HPLC Analysis of Oxprenolol Enantiomers on Astec® Cellulose DMP

HPLC Analysis of Oxprenolol Enantiomers on Astec® Cellulose DMP

Conditions

column Astec Cellulose DMP, 25 cm x 4.6 mm I.D., 5 µm particles (51099AST)
column temp. 30 C
mobile phase [A] heptane; [B] isopropanol; [C] diethylamine; (80:20:0.1, A:B:C)
flow rate 1 ml/min
sample oxprenolol, 1 g/L in 50:50 heptane:isopropanol
injection 15 µl
detector UV, 254 nm

Description

Analysis Note Oxprenolol enantiomers are resolved by normal phase chromatography.
Categories Analytical Chromatography, Antihypertensives
Featured Industry Pharmaceutical (small molecule)
Legal Information Astec is a registered trademark of Sigma-Aldrich Co. LLC
Other Notes Oxprenolol is a nonselective beta-blocker and is used to treat angina and hypertension.
suitability application for HPLC

Materials

     
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