GC Analysis of Amphetamine Enantiomers (N-Trifluoroacetyl Derivatives) on Astec® CHIRALDEX® G-DP

GC Analysis of Amphetamine Enantiomers (N-Trifluoroacetyl Derivatives) on Astec® CHIRALDEX® G-DP

Conditions

column Astec CHIRALDEX G-DP, 30 m x 0.25 mm I.D., 0.12 µm (78033AST)
oven 140 °C
carrier gas helium, 2.7 mL/min., constant flow
sample 4 mg/mL each compound in methylene chloridepeak 1: d-amphetamine (N-TFA derivative)peak 2: l-amphetamine (N-TFA derivative)
injection 1 µL, 80:1 split
liner 4 mm I.D., FocusLiner
inj. temp. 250 °C
detector FID, 250 °C

Description

Analysis Note Elution order reversal (l,d) by using CHIRALDEX G-PN, 130°C (see G005053).
Categories Analytical Chromatography, Chiral Applications, GC Applications, Clinical, Forensic & Toxicology, Enantiomers, Pharmaceuticals, Drugs of Abuse, Amines
Featured Industry Clinical
Forensics and Toxicology
Pharmaceutical (small molecule)
Legal Information Astec is a registered trademark of Sigma-Aldrich Co. LLC, CHIRALDEX is a registered trademark of Sigma-Aldrich Co. LLC
Other Notes Complementary products:
Syringes
Vials
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Septa and Specialized Hand Tools
Column Ferrules, Nuts, and Specialized Hand Tools
suitability application for GC

Materials

     
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