Attention:

Certain features of Sigma-Aldrich.com will be down for maintenance the evening of Friday August 18th starting at 8:00 pm CDT until Saturday August 19th at 12:01 pm CDT.   Please note that you still have telephone and email access to our local offices. We apologize for any inconvenience.

Custom siRNA Oligos

siRNA Design Service

Our in-house design service provides you with customized siRNA designs that efficiently silence your gene of interest. We continuously improve our design rules in order to provide you with highly efficient siRNA sequences. All siRNA designs are routinely analyzed by an optimized BLAST search to reduce the risk of off-target effects.

For accessing our siRNA design service, please contact us under: acctreps-hou@sial.com

For our design process, we will need the following information about your target gene:

  • Reference gene accession number or Gene ID
  • Gene name or Gene symbol

Your siRNA designs will be sent to you by email within 3 working days of submitting your design request. Our design service is free of charge and not linked to any synthesis requirements.

Recommendations
We recommend that you order at least 3 different siRNA designs per gene, to better control for the appearance of off-target effects.

Related Information

1. Tuschl,T., Elbashir,S., Harborth,J., and Weber,K. "The siRNA User Guide,"
http://www.rockefeller.edu/labheads/tuschl/sirna.html(revised May 6, 2004)