GC Analysis of Class 3 Residual Solvents on Equity®-1 after SPME using 100 μm PDMS Fiber

GC Analysis of Class 3 Residual Solvents on Equity®-1 after SPME using 100 μm PDMS Fiber

Conditions

sample/matrix 2 mL water + sodium chloride at 25% (pH 2) containing each analyte at 5 ppm, in a 4 mL vial
desorption process 250 C for 3 min
extraction heated headspace, 60 C for 5 min
SPME fiber 100 µm PDMS, 24 ga manual (57300-U)
column Equity-1, 10 m x 0.20 mm I.D., 1.2 µm (28043-U)
oven 40 C (0.75 min), 20 C/min to 200 C (10 min)
carrier gas helium, 35 cm/sec @ 4
injection 5:1 split
liner 0.75 mm I.D. SPME type
inj. temp. 250 C
detector FID

Description

Categories Analytical Chromatography, SPME Applications, GC Applications, Solvents
Featured Industry Pharmaceutical (small molecule)
Legal Information Equity is a registered trademark of Sigma-Aldrich Co. LLC
suitability application for SPME, application for GC

Analyte

  • 1-Butanol
  • 1-Propanol
  • 2-Butanone
  • 2-Propanol
  • 4-Methyl-2-pentanone
  • Acetone
  • Anisole
  • Butyl acetate
  • Cumene
  • Dimethyl sulfoxide
  • Ethanol
  • Ethyl acetate
  • Ethyl ether
  • Ethyl formate
  • Heptane
  • Isoamyl alcohol
  • Isobutanol
  • Isobutyl acetate
  • Isopropyl acetate
  • Methyl acetate
  • Methyl-t-butyl ether
  • n-Amyl alcohol
  • Pentane
  • Propyl acetate
  • sec-Butanol
  • Tetrahydrofuran (THF)

Materials

     
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