GC Analysis of Phthalate Esters in Perfume on SLB®-5ms (20 m x 0.18 mm I.D., 0.18 μm), Fast GC Analysis

GC Analysis of Phthalate Esters in Perfume on SLB®-5ms (20 m x 0.18 mm I.D., 0.18 μm), Fast GC Analysis

Conditions

column SLB-5ms, 20 m x 0.18 mm I.D., 0.18 µm (28564-U)
oven 60 C (1 min), 10 C/min to 330 C (10 min)
carrier gas helium, 0.6 ml/min, constant
sample cologne sample spiked at 100 µg/mL with various phthalate esters
liner 4 mm ID focus liner with taper
inj. temp. 250 C

Description

Analysis Note Phthalate esters are commonly used as plasticizers and additives for various materials. In the case of some fragrances, diethyl phthalate is used as a solvent and deluent. Rising concern with the potential health effects of exposure to phthalate esters has lead to some controversy over their use in fragrances and other personal care products. This application illustrates the use of GC-MS to analyze a cologne sample that has been spiked at 100 ug/ml with a list of phthalate esters. The unspiked sample was found to contain diethyl phthalate.
The SLB-5ms column was chosen for the analysis due to its low bleed/MS compatibility. The nonpolar character of the phase resulted in elution of the lower boiling constituents in the cologne sample prior to most of the phthalate esters. A 20 m x 0.18 mm ID x 0.18 μm column was used to reduce overall analysis time.
Categories Analytical Chromatography, GC Applications, Phthalate Esters
Featured Industry Cosmetics, Personal Care, and Cleaning Products
General description Diethyl phthalate was detected in the unspiked sample.
Legal Information SLB is a registered trademark of Sigma-Aldrich Co. LLC
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suitability application for GC

Materials

     
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