HPLC Analysis of Tryptophan Hydroxylase Inhibitors on Ascentis® C18

HPLC Analysis of Tryptophan Hydroxylase Inhibitors on Ascentis® C18

Conditions

column Ascentis C18, 15 cm x 4.6 mm I.D., 5 µm particles (581324-U)
column temp. 35 °C
mobile phase [A] 40 mM formic acid, (pH ~2.5): [B] methanol; (65:35, A:B)
flow rate 0.7 mL/min
sample as indicated in 90:10, 10 mM formic acid:methanol
injection 10 µL
detector full scan MS; overlay of extracted ion chromatograms of individual (M+H)+ species

Description

Categories Analytical Chromatography, Clinical, proteins, Amino Acids
Featured Industry Clinical
Pharmaceutical (small molecule)
Legal Information Ascentis is a registered trademark of Sigma-Aldrich Co. LLC
suitability application for HPLC

Materials

     
Related Links