HPLC Analysis of a Metalaxyl Enantiomers on Kromasil® AmyCoat®

HPLC Analysis of a Metalaxyl Enantiomers on Kromasil® AmyCoat®

Conditions

column Kromasil AmyCoat, 25 cm x 4.6 mm I.D., 5 µm particles
column temp. 25 °C
mobile phase [A] ethanol; [B] hexane, (25:75, A:B)
flow rate 1 mL/min
pressure 943 psi (65 bar)
sample 1 mg/mL in ethanol
injection 10 µL
detector UV, 220 nm

Description

Analysis Note Metalaxyl is a 1:1 mixture of ®- and (S)-2-[(2,6-dimethylphenyl)methoxyacetylamino]propionic acid methyl ester. Both enantiomers are fungicides used in agriculture, horticulture, and forestry. They act by inhibiting mycelial growth and spore formation. Metalaxyl-M is the biologically active ®-enantiomer. Technical-grade metalaxyl-M consists of a miniµm of 97% of the ®-enantiomer and 3% of the (S)-enantiomer. Chiral LC on Kromasil AmyCoat was used to separate the two enantiomers.
Categories Analytical Chromatography, Fungicides
Featured Industry Agriculture
Environmental
Legal Information Kromasil is a registered trademark of EKA Chemicals AB, AmyCoat is a registered trademark of EKA Chemicals AB
suitability application for HPLC

Materials

     
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