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HPLC Analysis of 3,4-Methylenedioxypyrovalerone (MDPV) Enantiomers on Astec® CHIROBIOTIC® V2

HPLC Analysis of 3,4-Methylenedioxypyrovalerone (MDPV) Enantiomers on Astec® CHIROBIOTIC® V2

Conditions

column Astec CHIROBIOTIC V2 15 cm x 4.6 mm I.D., 5 µm particles (15023AST)
column temp. 20 C
mobile phase [A] methanol; [B] water; [C] acetic acid; [D] ammonium hydroxide; (95:5:0.1:0.02, A:B:C:D)
flow rate 1 ml/min
pressure 1100 psi (70 bar)
sample 100 µg/mL in methanol
injection 5 µl
detector UV, 235 nm

Description

Analysis Note 3,4-Methylenedioxypyrovalerone, also known as MDPV, Mtv, or Super Coke, is a new designer drug and stiµlant with cases of abuse reported in Europe and the US. In mid- to late-2010, MDPV started appearing in the US as a legal drug alternative marketed as “bath salts” under names including Ivory Wave, Tranquility, and Cloud 9. Astec CHIROBIOTIC V2, based on vancomycin CSP, provided resolution of the enatiomers. CRMs from Cerillliant provided reliable identification and quantification.
Categories Analytical Chromatography, Drugs of Abuse
Featured Industry Forensics and Toxicology
Legal Information CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC, Astec is a registered trademark of Sigma-Aldrich Co. LLC
suitability application for HPLC

Materials

     
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