Biological Buffers

MOPSO

Synonym: 3-morpholinopropanesulfonic acid
 

MOPSO is a zwitterionic aminosulfonate buffer that is very similar in structure to MOPS (3-morpholinopropanesulfonic acid), differing by the presence of a hydroxyl group on C-2 of the propane moiety1. The effect of MOPSO and other Good buffers on the resolution of DNA using discontinuous electrophoresis on rehydratable polyacrylamide gels has been examined2.
Useful pH Range 6.2 - 7.6
Working concentration range 500mM

 

        Comparison of products by grade or quality level
Name CAS Molecular Formula Mol Wt Reagent Grades Life Science Grades PharmaGrade  Solution
MOPSO 68399-77-9 C7H15NO5S 225.26

M8389

 

RES0196M-B7 

 
MOPSO sodium salt 79803-73-9 C7H14NNaO5S 247.24

M8767 

M5914

RES0199M-A7

 

 

Interaction Comments
 

Changes the hydration state of the polymer3
Strong interaction with Fe; weak interaction with Ni4

 

Literature References

  1. Good, N. E., et al, Hydrogen ion buffers for biological research. Biochemistry, 5(2), 467-477 (1966).
  2. Allen, R. C., et al., Resolution of DNA in the presence of mobility modifying polar and nonpolar compounds by discontinuous electrophoresis on rehydratable polyacrylamide gels. Appl. Theor. Electrophor., 3(3-4), 173-181 (1993).
  3. Mohamed Taha et al. "Interactions of Biological Buffers with Macromolecules: The Ubiquitous “Smart” Polymer PNIPAM and the Biological Buffers MES, MOPS, and MOPSO; Macromolecules, 2011, 44 (21), pp 8575–8589. Ferreira CM.
  4. Pinto IS, Soares, EV, Soares HM. 2015 Royal Society of Chemistry 30989- 31003.
  5. Ferreira CM, Pinto IS, Soares, EV, Soares HM. 2015 Royal Society of Chemistry 30989- 31003.