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Fluorous Chemistry

Catalysts and Ligands


Biphasic catalysis was the first application of fluorous chemistry in 1994. Since that time, fluorous biphasic catalytic methods have advanced rapidly, and a large number of fluorous catalysts and ligands (especially phosphines) are known. The defining feature of FBC is the use of a fluorous reaction solvent, and the technique is best viewed as a liquid phase catalyst immobilization method.


Fluorous Phosphines
Fluorous phosphines have been extensively used as metal ligands in fluorous biphasic catalysis. By varying the number and length of the fluorous chains, reaction and separation characteristics can be tuned. Fluorous phosphines and their oxides can be easily removed using either fluorous solid phase extraction or fluorous liquid-liquid extraction.


Triphenylphosphine


 

FTI Product: F017039 (07026)

Triphenylphosphine Structure Image

Fluorous triphenylphosphine, F017039, is often used in conjunction with the fluorous DIAD for traditional solution phase Mitsunobu chemistry and in biphasic catalysis.
Application Note



Triphenylphosphine, Ethylene Spacer


 

FTI Products: F026040 (19971), F034040 (16367)

Triphenylphosphine, Ethylene Spacer Structure Image



Triphenylphosphine, Branched


 

FTI Product: F026041 (50476)

Triphenylphosphine, Branched Structure Image



Triphenylphosphine, No Spacer


 

FTI Products: F039038 (12118), F051038 (07086)

Triphenylphosphine, No Spacer Structure Image



Triphenylphosphine, Ethylene Spacer


 

FFTI Product: F039042 (49317)

Triphenylphosphine, Ethylene Spacer Structure Image



Triphenylphosphine, Branched


 

FTI Product: F039043 (67301)

Triphenylphosphine, Branched Structure Image


Other Fluorous Phosphines

 

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