Synthetic Biology is the combination of engineering principles and molecular biology techniques to produce novel biological solutions. Sigma® Life Science offers the building blocks for synthetic biology projects, including oligonucleotides and CRISPR genome editing reagents, as well as custom engineered cell lines and metabolic assays for researchers requiring a more advanced solution. The exciting new field of Synthetic Biology promises to expand our capabilities and understanding of food, chemical, and biofuel production, drug and vaccine development, and the progression of complex disease.
To learn more about Synthetic Biology, visit our Synthetic Biology Resources page.
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Sigma-Aldrich Provides Products for Multiple Synthetic Biology Research Applications
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| Circuit Design & Metabolic Pathway Engineering |
| Products for use in production of biofuels, proteins, enzymes, and bio-based chemicals. • Molecular Cloning Tools • SnapFast(TM) Expression Vectors with free editing on Genome Compiler's platform • Microbial Transformation & Culture • Nucleic Acid Purification • Cell Culture and Transfection • PCR • Custom DNA Oligos • Gene Editing with CRISPR • Gene Editing with Zinc Finger Nuclease (ZFN) • siRNA • Metabolic Quanitification Kits |
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| Agriculture & Industrial Manufacturing |
| Research tools used in plant engineering. • Plant Tissue Culture • Plant miRNA, mRNA & total RNA, and genomic DNA • Plant Proteomics • Plant Immunochemistry • Plant Biotechnology • Algae Culture Medium • Custom Plant Culture Medium • Microbial Culture Medium |
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| Life Science Research |
| Research tools by Sigma-Aldrich: enabling science to improve the quality of life. • SnapFast™ Expression Vectors • Molecular Cloning Tools • Microbial Transformation & Culture • Nucleic Acid Purification • Cell Culture and Transfection • PCR • Custom DNA Oligos • Mission TRC3 Human LentiORF Collection • Gene Editing with CRISPR • Gene Editing with Zinc Finger Nuclease (ZFN) • Custom Engineered Cell Lines (Cell Design Studio) |
Across All Applications, Sigma-Aldrich Provides Many Products and Services for Use in Synthetic Biology Engineering Projects
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| Gene Editing Technologies |
| High specificity genome editing (knockout/knock-in) in cell culture and transgenic animal generation. • CRISPR • Zinc Finger Nuclease (ZFN) • TargeTron® Gene KnockOut System (for bacteria) |
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| Custom DNA Oligonucleotides |
| Sigma's custom oligonucleotide portfolio will meet your needs with a wide selection of: • Scales • Purifications • Modifications • Formatting options |
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| Molecular Biology Tools |
| Products for use in engineering projects using microbes: • Metabolic pathway engineering • Circuit design • Yeast chassis |
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| Custom Engineered Cell Lines (Cell Design Studio) |
| Genetically modified cell lines, cell culture media and reagents for use in: • Basic research • Cell based assays • Drug discovery • Target validation |
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| Agriculture & Industrial Applications |
| • Enzymes for Biofuel Research • Biofuels Manufacturing and Testing • Bio-based chemicals & reagents • Bio-sensing & Environmental remediation • Microbial biochemical synthesis • Natural Flavors & Fragrances |
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| MISSION TRC3 Human LentiORF Collection |
| Skip PCR, cloning, and DNA verification steps: • Expression ready lentiviral system • Quickly move from gene expression to protein analysis • Fully sequenced human ORF expression library (whole genome) |