Recombinant Limpet β-Glucuronidase

Accelerating Hydrolysis Efficiency

  • Greater than 90% hydrolysis of codeine-6-glucuronide in 15 minutes
  • Eliminate 6-MAM → morphine conversion
  • 2 year shelf life
  • Broad efficacy across substrates

Codeine-Glucuronide Conversion Time-Course

Codeine-Glucuronide Conversion Time-Course

50 U/μL enzyme in spiked urine at 1000 ng/mL glucuronide (nominal)
Enzyme used as supplied (pH 5.0)
70 °C hydrolysis temperature
 

Percent Conversion — 15 Minutes, 70 °C

Percent Conversion — 15 Minutes, 70 °C

For more information on SRE0093 rLimpet, visit Sigma-Aldrich.com/betagluc.
 

 Product Specifications

Physical Description: Clear aqueous solution
Specific Activity: 100,000 – 200,000 units/mL
Shelf Life: 2 years
Storage Temperature: 2 – 8 °C
 

Product No. Product Description Add to Cart
SRE0093 β-Glucuronidase from limpets (Patella vulgata) aqueous solution, 100,000 – 200,000 U/mL

 

 Optimize Your Hydrolysis

Ensure accuracy and efficiency of analytical results using glucuronide reference standards for hydrolysis controls.

Our reference material portfolio offers a wide selection of Certified Reference Materials (CRMs) for glucuronides of numerous drug classes including:

  • Opiates
  • Anesthetics
  • Steroids
  • Hormones
  • Benzodiazepines
  • Ethanol
  • Synthetic analgesics
  • NSAIDS
  • Cannabinoids

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Analytical Workflow