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Plant Profiler

Chickweed (Stellaria media)


Chickweed (Stellaria media) Image
Synonyms / Common Names / Related Terms
Borneol, Caryophyllaceae (family), common chickweed, linalool, menthol, Stellaria holostea, Stellaria longipes, Stellaria media, Stellaria media Cyrill., Stellaria media Villars, terpenes.





Mechanism of Action

Pharmacology:

  • Constituents: The following constituents have been isolated from chickweed essential oil: borneol, menthol, linalool, 1,8-cineole, and other terpenes such as epoxy-dehydro-caryophyllene, monoterpene alcohol-ester and caryophyllene.4 The carotenoid content of Stellaria media Villars. was found to be 4.2mg/100g.1
  • Antibacterial effects: A methanol extract of Stellaria holostea was found to have antibacterial activity against one bacterial species in vitro.3
  • Anti-hepatoma effects: Stellaria media Cyrill. (and 14 other crude drugs used as folk medicine in Canada) were evaluated for their anti-hepatoma activity on five human liver-cancer cell lines.2 The outcome measure was the cytotoxicity of the samples in vitro. Results showed that the crude drugs had different effects on cell lines containing hepatitis B virus genome, vs. non hepatitis B virus genome-containing cell lines.
  • Hepatic effects: Stellaria media Cyrill. (and 14 other crude drugs used as folk medicine in Canada) were evaluated for their anti-hepatoma activity on five human liver-cancer cell lines.2 The outcome measure was the cytotoxicity of the samples in vitro. Results showed that the crude drugs had different effects on cell lines containing hepatitis B virus genome, vs. non hepatitis B virus genome-containing cell lines.
  • Hepatitis B virus effects: Stellaria media Cyrill. (and 14 other crude drugs used as folk medicine in Canada) were evaluated for their anti-hepatoma activity on five human liver-cancer cell lines.2 The outcome measure was the cytotoxicity of the samples in vitro. Results showed that the crude drugs had different effects on cell lines containing hepatitis B virus genome, vs. non hepatitis B virus genome-containing cell lines.
  • Vasodilator effects: Based on animal study, cyclic peptides (dichotomins J and K) isolated from the roots of Stellaria dichotoma showed a moderate vasorelaxant effect on rat aorta.5

Pharmacodynamics/Kinetics:

  • Insufficient available evidence.

Refeences

  1. Guil, J. L., Rodriguez-Garcia, I., and Torija, E. Nutritional and toxic factors in selected wild edible plants. Plant Foods Hum Nutr 1997;51(2):99-107. 9527345
  2. Lin, L. T., Liu, L. T., Chiang, L. C., and Lin, C. C. In vitro anti-hepatoma activity of fifteen natural medicines from Canada. Phytother Res 2002;16(5):440-444. 12203264
  3. Kumarasamy, Y., Cox, P. J., Jaspars, M., Nahar, L., and Sarker, S. D. Screening seeds of Scottish plants for antibacterial activity. J Ethnopharmacol 2002;83(1-2):73-77. 12413709
  4. Jovanovic, M., Mimica-Dukic, N., Poljacki, M., and Boza, P. Erythema multiforme due to contact with weeds: a recurrence after patch testing. Contact Dermatitis 2003;48(1):17-25. 12641574
  5. Morita, H., Iizuka, T., Choo, C. Y., Chan, K. L., Itokawa, H., and Takeya, K. Dichotomins J and K, vasodilator cyclic peptides from Stellaria dichotoma. J Nat Prod 2005;68(11):1686-1688. 16309326




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