GC Analysis of Residual Solvents in Hemp Extract on Supel-Q™ PLOT after Headspace SPME using 75 μm Carboxen®/PDMS Fiber

GC Analysis of Residual Solvents in Hemp Extract on Supel-Q™ PLOT after Headspace SPME using 75 μm Carboxen®/PDMS Fiber

Conditions

sample preparation fiber post bake: 2 min, 320 C
sample preparation Solid Phase Microextraction
sample/matrix 5 g sample in 10 mL vial
desorption process 3 min, 320 C; split 10:1
extraction 5 min, headspace, 40 C
SPME fiber SPME fiber assembly Carboxen/Polydimethylsiloxane (CAR/PDMS) (57319)
column Supel-Q(TM) PLOT, 30 m x 0.32 mm I.D. (24242)
oven 50 C (5 min), 10 C/min to 230 C (5 min)
carrier gas helium, 2 ml/min constant flow
injection split, 10:1
liner SPME, 0.75 mm I.D.
inj. temp. 320 C
detector MSD
MSD interface 260 C
scan range m/z 29-200

Description

Analysis Note Marijuana oil is produced by extraction of the flower buds of the cannabis sativa plant. This process often involves the use of solvents such as hexane or some alcohols. Even though measures are taken to remove these solvents after extraction, some residual material may remain behind in the final product. In this work, headspace SPME was used to analyze residual solvents from an extract of hemp. For the analysis, hemp extract was used for testing in lieu of marijuana extract, which could not be obtained in the location where the work was done. Hemp and marijuana are both varieties of cannabis sativa, however hemp is a variety that is very low in THC content.
Categories Analytical Chromatography, GC Applications, Solvents
Featured Industry Agriculture
Chemicals and Industrial Polymers
Flavors and Fragrances
Pharmaceutical (small molecule)
Legal Information Supel-Q is a trademark of Sigma-Aldrich Co. LLC, Carboxen is a registered trademark of Sigma-Aldrich Co. LLC
suitability application for SPME, application for GC

Materials

     
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