15N, 97% (CP)
609072 Fmoc-Phe-OH-15N 98 atom % 15N, 99% (CP)
492965 Fmoc-Phe-OH-2-13C 99 atom % 13C
651443 Fmoc-Phe-OH-13C9,15N 98 atom % 13C, 98 atom % 15N, 98% (CP)
615994 Fmoc-Phe-OH-(phenyl-d5)-2,3,3-d3 98 atom % D
589519 Fmoc-Pro-OH-15N 98 atom % 15N
651451 Fmoc-Pro-OH-13C5,15N 98 atom % 13C, 98 atom % 15N
609145 Fmoc-Ser(tBu)-OH-15N 98 atom % 15N
658928 Fmoc-Ser(tBu)-OH-13C3,15N 99 atom % 13C, 98 atom % 15N
658162 Fmoc-Thr(tBu)-OH-15N 98 atom % 15N
694274 Fmoc-Thr(tBu)-OH-13C4, 15N 99 atom % 13C, 98 atom % 15N, 97% (CP)
676977 Fmoc-Trp(Boc)-OH-15N2 97 atom % 15N, 97% (CP)
718696 Fmoc-Trp(Boc)-OH-13C11, 15N2 98 atom % 15N, 99 atom % 13C, 97% (CP)
658898 Fmoc-Tyr (t-Bu)-OH-13C9,15N 98 atom % 13C, 98 atom % 15N, 97% (CP)
653624 Fmoc-Tyr-OH-15N 98 atom % 15N, 97% (CP)
658901 Fmoc-Tyr(tBu)-OH-15N 98 atom % 15N, 97% (CP)
485993 Fmoc-Val-OH-1-13C 99 atom % 13C, 98% (CP)
486000 Fmoc-Val-OH-15N 98 atom % 15N
642886 Fmoc-Val-OH-13C5,15N 98 atom % 15N, 98 atom % 13C, 99% (CP)
616087 Fmoc-Val-OH-d8 98 atom % D
607851 L-Glutamic acid-13C5,15N 98 atom % 15N, 98 atom % 13C, 95% (CP)
644560 L-Glutamic acid-13C5,15N,d9 99 atom % 13C, 98 atom % 15N, 98 atom % D
643874 L-Glutamic acid-15N,d9 98 atom % D, 98 atom % 15N
332143 L-Glutamic acid-15N 98 atom % 15N
490032 L-Glutamine-15N2 98 atom % 15N
570737 L-Glutamine-15N2,d10 98 atom % 15N, 98 atom % D
607983 L-Glutamine-13C5,15N2 98 atom % 13C, 98 atom % 15N
635081 L-Glutamine-13C5,15N2,d10 98 atom % 13C, 96 atom % D, 98 atom % 15N, 95% (CP)
299294 Glycine-15N 98 atom % 15N
489522 Glycine-13C2,15N 98 atom % 15N, 99 atom % 13C
741078 Glycyl-glycine-d8 deuteriochloride 97 atom % D, 98% (CP)
574368 L-Histidine-15N3 95 atom % 15N
722871 L-Histidine-13C6 hydrochloride monohydrate 97 atom % 13C, 98% (CP)
608009 L-Histidine-13C6,15N3 95 atom % 15N, 97 atom % 13C
707848 L-Histidine-13C6,15N3 hydrochloride monohydrate 98 atom % 13C, 98 atom % 15N, 98% (CP)
608092 L-Isoleucine-13C6,15N 98 atom % 13C, 98 atom % 15N, 95% (CP)
609013 L-Isoleucine-15N 98 atom % 15N, 98% (CP)
490067 L-Leucine-1-13C,15N 98 atom % 15N, 99 atom % 13C
607657 L-Leucine-2-13C,15N 98 atom % 15N, 99 atom % 13C
608173 L-Leucine-3-13C,15N 98 atom % 15N, 99 atom % 13C
608068 L-Leucine-13C6,15N 98 atom % 13C, 98 atom % 15N, 95% (CP)
607940 L-Leucine-13C6,d10 98 atom % D, 99 atom % 13C
340960 L-Leucine-15N 98 atom % 15N
609021 L-Lysine-15N2 hydrochloride 98 atom % 15N, 98% (CP)
608041 L-Lysine-13C6,15N2 hydrochloride 99 atom % 13C, 99 atom % 15N, 95% (CP)
608106 L-Methionine-13C5,15N 98 atom % 13C, 98 atom % 15N, 95% (CP)
609242 L-Methionine-15N 98 atom % 15N, 98% (CP)
721271 L-Methionine-(methyl-13C,d2) 98 atom % 13C, 98 atom % D
736147 L-Ornithine-13C5 hydrochloride 99 atom % 13C, 98% (CP)
737607 Pentaglycine-3,6,9,12,15,15-d6, O-d 97 atom % D, 95% (CP)
608017 L-Phenylalanine-13C9,15N 98 atom % 13C, 98 atom % 15N, 95% (CP)
490105 L-Phenylalanine-15N 98 atom % 15N
608114 L-Proline-13C5,15N 98 atom % 13C, 98 atom % 15N, 95% (CP)
608998 L-Proline-15N 98 atom % 15N, 98% (CP)
485985 L-Serine-2-13C,15N 99 atom % 13C, 98 atom % 15N
608130 L-Serine-13C3,15N 98 atom % 15N, 98 atom % 13C, 95% (CP)
609005 L-Serine-15N 98 atom % 15N, 98% (CP)
720518 L-Threonine-1-13C S & P tested, 99 atom % 13C, 97% (CP)
607770 L-Threonine-13C4,15N 98 atom % 13C, 98 atom % 15N
609099 L-Threonine-15N 98 atom % 15N, 98% (CP)
574600 L-Tryptophan-15N2 95 atom % 15N, 95% (CP)
574597 L-Tryptophan-13C11,15N2 95 atom % 15N, 97 atom % 13C, 95% (CP)
607991 L-Tyrosine-13C9,15N 98 atom % 15N, 98 atom % 13C, 95% (CP)
332151 L-Tyrosine-15N 98 atom % 15N
758159 L-Valine-13C5 99 atom % 13C, 97% (CP)
600148 L-Valine-13C5,15N 98 atom % 15N, 98 atom % 13C, 95% (CP)
490172 L-Valine-15N 98 atom % 15N