Solid Phase Extraction

SPE Cartridges (Tubes) - Phase Selection Guide

 Standard SPE Phases

 
Your Sample
Matrix is:
Aqueous
(biological fluids, water,
aqueous extracts of tissues, etc.)
Organic
(organic extracts of tissues,
hexane, dichloromethane, etc.)
Recommended
Retention
Mechanism:
Reversed-Phase Ion-Exchange Normal Phase
Analyte
Characteristics:
Moderately polar to
non-polar compounds
Weak
cations / anions
Strong
cations / anions
Polar to moderately
polar compounds
Application Pharma. Environ./Food Pharma. Environ./Food Pharma. Environ./Food Pharma. Environ./Food
Recommended
SPE Phase:
DSC-18
DSC-18Lt
DSC-8
DSC-Ph
DSC-CN
DPA-6S
Supel-Select HLB
ENVI™-18
ENVI-8
ENVI-Chrom P
LC-18
LC-8
LC-Ph
LC-CN
Supel-Select HLB
DSC-SAX
DSC-SCX
Supel-Select SAX
Supel-Select SCX
LC-SAX
LC-SCX
Supel-Select SAX
Supel-Select SCX
DSC-WCX
DSC-NH2
LC-WCX
LC-NH2
PSA
DSC-Si
DSC-CN
DSC-Diol
DSC-NH2
ENVI-Florisil®
LC-Alumina
LC-Florisil
LC-Si
LC-NH2
LC-Diol
LC-CN
PSA

 

The SPE Tube Configuraton Guide will help you choose the appropriate bed weight and cartridge dimensions.


    Supelco now offers SPE sample packs to make
    the phase selection process easier.

 

 Specialty SPE Phases

 
Phase Description Application
Pharmaceutical
HybridSPE-PL Phospholipid removal from plasma and serum samples to reduce ion suppression in LC-MS
Supel-Select HLB SPE Hydrophilic modified styrene polymer ideal for extracting a very broad range of compounds from aqueous samples… at a price you desire!
Discovery DSC-MCAX Mixed-mode cation exchange for superior selectivity/sample cleanup when extracting basic compounds (most pharmaceuticals) from biological fluids (e.g., plasma, urine, etc.)
Polymer SAX Rezorian™ Cartridge Strong cation and anion exchanger on a styrene base particle. Offers much higher ion-exchange capacity Polymer SCX Reversible Tube than silica based ion-exchangers
Supelclean LC-4 (wide pore) Used for desalting proteins/peptides and other macromolecules
SupelMIP™ SPE Tubes Molecular imprinted polymers for the highly selective extraction of trace analytes in difficult sample matrices
Food & Beverage
SupelMIP™ SPE Tubes Molecular imprinted polymers for the highly selective extraction of trace analytes in difficult sample matrices
Discovery Ag-Ion Silver Ion SPE for the fractionation of cis-trans isomers and other FAMEs
Supelclean ENVI-Carb Extreme affinity for polar compounds in aqueous samples and water miscible organic extracts.
Commonly used in pesticide analysis of food samples
Discovery DPA-6S Polyamide resin that adsorbs polar compounds containing multi –OH and –COOH groups. Useful for extracting polyphenolics and other natural compounds (e.g., flavenoids, chlorophyll, humic acid, etc.) from plant extracts
Multi-layer Supelclean
SPE Products (ENVI-Carb™, SAX, PSA, NH2)
, Supel™ Sphere C/NH2
Developed to provide superior cleanup when conducting multi-residue pesticide analysis in food/agricultural matrices
QuEChERS Dispersive SPE Popular QuEChERS (Quick, Easy, Cheap, Effective, Rugged, and Safe) sample prep technique for multi-pesticide residue analysis in food and agricultural products
Supel-Select HLB SPE Hydrophilic modified styrene polymer ideal for extracting a very broad range of compounds from aqueous samples… at a price you desire!
Environmental
Supelclean ENVI-Carb Plus SPE Spherical carbon particles engineered for the extraction of highly polar compounds from aqueous samples such as drinking and ground water.
Supelclean Coconut Charcoal SPE Extraction of nitrosamines in drinking water (US EPA Method 521)
Supelclean ENVI-Carb Extreme affinity for polar compounds in aqueous samples and water miscible organic extracts.
Commonly used in pesticide analysis of food samples
Supelclean™ Sulfoxide SPE Trace level extraction of PCBs and other aromatic compounds from difficult oil samples under normal-phase conditions
Supelclean™ ENVI-18
and –8 DSK SPE Disks
Provides fast flow rates for processing large volumes of water samples
(≥ 0.5 L). Used in EPA 500 series methods – Drinking Water
Dual Layer Florisil/Na2SO4 For total petroleum hydrocarbon index according to European Method EN9377-2
Supel-Select HLB SPE Hydrophilic modified styrene polymer ideal for extracting a very broad range of compounds from aqueous samples… at a price you desire!
SupelMIP™ SPE Tubes Molecular imprinted polymers for the highly selective extraction of trace analytes in difficult sample matrices

We also offer a variety of Unique Products & Hardware.