Dispersive SPE Tubes

Supel™ QuE Z-Sep QuEChERS Tubes

Fat Removal in Difficult Matrices

Key Features and Benefits
  • Useful for pesticide residue analysis
  • Proprietary technology, significantly diminishes interference from fatty matrices and pigments
  • Employs “Quick Easy Cheap Effective Rugged Safe” QuEChERS methodology

Request Evaluation Sample

Technology Overview

Supel™QuE
Brochure
- Multi-Residue Pesticide
Analysis in Food
and Agricultural
Products Using the QuEChERS Method

 

 

 

Analysis
of Compounds in Fatty
Matrices


View QuEChERS video
Introduction to Supel QuE Z-Sep
Supel QuE Z-Sep sorbents enhance sample cleanup for complex matrices by effectively removing more fat and color from sample extracts than traditional phases for QuEChERS. By eliminating problematic matrix interferences, Z-Sep products provide more robust LC-MS and GC-MS methods. This proprietary technology can replace C18 and PSA phases in your current methods without additional method development.

Supel QuE Z-Sep/C18, a combination of Discovery® DSC-18 and Z-Sep particles, is recommended for samples containing <15% fat. Supel QuE Z-Sep+, C18 and Z-Sep dual bonded to silica, is recommended for cleanup of samples containing >15% fat. Supel QuE Z-Sep is recommended for the anlysis of hydrophobic analytes in fatty matrices.

Support Data
The removal of oleins by various sorbents was tested. The mixture included 1mL solution of mono-, di- and tri-oleins in 90% acetonitrile:10% water and 25 mg of the sorbent. The oleins remaining in solution were measured by HPLC-ELSD. The retention of oleins on different sorbents is shown in the graph below.
 


Retention of mono-, di- and triglycerides from 90% acetonitrile:10% water mix.

 

Ordering Information
View product catalog

 

Technical Articles & References
Webinars
Recent Webcast: Use of Novel Zirconia-Based Cleanup Sorbents for the Analysis of Contaminants in Fatty Food Samples; hosted by LCGC.
Webinar: Basic Principles of Solid Phase Microextraction (SPME) Method Development
Articles
Fast Extraction and Low Level Detection of Chloramphenicol in Shrimp
Extraction and Analysis of Neonicotinoid Pesticides from Flower Blossoms Using QuEChERS and LC-MS
Increase Removal of Fat and Pigment from Avocado Extracts Prior to GC-MS Analysis of Pesticide and Metabolite Residue (Reporter US Volume 31.2)
Improve Pigment Removal and Decrease Matrix Interferences for Pesticide Determination in Oranges Using Supel QuE Z-Sep/C18 QuEChERS Sorbent
Reduce Matrix Background and Improve Overall Analyte Recovery for the Analysis of Pesticides in Beef Kidney
References
Łukasz Rajski, Ana Lozano, Ana Uclés, Carmen Ferrer, and Amadeo R Fernández-Alba; Determination of pesticide residues in high oil vegetal commodities by using various multi-residue methods and clean-ups followed by liquid chromatography tandem mass spectrometry. Journal of Chromatography. A, 2013, 1304:109. (Abstract)
Sapozhnikova, Y.; Lehotay, S.J. Multi-class, multi-residue analysis of pesticides, polychlorinated biphenyls, polycyclic aromatic hydrocarbons, polybrominated diphenyl ethers and novel flame retardants in fish using fast, low-pressure gas chromatography–tandem mass spectrometry. Analytica Chimica Acta, 2013, 758, 80-92.
Geis-Asteggiante, L.; Lehotay, S.J.; Lightfield, A. R.; Dutko, T.; Ng, C.; Bluhm, L.; Ruggedness testing and validation of a practical analytical method for >100 veterinary drug residues in bovine muscle by ultrahigh performance liquid chromatography–tandem mass spectrometry. J.Chromatogr A. 2012, 1258, 43-54.