Analysis of Typical Parent Antipsychotic Drugs Using a Titan™ 120A C18 Column

Analysis of Typical Parent Antipsychotic Drugs Using a Titan™ 120A C18 Column

Conditions

column Titan 120 °C18, 10 cm  x 3.0 mm, I.D., 1.9 µm particles (577160-U)
column temp. 35 °C
mobile phase [A] 0.1% formic acid in water, [B] 0.1 formic acid in methanol
gradient 25% B for 2 minutes followed by a linear gradient to 95% B for 10 minutes, followed by a hold at 95% B for 2 minutes.
flow rate 0.5 mL/min
sample 25 µg/mL each in 10% methanol
injection 2 µL
detector UV, 245 nm

Description

Analysis Note An application was developed on Titan 120 °C18 to separate typical parent antipsychotics.
Categories Analytical Chromatography, Antipsychotics
Featured Industry Pharmaceutical (small molecule)
Legal Information Titan is a trademark of Sigma-Aldrich Co. LLC
suitability application for HPLC

Materials

     
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