Hematology & Histology

Hematoxylin

Hematoxylin is the most widely used natural dye and is extracted from the heartwood of the logwood tree. The tree is native to Central America and extracts were used for dying purposes over 500 years ago. Various formulations of the dye, such as Mayer's, Gill's and Harris' have been used to stain nulcei, mitochondria, mucin, elastic fibers, muscle, collagen, myelin sheaths and phospholipids. Proper staining hematoxylin solutions require oxidation of the dye followed by linking to a metal mordant, typically aluminum.

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Certified Hematoxylin